{"id":491,"date":"2026-05-05T13:45:03","date_gmt":"2026-05-05T04:45:03","guid":{"rendered":"https:\/\/rmnw.jp\/teams\/?p=491"},"modified":"2026-05-05T13:45:04","modified_gmt":"2026-05-05T04:45:04","slug":"rm06-%e7%ac%ac%e5%85%ad%e7%ab%a0-%e7%a5%9e%e7%b5%8c%e5%86%85%e7%a7%91%e3%83%bb%e8%84%b3%e7%a5%9e%e7%b5%8c%e5%a4%96%e7%a7%91","status":"publish","type":"post","link":"https:\/\/rmnw.jp\/teams\/?p=491","title":{"rendered":"RM06.\u7b2c\u516d\u7ae0 \u795e\u7d4c\u5185\u79d1\u30fb\u8133\u795e\u7d4c\u5916\u79d1"},"content":{"rendered":"\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"RM06.\u7b2c\u516d\u7ae0 \u795e\u7d4c\u5185\u79d1\u30fb\u8133\u795e\u7d4c\u5916\u79d1\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/jCwIigGH0vA?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n\t\t<div class=\"wppdfemb-frame-container-1\" style=\"-webkit-overflow-scrolling:auto;\">\n\t\t\t<iframe class=\"pdfembed-iframe nonfullscreen wppdf-emb-iframe-1\"\n\t\t\t\tsrc=\"https:\/\/rmnw.jp\/teams\/?pdfemb-data=eyJwZGZJRCI6NDkyLCJ1cmwiOiJodHRwczpcL1wvcm1udy5qcFwvdGVhbXNcL3dwLWNvbnRlbnRcL3VwbG9hZHNcLzIwMjZcLzA1XC9STTA2Llx1N2IyY1x1NTE2ZFx1N2FlMC1cdTc5NWVcdTdkNGNcdTUxODVcdTc5ZDFcdTMwZmJcdTgxMzNcdTc5NWVcdTdkNGNcdTU5MTZcdTc5ZDEucGRmIiwiaW5kZXgiOjF9\"\n\t\t\t\t\t\t\t\tdata-pdf-id=\"492\"\n\t\t\t\tdata-pdf-index=\"1\"\n\t\t\t\tstyle=\"border:none;width:100%;max-width:100%;height:100vh;\"\n\t\t\t\tscrolling=\"yes\">\n\t\t\t<\/iframe>\n\t\t<\/div>\n\n\t\t\n\n\n<h1 class=\"wp-block-heading\">\u795e\u7d4c\u5185\u79d1\u30fb\u8133\u795e\u7d4c\u5916\u79d1\u9818\u57df\u306b\u304a\u3051\u308b\u518d\u751f\u533b\u7642\u3068\u5148\u7aef\u6cbb\u7642\uff1a\u5305\u62ec\u7684\u30d6\u30ea\u30fc\u30d5\u30a3\u30f3\u30b0\u8cc7\u6599<\/h1>\n\n\n\n<h2 class=\"wp-block-heading\">\u30a8\u30b0\u30bc\u30af\u30c6\u30a3\u30d6\u30fb\u30b5\u30de\u30ea\u30fc<\/h2>\n\n\n\n<p>\u672c\u8cc7\u6599\u306f\u3001\u795e\u7d4c\u5185\u79d1\u304a\u3088\u3073\u8133\u795e\u7d4c\u5916\u79d1\u9818\u57df\u306b\u304a\u3051\u308b\u518d\u751f\u533b\u7642\u3001\u7d30\u80de\u7642\u6cd5\u3001\u304a\u3088\u3073\u907a\u4f1d\u5b50\u6cbb\u7642\u306e\u6700\u65b0\u52d5\u5411\u3092\u307e\u3068\u3081\u305f\u3082\u306e\u3067\u3042\u308b\u3002\u73fe\u5728\u3001\u810a\u9ac4\u640d\u50b7\uff08SCI\uff09\u3001\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\uff08PD\uff09\u3001\u5916\u50b7\u6027\u8133\u640d\u50b7\uff08TBI\uff09\u3001\u7b4b\u840e\u7e2e\u6027\u5074\u7d22\u786c\u5316\u75c7\uff08ALS\uff09\u3001\u305d\u3057\u3066\u60aa\u6027\u8133\u816b\u760d\u3067\u3042\u308b\u81a0\u82bd\u816b\uff08GBM\uff09\u3092\u5bfe\u8c61\u3068\u3057\u305f\u9769\u65b0\u7684\u306a\u6cbb\u7642\u6cd5\u306e\u958b\u767a\u304c\u6025\u901f\u306b\u9032\u5c55\u3057\u3066\u3044\u308b\u3002<\/p>\n\n\n\n<p>\u7279\u306b\u3001\u65e5\u672c\u56fd\u5185\u3067\u306f\u4e16\u754c\u306b\u5148\u99c6\u3051\u3066\u810a\u9ac4\u640d\u50b7\u6cbb\u7642\u85ac\u300c\u30b9\u30c6\u30df\u30e9\u30c3\u30af\u300d\u3084\u81a0\u82bd\u816b\u6cbb\u7642\u7528\u30a6\u30a4\u30eb\u30b9\u300c\u30c7\u30ea\u30bf\u30af\u30c8\u300d\u304c\u627f\u8a8d\u30fb\u5b9f\u7528\u5316\u3055\u308c\u3066\u304a\u308a\u3001iPS\u7d30\u80de\u3092\u7528\u3044\u305f\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u6cbb\u7642\u306e\u6cbb\u9a13\u7d50\u679c\u3082\u6975\u3081\u3066\u6709\u671b\u306a\u30c7\u30fc\u30bf\u3092\u793a\u3057\u3066\u3044\u308b\u3002\u4e00\u65b9\u3067\u3001ALS\u6cbb\u7642\u306b\u304a\u3051\u308bNurOwn\u306e\u3088\u3046\u306b\u3001\u6cbb\u9a13\u7d50\u679c\u306e\u89e3\u91c8\u3084\u898f\u5236\u5f53\u5c40\u306e\u627f\u8a8d\u3092\u5de1\u3063\u3066\u8ab2\u984c\u304c\u6b8b\u308b\u9818\u57df\u3082\u5b58\u5728\u3059\u308b\u3002\u672c\u8cc7\u6599\u3067\u306f\u3001\u3053\u308c\u3089\u5404\u75be\u60a3\u306b\u304a\u3051\u308b\u4e3b\u8981\u306a\u6cbb\u9a13\u30c7\u30fc\u30bf\u3001\u6cbb\u7642\u30e1\u30ab\u30cb\u30ba\u30e0\u3001\u304a\u3088\u3073\u5e02\u5834\u30fb\u898f\u5236\u72b6\u6cc1\u306b\u3064\u3044\u3066\u8a73\u7d30\u306b\u5206\u6790\u3059\u308b\u3002<\/p>\n\n\n\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. \u810a\u9ac4\u640d\u50b7\uff08SCI\uff09\u306b\u304a\u3051\u308b\u518d\u751f\u533b\u7642<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">\u75ab\u5b66\u3068\u73fe\u72b6<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u767a\u751f\u72b6\u6cc1:<\/strong> \u65e5\u672c\u56fd\u5185\u3067\u306e\u810a\u9ac4\u640d\u50b7\u8005\u6570\u306f\u5e74\u9593\u7d046,200\u540d\uff082018\u5e74\u30c7\u30fc\u30bf\uff09\u3002\u7537\u5973\u6bd4\u306f3:1\u3067\u7537\u6027\u306b\u591a\u304f\u3001\u53d7\u50b7\u539f\u56e0\u306f\u8ee2\u5012\u30fb\u8ee2\u843d\uff0888.1%\uff09\u304c\u6700\u591a\u3067\u3042\u308b\u3002<\/li>\n\n\n\n<li><strong>\u65e2\u5b58\u6cbb\u7642\u306e\u9650\u754c:<\/strong> \u6025\u6027\u671f\u306b\u304a\u3051\u308b\u9ad8\u7528\u91cf\u30e1\u30c1\u30eb\u30d7\u30ec\u30c9\u30cb\u30be\u30ed\u30f3\uff08MPSS\uff09\u7642\u6cd5\u306f\u3001\u6709\u52b9\u6027\u3068\u30ea\u30b9\u30af\u3092\u5de1\u308a\u7c73\u56fd\u8133\u795e\u7d4c\u5916\u79d1\u5b66\u4f1a\uff08AANS\uff09\u7b49\u3067\u8b70\u8ad6\u304c\u5206\u304b\u308c\u3066\u3044\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">\u4e3b\u8981\u306a\u88fd\u54c1\u3068\u6cbb\u9a13\u52d5\u5411<\/h3>\n\n\n\n<p>\u810a\u9ac4\u640d\u50b7\u306b\u5bfe\u3057\u3066\u306f\u3001\u9593\u8449\u7cfb\u5e79\u7d30\u80de\uff08MSC\uff09\u3084iPS\u7d30\u80de\u7531\u6765\u795e\u7d4c\u524d\u99c6\u7d30\u80de\uff08NS\/PC\uff09\u3092\u7528\u3044\u305f\u30a2\u30d7\u30ed\u30fc\u30c1\u304c\u9032\u3093\u3067\u3044\u308b\u3002<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><td>\u88fd\u54c1\u540d\/\u30b3\u30fc\u30c9<\/td><td>\u958b\u767a\u4f01\u696d\/\u6a5f\u95a2<\/td><td>\u7d30\u80de\u7a2e<\/td><td>\u72b6\u6cc1\u30fb\u4e3b\u8981\u30c7\u30fc\u30bf<\/td><\/tr><tr><td><strong>\u30b9\u30c6\u30df\u30e9\u30c3\u30af (STR012)<\/strong><\/td><td>\u30cb\u30d7\u30ed\/\u672d\u5e4c\u533b\u79d1\u5927\u5b66<\/td><td>\u81ea\u5df1\u9aa8\u9ac4\u7531\u6765\u9593\u8449\u7cfb\u5e79\u7d30\u80de<\/td><td>2018\u5e7412\u6708\u306b\u6761\u4ef6\u30fb\u671f\u9650\u4ed8\u627f\u8a8d\u3002\u85ac\u4fa1\u306f\u7d041,500\u4e07\u5186\u3002AIS\u30b0\u30ec\u30fc\u30c9\u306e\u6539\u5584\u738792.3%\u3092\u5831\u544a\uff08Honmou O et al., 2021\uff09\u3002<\/td><\/tr><tr><td><strong>KP8011<\/strong><\/td><td>\u6176\u61c9\u7fa9\u587e\u5927\u5b66\/\u30ad\u30c3\u30bb\u30a4\u85ac\u54c1<\/td><td>iPS\u7d30\u80de\u7531\u6765\u795e\u7d4c\u524d\u99c6\u7d30\u80de<\/td><td>\u4e9c\u6025\u6027\u671f\u60a3\u8005\u3092\u5bfe\u8c61\u3068\u3057\u305f\u81e8\u5e8a\u7814\u7a76\u30022025\u5e743\u6708\u6642\u70b9\u3067\u30c7\u30fc\u30bf\u84c4\u7a4d\u4e2d\u3002<\/td><\/tr><tr><td><strong>AST-OPC1<\/strong><\/td><td>Lineage Cell Therapeutics<\/td><td>ES\u7d30\u80de\u7531\u6765\u30aa\u30ea\u30b4\u30c7\u30f3\u30c9\u30ed\u30b5\u30a4\u30c8\u524d\u99c6\u7d30\u80de<\/td><td>Phase 1\/2a\u8a66\u9a13\u5b9f\u65bd\u3002<\/td><\/tr><tr><td><strong>NSI-566<\/strong><\/td><td>Neuralstem<\/td><td>\u80ce\u5150\u810a\u9ac4\u7531\u6765\u795e\u7d4c\u5e79\u7d30\u80de<\/td><td>\u6162\u6027\u671f\u810a\u9ac4\u640d\u50b7\u3092\u5bfe\u8c61\u3068\u3057\u305fPhase 1\u8a66\u9a13\u3002<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\">\u4f5c\u7528\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u6bd4\u8f03<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>MSC (\u30b9\u30c6\u30df\u30e9\u30c3\u30af\u7b49):<\/strong> BDNF\u3001NGF\u3001HGF\u3001VEGF\u306a\u3069\u306e\u6804\u990a\u56e0\u5b50\u3092\u653e\u51fa\u3057\u3001\u795e\u7d4c\u4fdd\u8b77\u3001\u8840\u7ba1\u65b0\u751f\u4fc3\u9032\u3001\u708e\u75c7\u6291\u5236\u3092\u4ecb\u3057\u3066\u6a5f\u80fd\u56de\u5fa9\u3092\u4fc3\u3059\u3002<\/li>\n\n\n\n<li><strong>NS\/PC (iPS\u7d30\u80de\u7531\u6765\u7b49):<\/strong> \u640d\u50b7\u90e8\u4f4d\u3067\u306e\u518d\u9ac4\u9798\u5316\u3084\u3001\u65b0\u305f\u306a\u795e\u7d4c\u56de\u8def\u306e\u69cb\u7bc9\u3001\u5bbf\u4e3b\u795e\u7d4c\u7d30\u80de\u306e\u4fdd\u8b77\u3092\u76ee\u7684\u3068\u3059\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. \u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\uff08PD\uff09\u3068iPS\u7d30\u80de\u6cbb\u7642<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">\u75be\u60a3\u80cc\u666f<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u60a3\u8005\u6570:<\/strong> \u65e5\u672c\u56fd\u5185\u306e\u60a3\u8005\u6570\u306f\u7d0414.7\u4e07\u4eba\uff082023\u5e74\uff09\u3002\u9ad8\u9f62\u5316\u306b\u4f34\u3044\u30012040\u5e74\u306b\u306f\u4e16\u754c\u7684\u306b\u60a3\u8005\u6570\u304c\u500d\u5897\u3059\u308b\u3068\u4e88\u6e2c\u3055\u308c\u3066\u3044\u308b\u3002<\/li>\n\n\n\n<li><strong>\u6cbb\u7642\u306e\u8ab2\u984c:<\/strong> \u85ac\u7269\u7642\u6cd5\u3067\u306f\u9577\u671f\u670d\u7528\u306b\u3088\u308b\u300c\u30a6\u30a7\u30a2\u30ea\u30f3\u30b0\u30fb\u30aa\u30d5\u300d\u3084\u300c\u65e5\u5185\u5909\u52d5\u300d\u304c\u8ab2\u984c\u3068\u306a\u308a\u3001\u5916\u79d1\u7684\u6cbb\u7642\uff08DBS\uff09\u3082\u3059\u3079\u3066\u306e\u60a3\u8005\u306b\u9069\u5fdc\u3059\u308b\u308f\u3051\u3067\u306f\u306a\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">\u4eac\u90fd\u5927\u5b66\u306b\u3088\u308biPS\u7d30\u80de\u6cbb\u9a13\uff08Phase I\/II\uff09<\/h3>\n\n\n\n<p>\u9ad8\u6a4b\u6df3\u6559\u6388\u3089\u306b\u3088\u308biPS\u7d30\u80de\u7531\u6765\u30c9\u30d1\u30df\u30f3\u795e\u7d4c\u524d\u99c6\u7d30\u80de\u306e\u79fb\u690d\u8a66\u9a13\u304c\u5927\u304d\u306a\u6ce8\u76ee\u3092\u96c6\u3081\u3066\u3044\u308b\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u6cbb\u9a13\u6982\u8981:<\/strong> HLA\u578b\u3092\u5408\u308f\u305b\u305fiPS\u7d30\u80de\u30b9\u30c8\u30c3\u30af\u3092\u4f7f\u7528\u30021,200\u4e07\u500b\u306e\u7d30\u80de\u3092\u88ab\u9a13\u8005\u306e\u7dda\u6761\u4f53\u306b\u79fb\u690d\u3002<\/li>\n\n\n\n<li><strong>\u81e8\u5e8a\u6210\u7e3e\uff08Nature 2025\u767a\u8868\uff09:<\/strong>\n<ul class=\"wp-block-list\">\n<li>\u4e3b\u8981\u8a55\u4fa1\u9805\u76ee\u3067\u3042\u308b\u5b89\u5168\u6027\uff08AE\uff09\u306f\u6982\u306d\u826f\u597d\u3002<\/li>\n\n\n\n<li>MDS-UPDRS Part III\uff08OFF\u6642\uff09\u306e\u30b9\u30b3\u30a2\u304c\u5e73\u574729.5\u30dd\u30a4\u30f3\u30c8\uff0820.4%\uff09\u6539\u5584\u3002<\/li>\n\n\n\n<li>18F-DOPA PET\u691c\u67fb\u306b\u3066\u3001\u88ab\u6bbb\u306e\u30c9\u30d1\u30df\u30f3\u53d6\u308a\u8fbc\u307f\u80fd\u304c\u5e73\u574744.7%\u5897\u52a0\u3002<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u4eca\u5f8c\u306e\u5c55\u958b:<\/strong> 2025\u5e74\u5ea6\u5185\u306e\u627f\u8a8d\u7533\u8acb\u3092\u76ee\u6307\u3057\u3066\u304a\u308a\u3001\u5927\u65e5\u672c\u4f4f\u53cb\u88fd\u85ac\uff08DSP-3077\uff09\u3068\u306e\u9023\u643a\u3082\u9032\u3093\u3067\u3044\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">\u30b0\u30ed\u30fc\u30d0\u30eb\u306a\u7af6\u5408\u72b6\u6cc1<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>BlueRock Therapeutics:<\/strong> iPS\u7d30\u80de\u7531\u6765\u7d30\u80de\u3092\u7528\u3044\u305fPhase I\u8a66\u9a13\u3092\u5b8c\u4e86\u3002\u9ad8\u7528\u91cf\u7fa4\u3067\u306e\u6709\u52b9\u6027\u3092\u78ba\u8a8d\u3002<\/li>\n\n\n\n<li><strong>Aspen Neuroscience (ANPD001):<\/strong> \u81ea\u5df1iPS\u7d30\u80de\u7531\u6765\u306e\u30c9\u30d1\u30df\u30f3\u795e\u7d4c\u3092\u7528\u3044\u305f\u500b\u5225\u5316\u533b\u7642\u30a2\u30d7\u30ed\u30fc\u30c1\u3002<\/li>\n<\/ul>\n\n\n\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. \u5916\u50b7\u6027\u8133\u640d\u50b7\uff08TBI\uff09\u304a\u3088\u3073\u8133\u5352\u4e2d<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">SB623\uff08\u4e00\u822c\u540d\uff1a\u30d0\u30f3\u30c7\u30d5\u30a3\u30c6\u30e0\u30bb\u30eb\uff09<\/h3>\n\n\n\n<p>\u30b5\u30f3\u30d0\u30a4\u30aa\u793e\u304c\u958b\u767a\u4e2d\u306e\u3001Notch-1\u907a\u4f1d\u5b50\u3092\u5c0e\u5165\u3057\u305f\u9aa8\u9ac4\u7531\u6765\u9593\u8449\u7cfb\u5e79\u7d30\u80de\u3067\u3042\u308b\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>STEMTRA\u8a66\u9a13\uff08TBI\u5bfe\u8c61\uff09:<\/strong>\n<ul class=\"wp-block-list\">\n<li>Phase 2\u8a66\u9a13\u306b\u304a\u3044\u3066\u3001Fugl-Meyer Motor Scale\uff08FMMS\uff09\u304c+8.3\u6539\u5584\uff08\u507d\u624b\u8853\u7fa4\u306f+2.3\uff09\u3002<\/li>\n\n\n\n<li>48\u9031\u6642\u70b9\u3067\u3082\u52b9\u679c\u304c\u6301\u7d9a\u3057\u3066\u304a\u308a\u3001Class I\u30a8\u30d3\u30c7\u30f3\u30b9\u3068\u3057\u3066\u306e\u8a55\u4fa1\u3092\u5f97\u3066\u3044\u308b\u3002<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u898f\u5236\u72b6\u6cc1:<\/strong> \u65e5\u672c\u56fd\u5185\u30672024\u5e747\u6708\u306b\u6761\u4ef6\u30fb\u671f\u9650\u4ed8\u627f\u8a8d\u3092\u7533\u8acb\u3002RMAT\u6307\u5b9a\uff08\u7c73\u56fdFDA\uff09\u3082\u53d7\u3051\u3066\u3044\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">MultiStem\uff08HLCM051\uff09<\/h3>\n\n\n\n<p>\u30d8\u30ea\u30aa\u30b9\u793e\u304c\u958b\u767a\u3092\u9032\u3081\u3066\u3044\u305f\u9aa8\u9ac4\u7531\u6765\u591a\u80fd\u6027\u6210\u4f53\u524d\u99c6\u7d30\u80de\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>TREASURE\u8a66\u9a13\uff08\u6025\u6027\u671f\u8133\u6897\u585e\u5bfe\u8c61\uff09:<\/strong> 206\u4f8b\u3092\u5bfe\u8c61\u3068\u3057\u305fPhase 2\/3\u8a66\u9a13\u3002\u4e3b\u8981\u8a55\u4fa1\u9805\u76ee\u306e\u300cExcellent Outcome\u300d\u3067\u306f\u7d71\u8a08\u7684\u6709\u610f\u7fa9\u5dee\u306b\u81f3\u3089\u306a\u304b\u3063\u305f\u304c\u3001\u30b5\u30d6\u30b0\u30eb\u30fc\u30d7\u89e3\u6790\u3067\u53ef\u80fd\u6027\u3092\u793a\u5506\u3002<\/li>\n\n\n\n<li><strong>\u73fe\u72b6:<\/strong> \u958b\u767a\u5143\u306eAthersys\u793e\u304cChapter 11\u3092\u7533\u8acb\uff082024\u5e74\uff09\u3059\u308b\u306a\u3069\u3001\u4e8b\u696d\u7d99\u7d9a\u306b\u8ab2\u984c\u3002<\/li>\n<\/ul>\n\n\n\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. \u7b4b\u840e\u7e2e\u6027\u5074\u7d22\u786c\u5316\u75c7\uff08ALS\uff09<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">NurOwn\uff08MSC-NTF\u7642\u6cd5\uff09<\/h3>\n\n\n\n<p>BrainStorm Cell Therapeutics\u793e\u306b\u3088\u308b\u3001\u795e\u7d4c\u6804\u990a\u56e0\u5b50\uff08NTF\uff09\u3092\u9ad8\u767a\u73fe\u3059\u308b\u3088\u3046\u8a98\u5c0e\u3057\u305f\u81ea\u5df1MSC\u3092\u7528\u3044\u305f\u6cbb\u7642\u6cd5\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u6cbb\u9a13\u7d50\u679c:<\/strong> Phase 3\u8a66\u9a13\uff082020\u5e74\u767a\u8868\uff09\u3067\u306f\u3001ALSFRS-R\u306e\u30ec\u30b9\u30dd\u30f3\u30c0\u30fc\u7387\u306b\u304a\u3044\u3066\u507d\u85ac\u7fa4\u3068\u306e\u6709\u610f\u5dee\u3092\u793a\u305b\u306a\u304b\u3063\u305f\uff0834.7% vs 27.7%\uff09\u3002\u3057\u304b\u3057\u3001\u9032\u884c\u306e\u9045\u3044\u30b5\u30d6\u30b0\u30eb\u30fc\u30d7\u3067\u306f\u6709\u671b\u306a\u50be\u5411\uff08p=0.052\uff09\u304c\u898b\u3089\u308c\u305f\u3002<\/li>\n\n\n\n<li><strong>\u898f\u5236\u5f53\u5c40\u3068\u306e\u5bfe\u7acb:<\/strong> 2023\u5e74\u306eFDA\u8aee\u554f\u59d4\u54e1\u4f1a\u3067\u306f\u3001\u5727\u5012\u7684\u591a\u6570\uff0817\u5bfe1\uff09\u3067\u627f\u8a8d\u652f\u6301\u304c\u5f97\u3089\u308c\u305a\u3002\u73fe\u5728\u3001\u65b0\u305f\u306aPhase 3b\u8a66\u9a13\uff08ENDURANCE\uff09\u304c\u9032\u884c\u4e2d\u3002<\/li>\n<\/ul>\n\n\n\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. \u60aa\u6027\u8133\u816b\u760d\uff08\u81a0\u82bd\u816b\uff1aGBM\uff09\u3068\u30a6\u30a4\u30eb\u30b9\u7642\u6cd5<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">G47\u0394\uff08\u30c7\u30ea\u30bf\u30af\u30c8\uff09<\/h3>\n\n\n\n<p>\u6771\u4eac\u5927\u5b66\u306e\u6238\u7530\u6b63\u535a\u6559\u6388\u3089\u306b\u3088\u3063\u3066\u958b\u767a\u3055\u308c\u305f\u3001\u7b2c3\u4e16\u4ee3\u304c\u3093\u6cbb\u7642\u7528\u30d8\u30eb\u30da\u30b9\u30a6\u30a4\u30eb\u30b9\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u627f\u8a8d\u72b6\u6cc1:<\/strong> 2021\u5e746\u6708\u306b\u60aa\u6027\u795e\u7d4c\u81a0\u816b\u3092\u5bfe\u8c61\u3068\u3057\u3066\u56fd\u5185\u627f\u8a8d\u3002<\/li>\n\n\n\n<li><strong>\u4f5c\u7528\u6a5f\u5e8f:<\/strong> \u816b\u760d\u7d30\u80de\u5185\u3067\u7279\u7570\u7684\u306b\u5897\u6b96\u3057\u3066\u7d30\u80de\u3092\u7834\u58ca\u3059\u308b\u3068\u540c\u6642\u306b\u3001\u6297\u816b\u760d\u514d\u75ab\u3092\u6d3b\u6027\u5316\u3059\u308b\u3002<\/li>\n\n\n\n<li><strong>Phase 2\u8a66\u9a13\uff08Todo T et al., 2022\uff09:<\/strong>\n<ul class=\"wp-block-list\">\n<li><strong>1\u5e74\u751f\u5b58\u7387:<\/strong> 84.2%\uff08\u30d2\u30b9\u30c8\u30ea\u30ab\u30eb\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u306e\u7d0415%\u3092\u5927\u5e45\u306b\u4e0a\u56de\u308b\uff09\u3002<\/li>\n\n\n\n<li><strong>\u751f\u5b58\u671f\u9593\u4e2d\u592e\u5024 (OS):<\/strong> 20.2\u30f6\u6708\u3002<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u85ac\u4fa1:<\/strong> 1\u56de\u3042\u305f\u308a\u7d04143\u4e07\u5186\uff08\u6a19\u6e96\u7684\u306a6\u56de\u6295\u4e0e\u3067\u7d04858\u4e07\u5186\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. \u52a0\u9f62\u9ec4\u6591\u5909\u6027\uff08AMD\uff09<\/h2>\n\n\n\n<p>iPS\u7d30\u80de\u3092\u7528\u3044\u305f\u4e16\u754c\u521d\u306e\u81e8\u5e8a\u5fdc\u7528\u304c\u884c\u308f\u308c\u305f\u9818\u57df\u3067\u3042\u308b\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u6b74\u53f2\u7684\u7d4c\u7def:<\/strong> 2014\u5e74\u306b\u9ad8\u6a4b\u653f\u4ee3\u535a\u58eb\uff08\u7406\u7814\/CDB\uff09\u3089\u304c\u81ea\u5df1iPS\u7531\u6765RPE\u7d30\u80de\u30b7\u30fc\u30c8\u306e\u79fb\u690d\u3092\u5b9f\u65bd\u3002<\/li>\n\n\n\n<li><strong>\u6700\u65b0\u52d5\u5411:<\/strong> \u4ed6\u5bb6\uff08HLA\u5408\u81f4\uff09iPS\u7d30\u80de\u3092\u7528\u3044\u305f\u7814\u7a76\u3078\u79fb\u884c\u3002iPS-RPE\u30b9\u30c8\u30ea\u30c3\u30d7\u3092\u7528\u3044\u305f\u8a66\u9a13\u306b\u304a\u3044\u3066\u3001252\u9031\u306b\u304a\u3088\u3076\u9577\u671f\u306e\u5b89\u5168\u6027\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u308b\uff08Sakai et al., 2025\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u7d50\u8ad6<\/h2>\n\n\n\n<p>\u795e\u7d4c\u30fb\u8133\u5916\u79d1\u9818\u57df\u306e\u518d\u751f\u533b\u7642\u306f\u3001\u7814\u7a76\u6bb5\u968e\u304b\u3089\u5b9f\u7528\u5316\u306e\u30d5\u30a7\u30fc\u30ba\u3078\u3068\u5b8c\u5168\u306b\u79fb\u884c\u3057\u3066\u3044\u308b\u3002\u7279\u306b\u65e5\u672c\u306f\u300c\u6761\u4ef6\u30fb\u671f\u9650\u4ed8\u627f\u8a8d\u5236\u5ea6\u300d\u3092\u80cc\u666f\u306b\u3001\u810a\u9ac4\u640d\u50b7\u3084\u8133\u816b\u760d\u306e\u5206\u91ce\u3067\u4e16\u754c\u3092\u30ea\u30fc\u30c9\u3059\u308b\u6210\u679c\u3092\u51fa\u3057\u3066\u3044\u308b\u3002\u4eca\u5f8c\u306f\u3001iPS\u7d30\u80de\u7531\u6765\u6cbb\u7642\u306e\u85ac\u4e8b\u627f\u8a8d\u3068\u3001\u9ad8\u984d\u306a\u6cbb\u7642\u8cbb\u306b\u5bfe\u3059\u308b\u533b\u7642\u7d4c\u6e08\u7684\u306a\u8b70\u8ad6\u304c\u7126\u70b9\u3068\u306a\u308b\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"\u795e\u7d4c\u5185\u79d1\u30fb\u8133\u795e\u7d4c\u5916\u79d1\u9818\u57df\u306b\u304a\u3051\u308b\u518d\u751f\u533b\u7642\u3068\u5148\u7aef\u6cbb\u7642\uff1a\u5305\u62ec\u7684\u30d6\u30ea\u30fc\u30d5\u30a3\u30f3\u30b0\u8cc7\u6599 \u30a8\u30b0\u30bc\u30af\u30c6\u30a3\u30d6\u30fb\u30b5\u30de\u30ea\u30fc \u672c\u8cc7\u6599\u306f\u3001\u795e\u7d4c\u5185\u79d1\u304a\u3088\u3073\u8133\u795e\u7d4c\u5916\u79d1\u9818\u57df\u306b\u304a\u3051\u308b\u518d\u751f\u533b\u7642\u3001\u7d30\u80de\u7642\u6cd5\u3001\u304a\u3088\u3073\u907a\u4f1d\u5b50\u6cbb\u7642\u306e\u6700\u65b0\u52d5\u5411\u3092\u307e\u3068\u3081\u305f\u3082\u306e\u3067\u3042\u308b\u3002\u73fe [&hellip;]","protected":false},"author":1,"featured_media":493,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[16,32,33,25],"tags":[],"class_list":["post-491","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-textbook","category-32","category-33","category-25"],"jetpack_featured_media_url":"https:\/\/rmnw.jp\/teams\/wp-content\/uploads\/2026\/05\/\u518d\u751f\u533b\u7642\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u30e6\u30fc\u30b6\u30fc-69f975b0d5814.png","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/rmnw.jp\/teams\/index.php?rest_route=\/wp\/v2\/posts\/491","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/rmnw.jp\/teams\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/rmnw.jp\/teams\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/rmnw.jp\/teams\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/rmnw.jp\/teams\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=491"}],"version-history":[{"count":1,"href":"https:\/\/rmnw.jp\/teams\/index.php?rest_route=\/wp\/v2\/posts\/491\/revisions"}],"predecessor-version":[{"id":494,"href":"https:\/\/rmnw.jp\/teams\/index.php?rest_route=\/wp\/v2\/posts\/491\/revisions\/494"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/rmnw.jp\/teams\/index.php?rest_route=\/wp\/v2\/media\/493"}],"wp:attachment":[{"href":"https:\/\/rmnw.jp\/teams\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=491"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/rmnw.jp\/teams\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=491"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/rmnw.jp\/teams\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=491"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}