{"id":519,"date":"2026-05-05T14:08:10","date_gmt":"2026-05-05T05:08:10","guid":{"rendered":"https:\/\/rmnw.jp\/teams\/?p=519"},"modified":"2026-05-05T14:08:12","modified_gmt":"2026-05-05T05:08:12","slug":"rm13-%e7%ac%ac%e5%8d%81%e4%b8%89%e7%ab%a0-%e8%86%a0%e5%8e%9f%e7%97%85%e3%83%bb%e3%83%aa%e3%82%a6%e3%83%9e%e3%83%81%e7%a7%91","status":"publish","type":"post","link":"https:\/\/rmnw.jp\/teams\/?p=519","title":{"rendered":"RM13.\u7b2c\u5341\u4e09\u7ae0 \u81a0\u539f\u75c5\u30fb\u30ea\u30a6\u30de\u30c1\u79d1"},"content":{"rendered":"\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"RM13.\u7b2c\u5341\u4e09\u7ae0 \u81a0\u539f\u75c5\u30fb\u30ea\u30a6\u30de\u30c1\u79d1\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/BeRHaen--a8?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n\t\t<div class=\"wppdfemb-frame-container-1\" style=\"-webkit-overflow-scrolling:auto;\">\n\t\t\t<iframe class=\"pdfembed-iframe nonfullscreen wppdf-emb-iframe-1\"\n\t\t\t\tsrc=\"https:\/\/rmnw.jp\/teams\/?pdfemb-data=eyJwZGZJRCI6NTIwLCJ1cmwiOiJodHRwczpcL1wvcm1udy5qcFwvdGVhbXNcL3dwLWNvbnRlbnRcL3VwbG9hZHNcLzIwMjZcLzA1XC9STTEzLlx1N2IyY1x1NTM0MVx1NGUwOVx1N2FlMC1cdTgxYTBcdTUzOWZcdTc1YzVcdTMwZmJcdTMwZWFcdTMwYTZcdTMwZGVcdTMwYzFcdTc5ZDEucGRmIiwiaW5kZXgiOjF9\"\n\t\t\t\t\t\t\t\tdata-pdf-id=\"520\"\n\t\t\t\tdata-pdf-index=\"1\"\n\t\t\t\tstyle=\"border:none;width:100%;max-width:100%;height:100vh;\"\n\t\t\t\tscrolling=\"yes\">\n\t\t\t<\/iframe>\n\t\t<\/div>\n\n\t\t\n\n\n<h1 class=\"wp-block-heading\">\u81a0\u539f\u75c5\u30fb\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u306b\u304a\u3051\u308bCAR-T\u7d30\u80de\u7642\u6cd5\u306e\u5c55\u671b\uff1a\u9769\u65b0\u7684\u300c\u514d\u75ab\u30ea\u30bb\u30c3\u30c8\u300d\u306e\u5b9f\u73fe\u306b\u5411\u3051\u3066<\/h1>\n\n\n\n<h2 class=\"wp-block-heading\">\u30a8\u30b0\u30bc\u30af\u30c6\u30a3\u30d6\u30fb\u30b5\u30de\u30ea\u30fc<\/h2>\n\n\n\n<p>\u73fe\u5728\u3001\u81a0\u539f\u75c5\u304a\u3088\u3073\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u306e\u6cbb\u7642\u9818\u57df\u306b\u304a\u3044\u3066\u3001CAR-T\uff08\u30ad\u30e1\u30e9\u6297\u539f\u53d7\u5bb9\u4f53T\u7d30\u80de\uff09\u7642\u6cd5\u306b\u3088\u308b\u300c<strong>Deep depletion and reset\uff08\u6df1\u3044\u67af\u6e07\u3068\u30ea\u30bb\u30c3\u30c8\uff09<\/strong>\u300d\u304c\u3001\u5f93\u6765\u306e\u5bfe\u75c7\u7642\u6cd5\u3092\u6253\u7834\u3059\u308b\u30d1\u30e9\u30c0\u30a4\u30e0\u30b7\u30d5\u30c8\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u308b\u3002<\/p>\n\n\n\n<p>\u672c\u30c9\u30ad\u30e5\u30e1\u30f3\u30c8\u306f\u3001\u63d0\u4f9b\u3055\u308c\u305f\u30bd\u30fc\u30b9\u306b\u57fa\u3065\u304d\u3001\u5168\u8eab\u6027\u30a8\u30ea\u30c6\u30de\u30c8\u30fc\u30c7\u30b9\uff08SLE\uff09\u3001\u5168\u8eab\u6027\u5f37\u76ae\u75c7\uff08SSc\uff09\u3001\u7279\u767a\u6027\u708e\u75c7\u6027\u7b4b\u75be\u60a3\uff08IIM\uff09\u7b49\u306e\u96e3\u6cbb\u6027\u75be\u60a3\u306b\u5bfe\u3059\u308bCAR-T\u7642\u6cd5\u306e\u81e8\u5e8a\u7684\u6709\u7528\u6027\u3001\u5b89\u5168\u6027\u3001\u304a\u3088\u3073\u6280\u8853\u7684\u9032\u5c55\u3092\u7dcf\u62ec\u3059\u308b\u3082\u306e\u3067\u3042\u308b\u3002<\/p>\n\n\n\n<p><strong>\u4e3b\u8981\u306a\u8ad6\u70b9\uff1a<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u81e8\u5e8a\u7684\u5bdb\u89e3\u306e\u9054\u6210\uff1a<\/strong> M\u00fcller\u3089\uff082024\u5e74\uff09\u306e\u7814\u7a76\u3067\u306f\u3001SLE\u3001IIM\u3001SSc\u306e\u60a3\u800515\u540d\u5168\u54e1\u306b\u304a\u3044\u3066\u3001CAR-T\u6295\u4e0e\u5f8c\u306b100%\u306e\u7121\u85ac\u5bdb\u89e3\uff08Drug-free remission\uff09\u304c\u78ba\u8a8d\u3055\u308c\u305f\u3002<\/li>\n\n\n\n<li><strong>\u514d\u75ab\u30ea\u30bb\u30c3\u30c8\uff1a<\/strong> CD19\u3092\u6a19\u7684\u3068\u3057\u305fCAR-T\u7642\u6cd5\u306f\u3001\u7d44\u7e54\u6df1\u90e8\u307e\u3067\u6d78\u900f\u3057\u3066\u81ea\u5df1\u6297\u4f53\u7523\u751f\u7d30\u80de\u3092\u67af\u6e07\u3055\u305b\u3001B\u7d30\u80de\u306e\u65b0\u751f\u3092\u901a\u3058\u3066\u514d\u75ab\u306e\u81ea\u5df1\u5bdb\u5bb9\u3092\u518d\u6559\u80b2\u3059\u308b\u3002<\/li>\n\n\n\n<li><strong>\u5b89\u5168\u6027\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\uff1a<\/strong> \u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u653e\u51fa\u75c7\u5019\u7fa4\uff08CRS\uff09\u306fGrade 1\u304c\u5927\u534a\u3067\u3042\u308a\u3001ICANS\uff08\u795e\u7d4c\u6bd2\u6027\uff09\u306e\u767a\u751f\u3082\u6975\u3081\u3066\u9650\u5b9a\u7684\u3067\u3042\u308b\u3002<\/li>\n\n\n\n<li><strong>\u4eca\u5f8c\u306e\u5c55\u671b\uff1a<\/strong> 2025\u5e74\u304b\u30892026\u5e74\u306b\u304b\u3051\u3066\u4e3b\u8981\u306a\u6cbb\u9a13\u30c7\u30fc\u30bf\u306e\u516c\u958b\u3068BLA\uff08\u751f\u7269\u5b66\u7684\u88fd\u5264\u627f\u8a8d\u7533\u8acb\uff09\u304c\u4e88\u5b9a\u3055\u308c\u3066\u304a\u308a\u30012026\u5e74\u306b\u306f\u4e00\u90e8\u306e\u75be\u60a3\u3067\u5b9f\u7528\u5316\u306e\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. CAR-T\u7642\u6cd5\u306e\u9769\u65b0\u6027\u3068\u30e1\u30ab\u30cb\u30ba\u30e0<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">1.1 \u300c\u514d\u75ab\u30ea\u30bb\u30c3\u30c8\u300d\u306e\u30b3\u30f3\u30bb\u30d7\u30c8<\/h3>\n\n\n\n<p>\u5f93\u6765\u306e\u6cbb\u7642\uff08\u30b9\u30c6\u30ed\u30a4\u30c9\u3084\u514d\u75ab\u6291\u5236\u5264\uff09\u304c\u514d\u75ab\u53cd\u5fdc\u306e\u6291\u5236\u306b\u7559\u307e\u308b\u306e\u306b\u5bfe\u3057\u3001CAR-T\u7642\u6cd5\u306f\u81ea\u5df1\u53cd\u5fdc\u6027B\u7d30\u80de\u3092\u5b8c\u5168\u306b\u67af\u6e07\u3055\u305b\u3001\u514d\u75ab\u30b7\u30b9\u30c6\u30e0\u3092\u521d\u671f\u5316\uff08\u30ea\u30bb\u30c3\u30c8\uff09\u3059\u308b\u3053\u3068\u3092\u76ee\u6307\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u6a19\u7684\uff1a<\/strong> \u4e3b\u306bCD19\u3092\u6a19\u7684\u3068\u3057\u3001\u30d7\u30edB\u7d30\u80de\u304b\u3089\u8a18\u61b6B\u7d30\u80de\u3001\u5f62\u8cea\u82bd\u7d30\u80de\u307e\u3067\u3092\u7db2\u7f85\u7684\u306b\u9664\u53bb\u3059\u308b\u3002<\/li>\n\n\n\n<li><strong>\u7d44\u7e54\u6d78\u900f\uff1a<\/strong> \u65e2\u5b58\u306e\u6297CD20\u6297\u4f53\uff08\u30ea\u30c4\u30ad\u30b7\u30de\u30d6\u7b49\uff09\u3068\u6bd4\u8f03\u3057\u3066\u3001\u7d44\u7e54\u3078\u306e\u6d78\u900f\u6027\u304c\u9ad8\u304f\u3001\u6df1\u90e8\u306b\u6f5c\u3080\u81ea\u5df1\u6297\u4f53\u7523\u751f\u7d30\u80de\u306b\u5230\u9054\u53ef\u80fd\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">1.2 \u65e2\u5b58\u7642\u6cd5\u3068\u306e\u6bd4\u8f03\uff08\u6297CD20\u6297\u4f53 vs CD19 CAR-T\uff09<\/h3>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><td>\u7279\u5fb4<\/td><td>\u6297CD20\u6297\u4f53\uff08\u30ea\u30c4\u30ad\u30b7\u30de\u30d6\u7b49\uff09<\/td><td>\u6297CD19 CAR-T\u7642\u6cd5<\/td><\/tr><tr><td><strong>\u7d44\u7e54\u6d78\u900f<\/strong><\/td><td>\u9650\u5b9a\u7684<\/td><td>\u6df1\u3044<\/td><\/tr><tr><td><strong>\u5f62\u8cea\u7d30\u80de\u6a19\u7684<\/strong><\/td><td>CD20\u9670\u6027\u7d30\u80de\u3092\u56de\u907f<\/td><td>\u5f62\u8cea\u82bd\u7d30\u80de\u3092\u6a19\u7684<\/td><\/tr><tr><td><strong>B\u7d30\u80de\u67af\u6e07\u671f\u9593<\/strong><\/td><td>\u4e00\u904e\u6027<\/td><td>\u9577\u671f<\/td><\/tr><tr><td><strong>\u514d\u75ab\u30ea\u30bb\u30c3\u30c8\u52b9\u679c<\/strong><\/td><td>\u306a\u3057\uff08\u7dad\u6301\u7642\u6cd5\u304c\u5fc5\u8981\uff09<\/td><td>\u3042\u308a\uff08\u7121\u85ac\u5bdb\u89e3\u306e\u53ef\u80fd\u6027\uff09<\/td><\/tr><tr><td><strong>\u5b89\u5168\u6027<\/strong><\/td><td>\u78ba\u7acb\u6e08\u307f<\/td><td>\u4e3b\u306bCRS Grade 1<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. \u75be\u60a3\u5225\u81e8\u5e8a\u30a8\u30d3\u30c7\u30f3\u30b9<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">2.1 \u5168\u8eab\u6027\u30a8\u30ea\u30c6\u30de\u30c8\u30fc\u30c7\u30b9\uff08SLE\uff09\u304a\u3088\u3073\u30eb\u30fc\u30d7\u30b9\u814e\u708e\uff08LN\uff09<\/h3>\n\n\n\n<p>SLE\u306f\u65e5\u672c\u306b\u7d0474,277\u4eba\u306e\u60a3\u8005\u304c\u304a\u308a\u3001\u305d\u306e40\u301c50%\u304c\u30eb\u30fc\u30d7\u30b9\u814e\u708e\u3092\u5408\u4f75\u3059\u308b\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u81e8\u5e8a\u6210\u7e3e\uff1a<\/strong> M\u00fcller\u3089\uff082024\u5e74\uff09\u306eSLE\u60a3\u80058\u540d\u306b\u304a\u3044\u3066\u3001SLEDAI-2K\u30b9\u30b3\u30a2\u304c\u5927\u5e45\u306b\u6539\u5584\u3057\u3001\u5168\u4f8b\u3067\u85ac\u7269\u96e2\u8131\u3092\u9054\u6210\u3002<\/li>\n\n\n\n<li><strong>\u4e3b\u8981\u30d1\u30a4\u30d7\u30e9\u30a4\u30f3\uff1a<\/strong>\n<ul class=\"wp-block-list\">\n<li><strong>KYV-101\uff1a<\/strong> NIH\uff08\u7c73\u56fd\u56fd\u7acb\u885b\u751f\u7814\u7a76\u6240\uff09\u958b\u767a\u306e\u6280\u8853\u3092\u4f7f\u7528\u3002ACR 2024\u306b\u3066\u3001B\u7d30\u80de\u306e\u5b8c\u5168\u67af\u6e07\u3068eGFR\u306e\u5b89\u5b9a\u5316\u3001SLE\u81e8\u5e8a\u6539\u5584\u304c\u5831\u544a\u3055\u308c\u305f\u3002<\/li>\n\n\n\n<li><strong>FT819\uff1a<\/strong> iPSC\uff08\u4eba\u5de5\u591a\u80fd\u6027\u5e79\u7d30\u80de\uff09\u7531\u6765CAR-T\u3002TRAC\u9818\u57df\u3078\u306e\u633f\u5165\u306b\u3088\u308aGvHD\uff08\u79fb\u690d\u7247\u5bfe\u5bbf\u4e3b\u75c5\uff09\u30ea\u30b9\u30af\u3092\u4f4e\u6e1b\u3002FDA\u3088\u308aRMAT\u6307\u5b9a\u3092\u53d7\u3051\u3066\u3044\u308b\u3002<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">2.2 \u5168\u8eab\u6027\u5f37\u76ae\u75c7\uff08SSc\uff09<\/h3>\n\n\n\n<p>SSc\u306f\u4e88\u5f8c\u4e0d\u826f\u306aSSc-ILD\uff08\u9593\u8cea\u6027\u80ba\u75be\u60a3\uff09\u3084PAH\uff08\u80ba\u9ad8\u8840\u5727\u75c7\uff09\u3092\u5408\u4f75\u3059\u308b\u96e3\u6cbb\u6027\u75be\u60a3\u3067\u3042\u308b\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>CAR-T vs HSCT\uff08\u9020\u8840\u5e79\u7d30\u80de\u79fb\u690d\uff09\uff1a<\/strong> \u5f93\u6765\u3001\u91cd\u75c7\u4f8b\u306b\u306fHSCT\u304c\u691c\u8a0e\u3055\u308c\u305f\u304c\u3001HSCT\u306f\u79fb\u690d\u95a2\u9023\u6b7b\u4ea1\u30ea\u30b9\u30af\uff083\u301c10%\uff09\u304c\u8ab2\u984c\u3002CAR-T\u306f\u3088\u308a\u5b89\u5168\u306a\u4ee3\u66ff\u7642\u6cd5\u3068\u3057\u3066\u671f\u5f85\u3055\u308c\u308b\u3002<\/li>\n\n\n\n<li><strong>\u6700\u65b0\u30c7\u30fc\u30bf\uff1a<\/strong> M\u00fcller 2024\u3067\u306f4\u540d\u306eSSc\u60a3\u8005\u5168\u54e1\u304c\u81e8\u5e8a\u7684\u6539\u5584\u3092\u793a\u3057\u3001\u4fee\u6b63Rodnan\u30b9\u30ad\u30f3\u30fb\u30b9\u30b3\u30a2\uff08mRSS\uff09\u306e\u6709\u610f\u306a\u4f4e\u4e0b\u304c\u78ba\u8a8d\u3055\u308c\u305f\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">2.3 \u7279\u767a\u6027\u708e\u75c7\u6027\u7b4b\u75be\u60a3\uff08IIM\uff1a\u591a\u767a\u6027\u7b4b\u708e\u30fb\u76ae\u819a\u7b4b\u708e\uff09<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>RESET-Myositis\u8a66\u9a13\uff1a<\/strong> \u6297MDA5\u6297\u4f53\u967d\u6027\u4f8b\u306a\u3069\u3001\u6025\u901f\u9032\u884c\u6027ILD\u3092\u4f34\u3046\u91cd\u75c7\u4f8b\u304c\u5bfe\u8c61\u3002<\/li>\n\n\n\n<li><strong>\u6210\u679c\uff1a<\/strong> M\u00fcller 2024\u306e3\u540d\u304a\u3088\u3073CASTLE\u8a66\u9a13\u306e5\u540d\u306b\u304a\u3044\u3066\u3001ACR\/EULAR\u57fa\u6e96\u3067\u300cMajor Response\u300d\u3092\u9054\u6210\u3002\u6297\u4f53\u4fa1\u306e\u6d88\u5931\u3068\u7b4b\u529b\u306e\u56de\u5fa9\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">2.4 \u91cd\u75c7\u7b4b\u7121\u529b\u75c7\uff08MG\uff09\u304a\u3088\u3073\u30b9\u30c6\u30a3\u30c3\u30d5\u30d1\u30fc\u30bd\u30f3\u75c7\u5019\u7fa4\uff08SPS\uff09<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>MG\uff1a<\/strong> KYSA-6\u8a66\u9a13\u306b\u3066\u3001KYV-101\u6295\u4e0e\u5f8c\u306bMG-ADL\u304a\u3088\u3073QMG\u30b9\u30b3\u30a2\u304c\u5287\u7684\u306b\u6539\u5584\uff08100%\u306e\u6539\u5584\u7387\uff09\u30022027\u5e74\u306e\u627f\u8a8d\u7533\u8acb\u3092\u76ee\u6307\u3057\u3066\u3044\u308b\u3002<\/li>\n\n\n\n<li><strong>SPS\uff1a<\/strong> KYSA-8\u8a66\u9a13\u306b\u3066\u3001\u6b69\u884c\u6a5f\u80fd\uff08T25FW\uff09\u304c46%\u6539\u5584\u3002\u591a\u304f\u304c\u6b69\u884c\u5668\u4e0d\u8981\u306a\u30ec\u30d9\u30eb\u307e\u3067\u56de\u5fa9\u3057\u3001p=0.0003\u3068\u3044\u3046\u6975\u3081\u3066\u9ad8\u3044\u6709\u610f\u5dee\u3092\u793a\u3057\u305f\u3002<\/li>\n<\/ul>\n\n\n\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. \u6b21\u4e16\u4ee3\u6280\u8853\u306e\u9032\u5c55<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">3.1 Ex vivo \u304b\u3089 In vivo \u3078\u306e\u79fb\u884c<\/h3>\n\n\n\n<p>\u5f93\u6765\u306eCAR-T\u306f\u60a3\u8005\u306e\u7d30\u80de\u3092\u4f53\u5916\u3067\u52a0\u5de5\uff08Ex vivo\uff09\u3059\u308b\u5fc5\u8981\u304c\u3042\u3063\u305f\u304c\u3001\u4f53\u5185\uff08In vivo\uff09\u3067\u76f4\u63a5CAR-T\u7d30\u80de\u3092\u4f5c\u6210\u3059\u308b\u6280\u8853\u304c\u958b\u767a\u3055\u308c\u3066\u3044\u308b\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>HN2301\uff1a<\/strong> LNP\uff08\u8102\u8cea\u30ca\u30ce\u7c92\u5b50\uff09\u3068mRNA\u3092\u7528\u3044\u3001\u4f53\u5185\u306eCD8\u967d\u6027T\u7d30\u80de\u306bCD19 CAR\u3092\u767a\u73fe\u3055\u305b\u308b\u3002\u30a2\u30d5\u30a7\u30ec\u30fc\u30b7\u30b9\u3084\u524d\u51e6\u7f6e\u304c\u4e0d\u8981\u306b\u306a\u308b\u53ef\u80fd\u6027\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">3.2 iPSC\u7531\u6765CAR-T<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>FT819\uff1a<\/strong> 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3\u4ee5\u4e0a\uff09\u306f\u6975\u3081\u3066\u7a00\u3002<\/li>\n\n\n\n<li><strong>ICANS\uff08\u514d\u75ab\u7d30\u80de\u95a2\u9023\u795e\u7d4c\u6bd2\u6027\u75c7\u5019\u7fa4\uff09\uff1a<\/strong> \u767a\u751f\u7387\u306f\u6975\u3081\u3066\u4f4e\u304f\u3001\u91cd\u75c7\u5ea6\u306f\u4f4e\u3044\u3002<\/li>\n\n\n\n<li><strong>\u8840\u7403\u6e1b\u5c11\uff1a<\/strong> \u597d\u4e2d\u7403\u6e1b\u5c11\uff08Grade 3\/4\uff09\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u304c\u3001\u591a\u304f\u306f\u56de\u5fa9\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">4.2 \u898f\u5236\u5f53\u5c40\u306e\u8a55\u4fa1<\/h3>\n\n\n\n<p>\u591a\u304f\u306e\u88fd\u54c1\u304cFDA\u306e**RMAT\uff08\u518d\u751f\u533b\u7642\u5148\u9032\u6cbb\u7642\uff09**\u6307\u5b9a\u3084EMA\u306ePRIME\u6307\u5b9a\u3092\u53d7\u3051\u3066\u304a\u308a\u3001\u512a\u5148\u5be9\u67fb\u306e\u5bfe\u8c61\u3068\u306a\u3063\u3066\u3044\u308b\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u9577\u671f\u30d5\u30a9\u30ed\u30fc\u30a2\u30c3\u30d7\uff1a<\/strong> FDA\u306f\u4e8c\u6b21\u6027\u60aa\u6027\u816b\u760d\u306e\u30ea\u30b9\u30af\u8a55\u4fa1\u306e\u305f\u3081\u3001\u6295\u4e0e\u5f8c15\u5e74\u9593\u306e\u9577\u671f\u8ffd\u8de1\uff08LTFU\uff09\u3092\u7fa9\u52d9\u4ed8\u3051\u3066\u3044\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. \u5e02\u5834\u30fb\u5c06\u6765\u4e88\u6e2c<\/h2>\n\n\n\n<p>2026\u5e74\u306f\u3001\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u9818\u57df\u306b\u304a\u3051\u308bCAR-T\u7642\u6cd5\u306e\u300c\u793e\u4f1a\u5b9f\u88c5\u300d\u5143\u5e74\u3068\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>2026\u5e74\u306e\u4e3b\u8981\u30a4\u30d9\u30f3\u30c8\uff1a<\/strong>\n<ul class=\"wp-block-list\">\n<li>KYV-101\uff08SPS\/MG\uff09\u306eBLA\u7533\u8acb\u3002<\/li>\n\n\n\n<li>FT819\uff08SLE\uff09\u306e\u4e3b\u8981\u30c7\u30fc\u30bf\u516c\u958b\u3002<\/li>\n\n\n\n<li>\u6b27\u5dde\u3067\u306e\u4e00\u90e8\u627f\u8a8d\u306e\u53ef\u80fd\u6027\u3002<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u8ab2\u984c\uff1a<\/strong>\n<ul class=\"wp-block-list\">\n<li>\u9ad8\u984d\u306a\u4fa1\u683c\u8a2d\u5b9a\uff08\u764c\u9818\u57df\u3067\u306f4,500\u4e07\u301c6,500\u4e07\u5186\uff09\u3002<\/li>\n\n\n\n<li>\u88fd\u9020\u671f\u9593\uff08Vein-to-Vein\u30bf\u30a4\u30e0\uff09\u306e\u77ed\u7e2e\u3002<\/li>\n\n\n\n<li>\u5916\u6765\u6295\u4e0e\u306e\u5b9f\u73fe\u306b\u5411\u3051\u305f\u5b89\u5168\u6027\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u306e\u3055\u3089\u306a\u308b\u84c4\u7a4d\u3002<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<p><strong>\u91cd\u8981\u306a\u5f15\u7528\uff1a<\/strong> \u300cCD19 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