{"id":842,"date":"2025-08-13T11:20:57","date_gmt":"2025-08-13T02:20:57","guid":{"rendered":"https:\/\/rmnw.jp\/?p=842"},"modified":"2025-09-30T14:37:49","modified_gmt":"2025-09-30T05:37:49","slug":"%e7%be%8e%e5%ae%b9%e7%9a%ae%e8%86%9a%e7%a7%91%e5%8c%bb%e5%b8%ab%e5%90%91%e3%81%91%e9%a6%99%e7%b2%a7%e5%93%81%e5%90%84%e7%a8%ae%e3%82%ac%e3%82%a4%e3%83%89","status":"publish","type":"post","link":"https:\/\/rmnw.jp\/?p=842","title":{"rendered":"D37.\u7f8e\u5bb9\u76ae\u819a\u79d1\u5b66\u3000\u9999\u7ca7\u54c1\u30ac\u30a4\u30c9"},"content":{"rendered":"\n<figure class=\"wp-block-audio\"><audio controls src=\"https:\/\/rmnw.jp\/wp-content\/uploads\/2025\/09\/D37.\u7f8e\u5bb9\u76ae\u819a\u79d1\u5b66-\u9999\u7ca7\u54c1\u30ac\u30a4\u30c9.mp3\"><\/audio><\/figure>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"D37 \u7f8e\u5bb9\u76ae\u819a\u79d1\u5b66 \u9999\u7ca7\u54c1\u30ab\u3099\u30a4\u30c8\u3099\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/9Tzra7spttU?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n<a href=\"https:\/\/rmnw.jp\/wp-content\/uploads\/2025\/09\/D37.\u7f8e\u5bb9\u76ae\u819a\u79d1\u5b66-\u9999\u7ca7\u54c1\u30ac\u30a4\u30c9.pdf\" class=\"pdfemb-viewer\" style=\"\" data-width=\"max\" data-height=\"max\" data-toolbar=\"bottom\" data-toolbar-fixed=\"on\">D37.\u7f8e\u5bb9\u76ae\u819a\u79d1\u5b66-\u9999\u7ca7\u54c1\u30ac\u30a4\u30c9<\/a>\n\n\n<h1 class=\"wp-block-heading\">\u7f8e\u5bb9\u76ae\u819a\u79d1\u533b\u306e\u305f\u3081\u306e\u9999\u7ca7\u54c1\u30ab\u30c6\u30b4\u30ea\u5225\u30ac\u30a4\u30c9<\/h1>\n\n\n\n<h2 class=\"wp-block-heading\">1. \u30b9\u30ad\u30f3\u30b1\u30a2\u5316\u7ca7\u54c1\uff08\u4fdd\u6e7f\u30fb\u6d17\u6d44\u30fb\u89d2\u8cea\u30b1\u30a2\u30fb\u7f8e\u767d\u306a\u3069\uff09<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">\u4e3b\u8981\u6210\u5206\u3068\u4f5c\u7528\u6a5f\u5e8f<\/h3>\n\n\n\n<p><strong>\u4fdd\u6e7f\u5264:<\/strong> \u4fdd\u6e7f\u5316\u7ca7\u54c1\u306b\u306f\u30d2\u30a2\u30eb\u30ed\u30f3\u9178\u3001\u30b0\u30ea\u30bb\u30ea\u30f3\u306a\u3069\u306e\u30d2\u30e5\u30fc\u30e1\u30af\u30bf\u30f3\u30c8\uff08\u5438\u6e7f\u5264\uff09\u3001\u30ef\u30bb\u30ea\u30f3\u3084\u30df\u30cd\u30e9\u30eb\u30aa\u30a4\u30eb\u3001\u30b7\u30ea\u30b3\u30fc\u30f3\uff08\u30b8\u30e1\u30c1\u30b3\u30f3\uff09\u306a\u3069\u306e\u30aa\u30af\u30eb\u30fc\u30b7\u30d6\uff08\u9589\u585e\u5264\uff09\u3001\u30bb\u30e9\u30df\u30c9\u3084\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3001\u8102\u80aa\u9178\u306a\u3069\u306e\u30a8\u30e2\u30ea\u30a8\u30f3\u30c8\uff08\u67d4\u8edf\u5264\uff09\u304c\u542b\u307e\u308c\u307e\u3059\u3002\u30d2\u30e5\u30fc\u30e1\u30af\u30bf\u30f3\u30c8\u306f\u89d2\u8cea\u5c64\u306b\u6c34\u5206\u3092\u5f15\u304d\u5bc4\u305b\u4fdd\u6301\u3057\u3001\u30aa\u30af\u30eb\u30fc\u30b7\u30d6\u306f\u76ae\u819a\u8868\u9762\u306b\u758e\u6c34\u6027\u306e\u819c\u3092\u4f5c\u308a\u6c34\u5206\u84b8\u6563\u3092\u9632\u304e\u307e\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5849435\/#:~:text=Petroleum%20is%20a%20mineral%20oil,16\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5849435\/#:~:text=Petrolatum%20is%20the%20most%20effective,16\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002\u30a8\u30e2\u30ea\u30a8\u30f3\u30c8\u306f\u89d2\u8cea\u7d30\u80de\u9593\u8102\u8cea\u3092\u88dc\u3044\u3001\u808c\u3092\u67d4\u3089\u304b\u304f\u6ed1\u3089\u304b\u306b\u3057\u307e\u3059\u3002\u4f8b\u3048\u3070\u30ef\u30bb\u30ea\u30f3\u306f5%\u4ee5\u4e0a\u3067\u7d4c\u8868\u76ae\u6c34\u5206\u84b8\u6563(TEWL)\u309298%\u3082\u4f4e\u6e1b\u3067\u304d\u308b\u5f37\u529b\u306a\u30aa\u30af\u30eb\u30fc\u30b7\u30d6\u3067\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5849435\/#:~:text=Petroleum%20is%20a%20mineral%20oil,16\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5849435\/#:~:text=Petrolatum%20is%20the%20most%20effective,16\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002\u30bb\u30e9\u30df\u30c9\u7b49\u306e\u751f\u4f53\u985e\u4f3c\u8102\u8cea\u306f\u30d0\u30ea\u30a2\u6a5f\u80fd\u56de\u5fa9\u3092\u52a9\u3051\u307e\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5849435\/#:~:text=Ointments%20are%20preferred%20over%20creams%2C,Gutman%20et%20al%20103\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002\u3053\u308c\u3089\u6210\u5206\u306e\u7d44\u307f\u5408\u308f\u305b\u306b\u3088\u308a\u3001\u4fdd\u6e7f\u5264\u306f\u76ae\u819a\u30d0\u30ea\u30a2\u3092\u4fee\u5fa9\u30fb\u5f37\u5316\u3057\u5916\u7684\u523a\u6fc0\u304b\u3089\u808c\u3092\u5b88\u308a\u307e\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5849435\/#:~:text=Frequent%20moisturizer%20application%20provides%20protection,76\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5849435\/#:~:text=Ointments%20are%20preferred%20over%20creams%2C,Gutman%20et%20al%20103\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002\u7279\u306b\u8102\u8cea\u3092\u8c4a\u5bcc\u306b\u542b\u3080\u4fdd\u6e7f\u5264\u306f\u30d0\u30ea\u30a2\u6a5f\u80fd\u6539\u5584\u52b9\u679c\u304c\u9ad8\u304f\u3001\u63a5\u89e6\u76ae\u819a\u708e\u3084\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u3067\u3082\u7a4d\u6975\u7684\u306b\u63a8\u5968\u3055\u308c\u307e\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5849435\/#:~:text=Frequent%20moisturizer%20application%20provides%20protection,76\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5849435\/#:~:text=lipids%2C%20including%20ceramides%2C%20may%20accelerate,Gutman%20et%20al79\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002<\/p>\n\n\n\n<p><strong>\u6d17\u6d44\u5264:<\/strong> \u30af\u30ec\u30f3\u30b8\u30f3\u30b0\u6599\u3084\u6d17\u9854\u6599\u306e\u4e3b\u6210\u5206\u306f\u754c\u9762\u6d3b\u6027\u5264\u3067\u3059\u3002\u77f3\u9e78\uff08\u9ad8\u7d1a\u8102\u80aa\u9178\u5869\uff09\u3084\u786b\u9178\u7cfb\u754c\u9762\u6d3b\u6027\u5264\uff08SLS\u306a\u3069\uff09\u306f\u6ce1\u7acb\u3061\u6d17\u6d44\u529b\u304c\u9ad8\u3044\u4e00\u65b9\u3001\u76ae\u819a\u306e\u30bf\u30f3\u30d1\u30af\u3084\u8102\u8cea\u3082\u596a\u3044\u304c\u3061\u3067\u3059<a href=\"https:\/\/www.mdpi.com\/1420-3049\/27\/6\/2010#:~:text=which%20leads%20to%20the%20lowering,that%20the%20science%20behind%20cleansers\" target=\"_blank\" rel=\"noreferrer noopener\">mdpi.com<\/a><a href=\"https:\/\/www.mdpi.com\/1420-3049\/27\/6\/2010#:~:text=former%20tends%20to%20negatively%20affect,s%29%20in%20skin%20cleansers%E2%80%94and\" target=\"_blank\" rel=\"noreferrer noopener\">mdpi.com<\/a>\u3002\u8fd1\u5e74\u306f\u5408\u6210\u6d17\u5264\uff08\u30b7\u30f3\u30c7\u30c3\u30c8\uff09\u3084\u30a2\u30df\u30ce\u9178\u7cfb\u30fb\u4e21\u6027\u754c\u9762\u6d3b\u6027\u5264\uff08\u30b3\u30ab\u30df\u30c9\u30d7\u30ed\u30d4\u30eb\u30d9\u30bf\u30a4\u30f3\u7b49\uff09\u3092\u7528\u3044\u3001\u76ae\u819apH\u306b\u8fd1\u3044\u5f31\u9178\u6027\u51e6\u65b9\u3068\u3059\u308b\u3053\u3068\u3067<strong>\u30de\u30a4\u30eb\u30c9\u306a\u6d17\u6d44<\/strong>\u3068\u30d0\u30ea\u30a2\u4fdd\u8b77\u3092\u4e21\u7acb\u3057\u3066\u3044\u307e\u3059<a href=\"https:\/\/www.mdpi.com\/1420-3049\/27\/6\/2010#:~:text=which%20leads%20to%20the%20lowering,understood%20by%20both%20formulators%20and\" target=\"_blank\" rel=\"noreferrer noopener\">mdpi.com<\/a><a href=\"https:\/\/www.mdpi.com\/1420-3049\/27\/6\/2010#:~:text=types%3A%20soap,s%29%20in%20skin%20cleansers%E2%80%94and\" target=\"_blank\" rel=\"noreferrer noopener\">mdpi.com<\/a>\u3002\u6d17\u6d44\u306e\u6a5f\u5e8f\u306f\u754c\u9762\u6d3b\u6027\u5264\u304c\u76ae\u8102\u3084\u6c5a\u308c\u3092\u4e73\u5316\u30fb\u53ef\u6eb6\u5316\u3057\u3001\u3059\u3059\u304e\u3067\u9664\u53bb\u3059\u308b\u3053\u3068\u3067\u3059\u3002\u4e00\u65b9\u3001\u9ad8pH\u306e\u77f3\u9e78\u306f\u89d2\u5c64\u30bf\u30f3\u30d1\u30af\u306e\u81a8\u6f64\u30fb\u8102\u8cea\u6eb6\u51fa\u3092\u5f15\u304d\u8d77\u3053\u3057\u30d0\u30ea\u30a2\u7834\u58ca\u3084\u4e7e\u71e5\u30fb\u523a\u6fc0\u3092\u62db\u304f\u305f\u3081\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059<a href=\"https:\/\/www.mdpi.com\/1420-3049\/27\/6\/2010#:~:text=former%20tends%20to%20negatively%20affect,s%29%20in%20skin%20cleansers%E2%80%94and\" target=\"_blank\" rel=\"noreferrer noopener\">mdpi.com<\/a><a href=\"https:\/\/www.mdpi.com\/1420-3049\/27\/6\/2010#:~:text=stressors%20can%20impede%20the%20skin%E2%80%99s,2\" target=\"_blank\" rel=\"noreferrer noopener\">mdpi.com<\/a>\u3002\u6700\u8fd1\u306e\u6d17\u6d44\u5264\u306b\u306f\u30b0\u30ea\u30bb\u30ea\u30f3\u306a\u3069\u4fdd\u6e7f\u6210\u5206\u3092\u914d\u5408\u3057\u3001\u300c\u6d17\u3044\u3059\u304e\u300d\u306b\u3088\u308b\u3064\u3063\u3071\u308a\u611f\u3092\u6e1b\u3089\u3059\u5de5\u592b\u3082\u306a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u89d2\u8cea\u30b1\u30a2\u5264:<\/strong> \u53e4\u3044\u89d2\u8cea\u3092\u9664\u53bb\u3059\u308b\u89d2\u8cea\u30b1\u30a2\u3068\u3057\u3066<strong>\u7269\u7406\u7684\u30b9\u30af\u30e9\u30d6<\/strong>\uff08\u30b7\u30e5\u30ac\u30fc\u30b9\u30af\u30e9\u30d6\u3001\u5408\u6210\u6a39\u8102\u30d3\u30fc\u30ba\u7b49\uff09\u3084\u30d4\u30fc\u30ea\u30f3\u30b0\u30b8\u30a7\u30eb\u306e\u4ed6\u3001<strong>\u5316\u5b66\u7684\u30a8\u30af\u30b9\u30d5\u30a9\u30ea\u30a8\u30f3\u30c8<\/strong>\u304c\u5e83\u304f\u4f7f\u308f\u308c\u307e\u3059\u3002\u03b1-\u30d2\u30c9\u30ed\u30ad\u30b7\u9178(AHA\u3001\u4f8b\uff1a\u30b0\u30ea\u30b3\u30fc\u30eb\u9178\u30fb\u4e73\u9178)\u3084\u03b2-\u30d2\u30c9\u30ed\u30ad\u30b7\u9178(BHA\u3001\u4f8b\uff1a\u30b5\u30ea\u30c1\u30eb\u9178)\u306f\u89d2\u8cea\u7d30\u80de\u9593\u306e\u7d50\u5408\u3092\u5f31\u3081\u3001\u89d2\u8cea\u306e\u5265\u96e2\u3068\u30bf\u30fc\u30f3\u30aa\u30fc\u30d0\u30fc\u4fc3\u9032\u3092\u3082\u305f\u3089\u3057\u307e\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11268769\/#:~:text=analysis%20reveals%20a%20nuanced%20understanding,dermatology%2C%20emphasizing%20the%20necessity%20for\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11268769\/#:~:text=AHAs%20have%20been%20shown%20to,several%20factors%2C%20including%20formulation%2C%20concentration\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002AHA\u306f\u6c34\u6eb6\u6027\u3067\u8868\u76ae\u306b\u4f5c\u7528\u3057\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u7523\u751f\u4fc3\u9032\u3084\u771f\u76ae\u306e\u30ea\u30e2\u30c7\u30ea\u30f3\u30b0\u52b9\u679c\u3082\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11268769\/#:~:text=applications%20of%20AHAs%2C%20particularly%20in,Regulatory%20compliance%20is\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11268769\/#:~:text=analysis%20reveals%20a%20nuanced%20understanding,dermatology%2C%20emphasizing%20the%20necessity%20for\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002BHA\uff08\u30b5\u30ea\u30c1\u30eb\u9178\uff09\u306f\u8102\u6eb6\u6027\u3067\u6bdb\u5b54\u5185\u3078\u6d78\u900f\u3057\u3001\u89d2\u6813\u306e\u6eb6\u89e3\u3084\u6297\u708e\u75c7\u4f5c\u7528\u3092\u793a\u3059\u305f\u3081\u3001\u306b\u304d\u3073\u808c\u5411\u3051\u306b\u6709\u52b9\u3067\u3059\u3002\u9175\u7d20\u7cfb\u89d2\u8cea\u5206\u89e3\u5264\uff08\u30d1\u30d1\u30a4\u30f3\u7b49\uff09\u306f\u30bf\u30f3\u30d1\u30af\u8cea\u5206\u89e3\u3067\u89d2\u8cea\u3092\u67d4\u8edf\u306b\u3057\u307e\u3059\u3002\u3053\u308c\u3089\u89d2\u8cea\u30b1\u30a2\u6210\u5206\u306b\u3088\u308a\u3001\u3056\u3089\u3064\u304d\u6539\u5584\u3084\u304f\u3059\u307f\u9664\u53bb\u3001\u6bdb\u7a74\u8a70\u307e\u308a\u306e\u8efd\u6e1b\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u7f8e\u767d\u6709\u52b9\u6210\u5206:<\/strong> \u808c\u306e\u7f8e\u767d\u30fb\u8272\u8abf\u6539\u5584\u3092\u76ee\u7684\u3068\u3057\u305f\u6210\u5206\u306b\u306f\u3001<strong>\u30e1\u30e9\u30cb\u30f3\u751f\u6210\u6291\u5236<\/strong>\u4f5c\u7528\u3092\u6301\u3064\u3082\u306e\u304c\u591a\u3044\u3067\u3059\u3002\u4ee3\u8868\u7684\u306a\u306e\u306f\u30c1\u30ed\u30b7\u30ca\u30fc\u30bc\u9175\u7d20\u3092\u963b\u5bb3\u3059\u308b\u6210\u5206\u3067\u3001\u30cf\u30a4\u30c9\u30ed\u30ad\u30ce\u30f3\u3084\u305d\u306e\u914d\u7cd6\u4f53\u30a2\u30eb\u30d6\u30c1\u30f3\u3001\u30b3\u30a6\u30b8\u9178\u3001\u30ea\u30f3\u9178\u30a2\u30b9\u30b3\u30eb\u30d3\u30ebMg\uff08\u30d3\u30bf\u30df\u30f3C\u8a98\u5c0e\u4f53\uff09\u3001\u30ea\u30b3\u30ea\u30b9\uff08\u7518\u8349\uff09\u7531\u6765\u30b0\u30e9\u30d6\u30ea\u30b8\u30f3\u306a\u3069\u304c\u6319\u3052\u3089\u308c\u307e\u3059\u3002\u30a2\u30eb\u30d6\u30c1\u30f3\u306f\u30cf\u30a4\u30c9\u30ed\u30ad\u30ce\u30f3\u306e\u5f90\u653e\u6027\u30d7\u30ed\u30c9\u30e9\u30c3\u30b0\u3067\u3001\u30e1\u30e9\u30ce\u30b5\u30a4\u30c8\u5185\u3067\u5f90\u3005\u306b\u30cf\u30a4\u30c9\u30ed\u30ad\u30ce\u30f3\u3092\u653e\u51fa\u3057\u30c1\u30ed\u30b7\u30ca\u30fc\u30bc\u6d3b\u6027\u3092\u6291\u5236\u3057\u307e\u3059<a href=\"https:\/\/jcadonline.com\/study-depigmenting-agents-skin-color\/#:~:text=Arbutin%2C%20%28hydroquinone,be%20safe%20in%20cosmetic%20products\" target=\"_blank\" rel=\"noreferrer noopener\">jcadonline.com<\/a><a href=\"https:\/\/jcadonline.com\/study-depigmenting-agents-skin-color\/#:~:text=The%20release%20of%20hydroquinone%20from,solar%20lentigines%20after%2012%20weeks%E2%80%99\" target=\"_blank\" rel=\"noreferrer noopener\">jcadonline.com<\/a>\u3002\u5b89\u5168\u6027\u306e\u89b3\u70b9\u304b\u3089\u3001\u6b27\u5dde\u3067\u306f\u03b2-\u30a2\u30eb\u30d6\u30c1\u30f3\u306f\u9854\u75282%\u307e\u3067\u914d\u5408\u53ef\u3068\u3055\u308c\u3066\u3044\u307e\u3059<a href=\"https:\/\/jcadonline.com\/study-depigmenting-agents-skin-color\/#:~:text=as%20listed%20in%20Annexure%20III,solar%20lentigines%20after%2012%20weeks%E2%80%99\" target=\"_blank\" rel=\"noreferrer noopener\">jcadonline.com<\/a>\u3002\u30d3\u30bf\u30df\u30f3C\u8a98\u5c0e\u4f53\u3082\u30e1\u30e9\u30cb\u30f3\u5408\u6210\u3092\u59a8\u3052\u3001\u6297\u9178\u5316\u4f5c\u7528\u3067\u65e2\u5b58\u306e\u30e1\u30e9\u30cb\u30f3\u8272\u7d20\u3092\u9084\u5143\u3057\u307e\u3059<a href=\"https:\/\/jcadonline.com\/study-depigmenting-agents-skin-color\/#:~:text=Topical%20stable%20vitamin%20C%2C%20magnesium,Additionally%2C%20ascorbic%20acid%20has%20been\" target=\"_blank\" rel=\"noreferrer noopener\">jcadonline.com<\/a>\u3002\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9\uff08\u30cb\u30b3\u30c1\u30f3\u9178\u30a2\u30df\u30c9\uff09\u306f\u30c1\u30ed\u30b7\u30ca\u30fc\u30bc\u306b\u306f\u76f4\u63a5\u4f5c\u7528\u3057\u307e\u305b\u3093\u304c\u3001\u30e1\u30e9\u30ce\u30bd\u30fc\u30e0\u306e\u30e1\u30e9\u30cb\u30f3\u3092\u30b1\u30e9\u30c1\u30ce\u30b5\u30a4\u30c8\u3078\u53d7\u3051\u6e21\u3059\u7d4c\u8def\u3092\u906e\u65ad\u3059\u308b\u3053\u3068\u3067\u8272\u7d20\u6c88\u7740\u3092\u6539\u5584\u3057\u307e\u3059<a href=\"https:\/\/jcadonline.com\/study-depigmenting-agents-skin-color\/#:~:text=Topical%20niacinamide%20is%20believed%20to,lightening%20effect%20compared%20to%20hydroquinone\" target=\"_blank\" rel=\"noreferrer noopener\">jcadonline.com<\/a>\u300220%\u30a2\u30bc\u30e9\u30a4\u30f3\u9178\u3082\u30c1\u30ed\u30b7\u30ca\u30fc\u30bc\u963b\u5bb3\u3068\u7570\u5e38\u30e1\u30e9\u30ce\u30b5\u30a4\u30c8\u306e\u9078\u629e\u7684\u6291\u5236\u306b\u3088\u308a\u3001\u708e\u75c7\u5f8c\u8272\u7d20\u6c88\u7740\u3084\u809d\u6591\u3092\u6539\u5584\u3057\u307e\u3059<a href=\"https:\/\/jcadonline.com\/study-depigmenting-agents-skin-color\/#:~:text=Azelaic%20acid%20is%20a%20dicarboxylic,12%2C%2013\" target=\"_blank\" rel=\"noreferrer noopener\">jcadonline.com<\/a>\u3002\u305d\u306e\u4ed6\u3001\u30ec\u30c1\u30ce\u30fc\u30eb\uff08\u30d3\u30bf\u30df\u30f3A\u8a98\u5c0e\u4f53\uff09\u306f\u8868\u76ae\u306e\u30bf\u30fc\u30f3\u30aa\u30fc\u30d0\u30fc\u4fc3\u9032\u3068\u30e1\u30e9\u30cb\u30f3\u6392\u51fa\u52b9\u679c\u306b\u3088\u308a\u7f8e\u767d\u306b\u5bc4\u4e0e\u3057\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u4f5c\u7528\u6a5f\u5e8f\u306b\u3088\u308a\u3001\u7f8e\u767d\u6210\u5206\u306f\u30b7\u30df\u30fb\u304f\u3059\u307f\u306e\u4e88\u9632\u3068\u6539\u5584\u306b\u50cd\u304d\u304b\u3051\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u9069\u5fdc\u3068\u4f7f\u7528\u6cd5<\/h3>\n\n\n\n<p><strong>\u4fdd\u6e7f\u30fb\u30af\u30ec\u30f3\u30b8\u30f3\u30b0:<\/strong> \u30b9\u30ad\u30f3\u30b1\u30a2\u306e\u57fa\u672c\u3068\u3057\u3066\u3001\u4e7e\u71e5\u808c\u30fb\u654f\u611f\u808c\u304b\u3089\u8102\u6027\u808c\u307e\u3067\u808c\u8cea\u306b\u5fdc\u3058\u305f\u4fdd\u6e7f\u3068\u6d17\u6d44\u304c\u91cd\u8981\u3067\u3059\u3002\u4fdd\u6e7f\u5264\u306f\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u3084\u63a5\u89e6\u76ae\u819a\u708e\u306e\u60a3\u8005\u306b\u3082\u7b2c\u4e00\u9078\u629e\u3068\u3057\u3066\u63a8\u5968\u3055\u308c\u3001\u30d0\u30ea\u30a2\u6a5f\u80fd\u3092\u6574\u3048\u308b\u3053\u3068\u3067\u7a2e\u3005\u306e\u76ae\u819a\u708e\u306e\u518d\u767a\u4e88\u9632\u306b\u5f79\u7acb\u3061\u307e\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5849435\/#:~:text=Frequent%20moisturizer%20application%20provides%20protection,76\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5849435\/#:~:text=lipids%2C%20including%20ceramides%2C%20may%20accelerate,hydration%20to%20%E2%80%9Clock%20in%E2%80%9D%20moisture\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002\u9069\u5fdc\u3068\u3057\u3066\u306f\u4e7e\u71e5\u808c\u3001\u6e7f\u75b9\u30fb\u76ae\u819a\u708e\u3001\u4e7e\u71e5\u306b\u3088\u308b\u5c0f\u30b8\u30ef\u4e88\u9632\u306a\u3069\u5e83\u7bc4\u3067\u3059\u3002\u5165\u6d74\u5f8c\u3084\u6d17\u9854\u5f8c\u3059\u3050\u3001\u808c\u304c\u5c11\u3057\u6e7f\u3063\u305f\u72b6\u614b\u3067\u4fdd\u6e7f\u5264\u3092\u5857\u5e03\u3059\u308b\u3068\u6c34\u5206\u5c01\u3058\u8fbc\u3081\u52b9\u679c\u304c\u9ad8\u307e\u308a\u307e\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5849435\/#:~:text=Frequent%20moisturizer%20application%20provides%20protection,76\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5849435\/#:~:text=and%20adequate%20skin%20hydration%20is,hydration%20to%20%E2%80%9Clock%20in%E2%80%9D%20moisture\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u30021\u65e51\uff5e3\u56de\u3092\u76ee\u5b89\u306b\u60a3\u90e8\u306b\u7d99\u7d9a\u4f7f\u7528\u3057\u307e\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5849435\/#:~:text=for%20creams%20and%20ointments%20than,1%20and%203%20times%20daily\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002\u6d17\u6d44\u5264\u306f\u30cb\u30ad\u30d3\u3084\u8102\u6f0f\u808c\u3067\u306f\u4f59\u5206\u306a\u76ae\u8102\u3068\u6c5a\u308c\u3092\u843d\u3068\u3057\u6bdb\u7a74\u3092\u6e05\u6f54\u306b\u4fdd\u3064\u76ee\u7684\u3067\u671d\u6669\u4f7f\u7528\u3057\u307e\u3059\u3002\u4e7e\u71e5\u30fb\u654f\u611f\u808c\u3067\u306f\u4f4e\u523a\u6fc0\u306e\u6d17\u6d44\u6599\u30921\u65e51\u56de\u7a0b\u5ea6\u304b\u3064\u77ed\u6642\u9593\u306e\u6d17\u6d44\u306b\u7559\u3081\u3001\u6d17\u6d44\u5f8c\u3059\u307f\u3084\u304b\u306b\u4fdd\u6e7f\u3059\u308b\u3053\u3068\u3067\u808c\u72b6\u614b\u3092\u5b89\u5b9a\u3055\u305b\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u89d2\u8cea\u30b1\u30a2:<\/strong> \u5316\u7ca7\u6c34\u3084\u7f8e\u5bb9\u6db2\u306b\u914d\u5408\u3055\u308c\u305f\u4f4e\u6fc3\u5ea6AHA\uff08\u4f8b\uff1a\u30b0\u30ea\u30b3\u30fc\u30eb\u91785\uff5e10%\uff09\u306f\u6bce\u65e5\uff5e\u9694\u65e5\u306e\u7d99\u7d9a\u4f7f\u7528\u3067\u808c\u306e\u304f\u3059\u307f\u3084\u3056\u3089\u3064\u304d\u3092\u5f90\u3005\u306b\u6539\u5584\u3057\u307e\u3059\u3002\u9ad8\u6fc3\u5ea6AHA\u306b\u3088\u308b\u30d4\u30fc\u30ea\u30f3\u30b0\u306f\u5c02\u9580\u5bb6\u306b\u3088\u308b\u65bd\u8853\u3068\u3057\u30662\uff5e4\u9031\u6bce\u306b\u884c\u3044\u3001\u30cb\u30ad\u30d3\u3084\u809d\u6591\u3001\u5149\u8001\u5316\u306b\u3088\u308b\u7d30\u304b\u3044\u30b7\u30ef\u30fb\u8272\u7d20\u6591\u306e\u6539\u5584\u306b\u9069\u5fdc\u304c\u3042\u308a\u307e\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11268769\/#:~:text=enabling%20effective%20skin%20penetration,10%20%2C%2033\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002\u5bb6\u5ead\u7528\u3067\u306f\u6fc3\u5ea6\u306e\u4f4e\u3044\u30d4\u30fc\u30ea\u30f3\u30b0\u30d1\u30c3\u30c9\u3084\u30b9\u30af\u30e9\u30d6\u3092\u90311-2\u56de\u4f7f\u3046\u7a0b\u5ea6\u306b\u7559\u3081\u3001\u904e\u5ea6\u306e\u6469\u64e6\u3084\u523a\u6fc0\u3092\u907f\u3051\u307e\u3059\u3002\u30b5\u30ea\u30c1\u30eb\u9178\u306f\u30cb\u30ad\u30d3\u808c\u7528\u30c8\u30ca\u30fc\uff08\u4f8b\uff1a\u30b5\u30ea\u30c1\u30eb\u91780.5\uff5e2%\u914d\u5408\uff09\u3068\u3057\u3066\u5e02\u8ca9\u3055\u308c\u3001\u6d17\u9854\u5f8c\u306b\u5857\u5e03\u3059\u308b\u3053\u3068\u3067\u6bdb\u7a74\u8a70\u307e\u308a\u9632\u6b62\u3084\u6297\u708e\u75c7\u52b9\u679c\u3092\u767a\u63ee\u3057\u307e\u3059\u3002\u89d2\u8cea\u30b1\u30a2\u306f\u983b\u5ea6\u3068\u6fc3\u5ea6\u3092\u5b88\u308a\u3001\u523a\u6fc0\u3092\u611f\u3058\u305f\u3089\u4f7f\u7528\u983b\u5ea6\u3092\u6e1b\u3089\u3057\u307e\u3059\u3002\u307e\u305fAHA\u4f7f\u7528\u4e2d\u306f\u7d2b\u5916\u7dda\u611f\u53d7\u6027\u304c\u9ad8\u307e\u308b\u305f\u3081<a href=\"https:\/\/www.fda.gov\/regulatory-information\/search-fda-guidance-documents\/guidance-industry-labeling-cosmetics-containing-alpha-hydroxy-acids#:~:text=Labeling%20for%20Cosmetics%20Containing%20Alpha,that%20this%20increased%20skin\" target=\"_blank\" rel=\"noreferrer noopener\">fda.gov<\/a>\u3001\u65e5\u4e2d\u306f\u65e5\u713c\u3051\u6b62\u3081\u3092\u4f75\u7528\u3059\u308b\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002<\/p>\n\n\n\n<p><strong>\u7f8e\u767d\u30b1\u30a2:<\/strong> 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class=\"wp-block-heading\">\u526f\u4f5c\u7528\u3068\u5b89\u5168\u6027<\/h3>\n\n\n\n<p><strong>\u523a\u6fc0\u6027\u3068\u30a2\u30ec\u30eb\u30ae\u30fc:<\/strong> 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href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5849435\/#:~:text=Keratolytic%20agents%20such%20as%20salicylic,further%20aggravation%20of%20contact%20dermatitis\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002\u30b9\u30af\u30e9\u30d6\u6d17\u9854\u306f\u7269\u7406\u7684\u523a\u6fc0\u3067\u5fae\u5c0f\u306a\u50b7\u3092\u4f5c\u308a\u5f97\u308b\u305f\u3081\u3001\u5f37\u304f\u64e6\u308a\u3059\u304e\u306a\u3044\u6307\u5c0e\u304c\u91cd\u8981\u3067\u3059\u3002\u6d17\u6d44\u5264\u3067\u306f\u30a2\u30eb\u30ab\u30ea\u6027\u77f3\u9e78\u3084\u30e9\u30a6\u30ea\u30eb\u786b\u9178\u7cfb\u306f\u523a\u6fc0\u6027\u304c\u5f37\u304f\u3001\u4e00\u90e8\u3067\u76ae\u819a\u708e\u60aa\u5316\u3084\u4e7e\u71e5\u3092\u62db\u304d\u307e\u3059\u3002\u654f\u611f\u808c\u306b\u306f\u4f4e\u523a\u6fc0\u30fb\u4f4e\u30a2\u30ec\u30eb\u30ae\u30fc\u6027\u51e6\u65b9\uff08\u7121\u9999\u6599\u30fb\u7121\u7740\u8272\u30fb\u4f4e\u9632\u8150\u5264\uff09\u306e\u88fd\u54c1\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u89d2\u8cea\u30b1\u30a2\u5264\u306e\u526f\u4f5c\u7528:<\/strong> 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href=\"https:\/\/www.fda.gov\/regulatory-information\/search-fda-guidance-documents\/guidance-industry-labeling-cosmetics-containing-alpha-hydroxy-acids#:~:text=Labeling%20for%20Cosmetics%20Containing%20Alpha,that%20this%20increased%20skin\" target=\"_blank\" rel=\"noreferrer noopener\">fda.gov<\/a>\u3002\u30ec\u30c1\u30ce\u30fc\u30eb\u3082\u7d2b\u5916\u7dda\u3067\u5206\u89e3\u3057\u3084\u3059\u3044\u305f\u3081\u591c\u9593\u306e\u4f7f\u7528\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u7f8e\u767d\u5264\u306e\u526f\u4f5c\u7528:<\/strong> 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href=\"https:\/\/jcadonline.com\/study-depigmenting-agents-skin-color\/#:~:text=a%20common%20ingredient%20of%20skin,preparations%20may%20cause%20allergic%20contact\" target=\"_blank\" rel=\"noreferrer noopener\">jcadonline.com<\/a>\u3002\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9\u306f\u6bd4\u8f03\u7684\u4f4e\u523a\u6fc0\u3067\u3059\u304c\u3001\u9ad8\u6fc3\u5ea6\u3067\u306f\u4e00\u904e\u6027\u306e\u7d05\u6f6e\u3092\u304d\u305f\u3059\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u3044\u305a\u308c\u306b\u305b\u3088\u3001\u7f8e\u767d\u5264\u4f7f\u7528\u6642\u306f\u808c\u72b6\u614b\u3092\u89b3\u5bdf\u3057\u3001\u523a\u6fc0\u75c7\u72b6\u304c\u51fa\u305f\u5834\u5408\u306f\u983b\u5ea6\u3092\u6e1b\u3089\u3059\u304b\u4f11\u6b62\u3057\u3066\u76ae\u819a\u306e\u56de\u5fa9\u3092\u5f85\u3064\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p><strong>\u5b89\u5168\u6027\u3068\u898f\u5236:<\/strong> 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\u5316\u7ca7\u54c1\u306b\u304a\u3051\u308b\u89d2\u8cea\u30b1\u30a2\u306f\u3001\u300c\u6bce\u65e5\u5c11\u3057\u305a\u3064\u89d2\u8cea\u30aa\u30d5\u3059\u308b\u300d\u30de\u30a4\u30eb\u30c9\u8def\u7dda\u304c\u4e3b\u6d41\u3067\u3059\u3002\u9ad8\u6fc3\u5ea6\u30d4\u30fc\u30ea\u30f3\u30b0\u306f\u533b\u7642\u6a5f\u95a2\u65bd\u8853\u3068\u3057\u3001\u5e02\u8ca9\u54c1\u3067\u306f\u4f4e\u6fc3\u5ea6AHA\u914d\u5408\u306e\u30c8\u30ca\u30fc\u3084\u30d1\u30c3\u30c9\u3001\u9175\u7d20\u6d17\u9854\u30d1\u30a6\u30c0\u30fc\u306a\u3069<strong>\u30bd\u30d5\u30c8\u30d4\u30fc\u30ea\u30f3\u30b0<\/strong>\u88fd\u54c1\u304c\u4eba\u6c17\u3067\u3059\u3002\u7269\u7406\u7684\u30b9\u30af\u30e9\u30d6\u306f\u74b0\u5883\u898f\u5236\u3067\u30d7\u30e9\u30b9\u30c1\u30c3\u30af\u30de\u30a4\u30af\u30ed\u30d3\u30fc\u30ba\u304c\u5404\u56fd\u3067\u7981\u6b62\u3055\u308c\u3001\u4ee3\u66ff\u3068\u3057\u3066\u7cd6\u30fb\u5869\u30fb\u690d\u7269\u7a2e\u5b50\u7531\u6765\u306e\u30b9\u30af\u30e9\u30d6\u7c92\u5b50\u3092\u4f7f\u3063\u305f\u81ea\u7136\u6d3e\u88fd\u54c1\u304c\u5897\u3048\u307e\u3057\u305f\u3002\u3055\u3089\u306b<strong>\u30a8\u30f3\u30b6\u30a4\u30e0\uff08\u9175\u7d20\uff09\u7cfb\u30d4\u30fc\u30ea\u30f3\u30b0<\/strong>\u3084<strong>\u30dd\u30ea\u30d2\u30c9\u30ed\u30ad\u30b7\u9178(PHA)\u306a\u3069\u4f4e\u523a\u6fc0\u306e\u89d2\u8cea\u30b1\u30a2\u6210\u5206\uff08\u30b0\u30eb\u30b3\u30f3\u9178\u306a\u3069\uff09\u3082\u958b\u767a\u3055\u308c\u3001\u654f\u611f\u808c\u3067\u3082\u4f7f\u3048\u308b\u89d2\u8cea\u30b1\u30a2\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u30ec\u30c1\u30ce\u30fc\u30eb\u3084\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9\u3092\u89d2\u8cea\u30b1\u30a2\u3068\u6297\u8001\u5316\u306e\u4e21\u9762\u304b\u3089\u914d\u5408\u3057\u305f\u8907\u5408\u7f8e\u5bb9\u6db2<\/strong>\u3082\u51e6\u65b9\u3055\u308c\u308b\u50be\u5411\u3067\u3059\u3002<\/p>\n\n\n\n<p><strong>\u7f8e\u767d\u5316\u7ca7\u54c1\u306e\u51e6\u65b9\u52d5\u5411:<\/strong> 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class=\"wp-block-heading\">\u81e8\u5e8a\u7684\u6709\u7528\u6027\u3068\u30a8\u30d3\u30c7\u30f3\u30b9<\/h3>\n\n\n\n<p><strong>\u4fdd\u6e7f\u5264:<\/strong> \u4fdd\u6e7f\u5264\u306f\u30b9\u30ad\u30f3\u30b1\u30a2\u306e\u57fa\u672c\u3067\u3042\u308a\u3001<strong>\u81e8\u5e8a\u7684\u6709\u7528\u6027\u304c\u78ba\u7acb<\/strong>\u3057\u3066\u3044\u307e\u3059\u3002\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u3067\u306f\u4fdd\u6e7f\u5264\u306e\u7d99\u7d9a\u4f7f\u7528\u306b\u3088\u308a\u76ae\u819a\u30d0\u30ea\u30a2\u6a5f\u80fd\u304c\u6539\u5584\u3057\u3001\u5897\u60aa\u5bdb\u89e3\u3092\u7e70\u308a\u8fd4\u3059\u75c5\u614b\u306e\u5b89\u5b9a\u5316\u3084\u30b9\u30c6\u30ed\u30a4\u30c9\u5916\u7528\u5264\u306e\u6e1b\u91cf\u304c\u53ef\u80fd\u306b\u306a\u308b\u3068\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u304c\u3042\u308a\u307e\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5849435\/#:~:text=Keratolytic%20agents%20such%20as%20salicylic,further%20aggravation%20of%20contact%20dermatitis\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5849435\/#:~:text=reduced%20trans,further%20aggravation%20of%20contact%20dermatitis\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002\u5b9f\u969b\u30012018\u5e74\u306e\u5831\u544a\u3067\u306f\u5c3f\u7d20\u542b\u6709\u4fdd\u6e7f\u5264\u304c\u6210\u4eba\u30a2\u30c8\u30d4\u30fc\u60a3\u8005\u306e\u75c7\u72b6\u30b9\u30b3\u30a2(SCORAD)\u3092\u6709\u610f\u306b\u6539\u5584\u3057\u305f\u3068\u306e\u30e1\u30bf\u89e3\u6790\u7d50\u679c\u304c\u793a\u3055\u308c\u3001\u7279\u306b\u30d0\u30ea\u30a2\u6a5f\u80fd\u6307\u6a19\u306eTEWL\u4f4e\u4e0b\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5849435\/#:~:text=Keratolytic%20agents%20such%20as%20salicylic,further%20aggravation%20of%20contact%20dermatitis\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002\u63a5\u89e6\u76ae\u819a\u708e\u306e\u4e88\u9632\u306b\u3082\u65e5\u5e38\u7684\u306a\u4fdd\u6e7f\u304c\u6709\u52b9\u3067\u3001\u300c\u983b\u56de\u306e\u4fdd\u6e7f\u5857\u5e03\u304c\u76ae\u819a\u30d0\u30ea\u30a2\u3092\u5f37\u5316\u3057\u523a\u6fc0\u7269\u8cea\u304b\u3089\u76ae\u819a\u3092\u4fdd\u8b77\u3059\u308b\u300d\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5849435\/#:~:text=Frequent%20moisturizer%20application%20provides%20protection,76\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5849435\/#:~:text=lipids%2C%20including%20ceramides%2C%20may%20accelerate,Gutman%20et%20al79\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002\u4e00\u65b9\u3001\u4fdd\u6e7f\u6210\u5206\u306e\u4e2d\u306b\u306f\u79d1\u5b66\u7684\u30a8\u30d3\u30c7\u30f3\u30b9\u304c\u5c11\u306a\u3044\u3082\u306e\u3082\u5b58\u5728\u3057\u307e\u3059\u3002\u4f8b\u3048\u3070\u30b3\u30e9\u30fc\u30b2\u30f3\u3084\u30d7\u30e9\u30bb\u30f3\u30bf\u30a8\u30ad\u30b9\u914d\u5408\u3092\u8b33\u3046\u88fd\u54c1\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u305d\u308c\u3089\u304c\u7d4c\u76ae\u5438\u53ce\u3055\u308c\u771f\u76ae\u306b\u4f5c\u7528\u3059\u308b\u660e\u78ba\u306a\u6839\u62e0\u306f\u4e4f\u3057\u304f\u3001\u5927\u5206\u5b50\u6210\u5206\u306f\u8868\u9762\u3067\u4fdd\u6e7f\u3059\u308b\u306b\u7559\u307e\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u305f\u3060\u3001\u30bb\u30e9\u30df\u30c9\u3084\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9\u306a\u3069\u306f\u76ae\u819a\u79d1\u5b66\u9818\u57df\u3067\u691c\u8a3c\u304c\u9032\u307f\u3001\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9\u306f\u76ae\u8102\u6291\u5236\u3084\u30d0\u30ea\u30a2\u6a5f\u80fd\u6539\u5584\u306b\u3088\u308b\u6297\u708e\u75c7\u52b9\u679c\u3082\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=Active%20ingredients%20for%20acne%20in,BPO%2C%20benzoyl%20peroxide%3B%20EGCG%2C%20epigallocatechin%E2%80%903%E2%80%90gallate\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=Alpha%E2%80%90hydroxy%20acid%2C%20linoleic%20acid%2C%20salix,BPO%2C%20benzoyl%20peroxide%3B%20EGCG%2C%20epigallocatechin%E2%80%903%E2%80%90gallate\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002<\/p>\n\n\n\n<p><strong>\u6d17\u6d44\u5264:<\/strong> 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AHA\u3084BHA\u3092\u7528\u3044\u305f\u5316\u7ca7\u54c1\u7684\u30d4\u30fc\u30ea\u30f3\u30b0\u306f\u3001\u81e8\u5e8a\u3067\u306f<strong>\u88dc\u52a9\u7684\u6cbb\u7642<\/strong>\u3068\u3057\u3066\u5f79\u7acb\u3063\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u9762\u76b0\u4e3b\u4f53\u306e\u8efd\u75c7\u5c0b\u5e38\u6027\u3056\u7621\u60a3\u8005\u3067\u306f\u3001\u5e02\u8ca9\u306e\u30b5\u30ea\u30c1\u30eb\u9178\u914d\u5408\u30c8\u30ca\u30fc\u3084\u30b0\u30ea\u30b3\u30fc\u30eb\u9178\u914d\u5408\u30ed\u30fc\u30b7\u30e7\u30f3\u306e\u307f\u3067\u75c5\u5909\u6570\u306e\u6e1b\u5c11\u304c\u5831\u544a\u3055\u308c\u3066\u304a\u308a\u3001\u81ea\u5df1\u6cbb\u7642\u306e\u7b2c\u4e00\u6bb5\u968e\u3068\u306a\u308a\u5f97\u307e\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=power%20calculations%20so%20underpowered,it%20is%20not%20possible%20to\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=Those%20evaluating%20dermocosmetic%20monotherapy%20included,it%20is%20difficult%20to%20attribute\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002\u6b27\u7c73\u306e\u7f8e\u5bb9\u76ae\u819a\u79d1\u5b66\u4f1a\u3067\u306f\u3001AHA\/BHA\u542b\u6709\u306e\u300c\u30c0\u30fc\u30de\u30b3\u30b9\u30e1\u30c6\u30a3\u30af\u30b9\u300d\u306f\u533b\u7642\u6cbb\u7642\u3068\u4f75\u7528\u3059\u308b\u3053\u3068\u3067<strong>\u5bdb\u89e3\u7dad\u6301<\/strong>\u3084<strong>\u6cbb\u7642\u52b9\u679c\u5897\u5f37<\/strong>\u306b\u8cc7\u3059\u308b\u3068\u306e\u30b3\u30f3\u30bb\u30f3\u30b5\u30b9\u304c\u3042\u308a\u307e\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=power%20calculations%20so%20underpowered,a%20similar%20process%20to%20the\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=Those%20evaluating%20dermocosmetic%20monotherapy%20included,clinical%20trials%20but%2C%20appreciating%20the\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002\u4e00\u4f8b\u3068\u3057\u3066\u30018%\u30b0\u30ea\u30b3\u30fc\u30eb\u9178\u30ed\u30fc\u30b7\u30e7\u30f3\u3092\u6bdb\u5b54\u6027\u82d4\u766c\u60a3\u8005\u306b12\u9031\u9593\u4f7f\u7528\u3055\u305b\u305f\u8a66\u9a13\u3067\u3001\u6709\u610f\u306a\u4e18\u75b9\u6e1b\u5c11\u3068\u60a3\u8005\u6e80\u8db3\u5ea6\u5411\u4e0a\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u4e2d\u7b49\u5ea6\u306e\u809d\u6591\u6cbb\u7642\u3067\u306f\u3001\u30c8\u30ec\u30c1\u30ce\u30a4\u30f3\u3084\u30cf\u30a4\u30c9\u30ed\u30ad\u30ce\u30f3\u5916\u7528\u306b\u52a0\u3048\u5bb6\u5ead\u3067\u306e\u4f4e\u6fc3\u5ea6\u30d4\u30fc\u30ea\u30f3\u30b0\u77f3\u9e78\u4f7f\u7528\u304c\u8272\u7d20\u6c88\u7740\u6539\u5584\u30b9\u30b3\u30a2\u306e\u5411\u4e0a\u306b\u5bc4\u4e0e\u3057\u305f\u5831\u544a\u3082\u3042\u308a\u307e\u3059\u3002\u4ee5\u4e0a\u3088\u308a\u89d2\u8cea\u30b1\u30a2\u88fd\u54c1\u306f\u3001<strong>\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u5f37\u3055\u3053\u305d\u4e2d\u7a0b\u5ea6<\/strong>\u3067\u3059\u304c\u3001\u9069\u5207\u306b\u7528\u3044\u308c\u3070\u81e8\u5e8a\u4e0a\u6709\u7528\u306a\u88dc\u52a9\u624b\u6bb5\u3068\u306a\u308a\u307e\u3059\u3002\u305f\u3060\u3057\u5f37\u529b\u306a\u52b9\u679c\u3092\u904e\u5ea6\u306b\u671f\u5f85\u3059\u3079\u304d\u3067\u306a\u304f\u3001\u533b\u7642\u4ecb\u5165\u304c\u5fc5\u8981\u306a\u5834\u5408\u306f\u5c02\u9580\u6cbb\u7642\u3078\u8a98\u5c0e\u3059\u308b\u5224\u65ad\u3082\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p><strong>\u7f8e\u767d\u5264:<\/strong> \u7f8e\u767d\u6709\u52b9\u6210\u5206\u306b\u3064\u3044\u3066\u306f<strong>\u6709\u52b9\u6027\u306b\u5dee\u304c\u3042\u308b<\/strong>\u3082\u306e\u306e\u3001\u4e00\u5b9a\u306e\u81e8\u5e8a\u52b9\u679c\u304c\u8a3c\u660e\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u30cf\u30a4\u30c9\u30ed\u30ad\u30ce\u30f3\u306f\u9577\u5e74\u300c\u30b7\u30df\u53d6\u308a\u306e\u30b4\u30fc\u30eb\u30c9\u30b9\u30bf\u30f3\u30c0\u30fc\u30c9\u300d\u3068\u3055\u308c\u3001\u7c73\u56fd\u76ae\u819a\u79d1\u5b66\u4f1a\u3067\u3082\u809d\u6591\u6cbb\u7642\u306e\u4e00\u7dda\u7d1a\uff084% HQ\u30af\u30ea\u30fc\u30e0\uff09\u3068\u3057\u3066\u63a8\u5968\u3055\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u3057\u304b\u3057\u76ae\u819a\u523a\u6fc0\u3084\u5b89\u5168\u6027\u306e\u554f\u984c\u304b\u3089\u3001\u8fd1\u5e74\u306f<strong>\u4ee3\u66ff\u6210\u5206<\/strong>\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u304c\u84c4\u7a4d\u3057\u3066\u3044\u307e\u3059\u3002\u30a2\u30eb\u30d6\u30c1\u30f3\u306fin vitro\u3067\u306e\u30c1\u30ed\u30b7\u30ca\u30fc\u30bc\u963b\u5bb3\u306f\u30cf\u30a4\u30c9\u30ed\u30ad\u30ce\u30f3\u3088\u308a\u7a4f\u3084\u304b\u3067\u3059\u304c\u3001\u30d2\u30c8\u8a66\u9a13\u3067\u306f12\u9031\u5857\u5e03\u3067\u809d\u6591\u30fb\u8001\u4eba\u6027\u8272\u7d20\u6591\u306e\u6709\u610f\u306a\u6de1\u8272\u5316\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059<a href=\"https:\/\/jcadonline.com\/study-depigmenting-agents-skin-color\/#:~:text=at%20concentrations%20up%20to%207,7\" target=\"_blank\" rel=\"noreferrer noopener\">jcadonline.com<\/a>\u3002\u3042\u308b\u6bd4\u8f03\u7814\u7a76\u3067\u306f<strong>\u30a2\u30eb\u30d6\u30c1\u30f3\u306f4%\u30cf\u30a4\u30c9\u30ed\u30ad\u30ce\u30f3\u306b\u5339\u6575\u3059\u308b\u7f8e\u767d\u52b9\u679c<\/strong>\u3092\u793a\u3057\u3001\u5929\u7136\u7531\u6765\u3067\u5b89\u5168\u6027\u304c\u9ad8\u3044\u70b9\u304b\u3089\u6709\u7528\u3068\u7d50\u8ad6\u3055\u308c\u3066\u3044\u307e\u3059<a href=\"https:\/\/jcadonline.com\/study-depigmenting-agents-skin-color\/#:~:text=Comparative%20Study%20on%20Depigmenting%20Agents,\" target=\"_blank\" rel=\"noreferrer noopener\">jcadonline.com<\/a><a href=\"https:\/\/jcadonline.com\/study-depigmenting-agents-skin-color\/#:~:text=Arbutin%2C%20%28hydroquinone,be%20safe%20in%20cosmetic%20products\" target=\"_blank\" rel=\"noreferrer noopener\">jcadonline.com<\/a>\u3002\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9\u306b\u3064\u3044\u3066\u3082\u30012\uff5e5%\u914d\u5408\u306e\u7f8e\u5bb9\u6db2\u304c8\u9031\u9593\u3067\u30e1\u30e9\u30cb\u30f3\u6307\u6570\u3092\u4f4e\u4e0b\u3055\u305b\u3001\u5225\u306e\u30e9\u30f3\u30c0\u30e0\u5316\u8a66\u9a13\u3067\u306f4%\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9\u304c4%\u30cf\u30a4\u30c9\u30ed\u30ad\u30ce\u30f3\u3068<strong>\u540c\u7b49\u306e\u809d\u6591\u6539\u5584\u52b9\u679c<\/strong>\u3092\u793a\u3057\u305f\u3068\u306e\u5831\u544a\u304c\u3042\u308a\u307e\u3059<a href=\"https:\/\/jcadonline.com\/study-depigmenting-agents-skin-color\/#:~:text=Topical%20niacinamide%20is%20believed%20to,lightening%20effect%20compared%20to%20hydroquinone\" target=\"_blank\" rel=\"noreferrer noopener\">jcadonline.com<\/a>\u3002\u30a2\u30bc\u30e9\u30a4\u30f3\u917820%\u30af\u30ea\u30fc\u30e0\u306f\u708e\u75c7\u5f8c\u8272\u7d20\u6c88\u7740(PIH)\u306b\u6709\u52b9\u3067\u30014%\u30cf\u30a4\u30c9\u30ed\u30ad\u30ce\u30f3\u3068\u6bd4\u8f03\u3057\u305f\u4e2d\u6771\u306e\u975e\u76f2\u691c\u8a66\u9a13\u3067\u306f\u30a2\u30bc\u30ea\u30f3\u9178\u306e\u65b9\u304c\u8efd\u5ea6\u809d\u6591\u3067\u512a\u308c\u308b\u7d50\u679c\u3082\u51fa\u3066\u3044\u307e\u3059<a href=\"https:\/\/jcadonline.com\/study-depigmenting-agents-skin-color\/#:~:text=shown%20to%20be%20safe%20and,12%2C%2013\" target=\"_blank\" rel=\"noreferrer noopener\">jcadonline.com<\/a>\uff08\u3082\u3063\u3068\u3082\u6587\u732e\u9593\u3067\u898b\u89e3\u304c\u5206\u304b\u308c\u7d50\u8ad6\u306f\u4e00\u5b9a\u3057\u307e\u305b\u3093<a href=\"https:\/\/jcadonline.com\/study-depigmenting-agents-skin-color\/#:~:text=hyperpigmentation.%5E%7B10%7D%20In%20addition%2C%20a%20non,12%2C%2013\" target=\"_blank\" rel=\"noreferrer noopener\">jcadonline.com<\/a>\uff09\u3002\u690d\u7269\u30a8\u30ad\u30b9\u3067\u306f\u3001\u7518\u8349\u30a8\u30ad\u30b9\u4e2d\u306e\u30ea\u30b3\u30ea\u30b9\u30d5\u30e9\u30dc\u30ce\u30a4\u30c9\u304c<strong>\u30cf\u30a4\u30c9\u30ed\u30ad\u30ce\u30f3\u4ee5\u4e0a\u306e\u7f8e\u767d\u52b9\u679c<\/strong>\u3092\u793a\u3057\u305f\u4f8b\u3084<a href=\"https:\/\/jcadonline.com\/study-depigmenting-agents-skin-color\/#:~:text=a%20common%20ingredient%20of%20skin,preparations%20may%20cause%20allergic%20contact\" target=\"_blank\" rel=\"noreferrer noopener\">jcadonline.com<\/a>\u3001\u30ec\u30ba\u30d9\u30e9\u30c8\u30ed\u30fc\u30eb\u5916\u7528\u3067\u30e1\u30e9\u30cb\u30f3\u7523\u751f\u95a2\u9023\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u6291\u5236\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u7814\u7a76\u306f\u3044\u305a\u308c\u3082\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u304c\u5927\u304d\u304f\u306f\u306a\u304f\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u8cea\u306f\u9650\u5b9a\u7684\u3067\u3059\u304c\u3001\u8907\u6570\u306e\u6210\u5206\u3067\u6709\u52b9\u6027\u304c\u793a\u5506\u3055\u308c\u308b\u3053\u3068\u3067<strong>\u7dcf\u5408\u7684\u306a\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u84c4\u7a4d<\/strong>\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u65e5\u672c\u3067\u5e83\u304f\u4f7f\u308f\u308c\u308b\u30d3\u30bf\u30df\u30f3C\u8a98\u5c0e\u4f53(MAP\u306a\u3069)\u3082\u300110%\u6fc3\u5ea6\u88fd\u5264\u306e\u81e8\u5e8a\u8a66\u9a13\u3067\u809d\u6591\u30fb\u96c0\u5375\u6591\u306e\u6709\u610f\u306a\u6de1\u8272\u5316\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059<a href=\"https:\/\/jcadonline.com\/study-depigmenting-agents-skin-color\/#:~:text=Topical%20stable%20vitamin%20C%2C%20magnesium,Additionally%2C%20ascorbic%20acid%20has%20been\" target=\"_blank\" rel=\"noreferrer noopener\">jcadonline.com<\/a>\u3002\u4ee5\u4e0a\u3088\u308a\u3001\u7f8e\u767d\u5316\u7ca7\u54c1\u306f\u5373\u52b9\u6027\u3053\u305d\u3042\u308a\u307e\u305b\u3093\u304c\u3001<strong>\u9577\u671f\u7684\u306a\u4f7f\u7528\u3067\u81e8\u5e8a\u7684\u306b\u6709\u7528<\/strong>\u306a\u8272\u8abf\u6539\u5584\u52b9\u679c\u3092\u3082\u305f\u3089\u3057\u5f97\u308b\u3068\u3044\u3048\u307e\u3059\u3002\u4f46\u3057\u91cd\u5ea6\u306e\u8272\u7d20\u6591\u3084\u771f\u76ae\u307e\u3067\u53ca\u3076ADM\uff08\u771f\u76ae\u30e1\u30e9\u30ce\u30b5\u30a4\u30c8\u30fc\u30b7\u30b9\uff09\u306b\u306f\u52b9\u679c\u304c\u9650\u3089\u308c\u3001\u5916\u7528\u3067\u6539\u5584\u3057\u306a\u3044\u5834\u5408\u306f\u30ec\u30fc\u30b6\u30fc\u6cbb\u7642\u7b49\u306e\u691c\u8a0e\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u6700\u8fd1\u306e\u7814\u7a76\u52d5\u5411<\/h3>\n\n\n\n<p><strong>\u30b9\u30ad\u30f3\u30de\u30a4\u30af\u30ed\u30d0\u30a4\u30aa\u30fc\u30e0\u7814\u7a76:<\/strong> \u8fd1\u5e74\u3001\u76ae\u819a\u5e38\u5728\u83cc\u53e2\uff08\u30de\u30a4\u30af\u30ed\u30d0\u30a4\u30aa\u30fc\u30e0\uff09\u304c\u76ae\u819a\u306e\u5065\u5eb7\u306b\u679c\u305f\u3059\u5f79\u5272\u306b\u6ce8\u76ee\u304c\u96c6\u307e\u308a\u3001\u30b9\u30ad\u30f3\u30b1\u30a2\u5316\u7ca7\u54c1\u306b\u3082\u5fdc\u7528\u304c\u59cb\u307e\u3063\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070<strong>\u30d7\u30ed\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\u5916\u7528<\/strong>\u3068\u3057\u3066\u3001\u4e73\u9178\u83cc\u767a\u9175\u7523\u7269\u3084\u30d0\u30af\u30c6\u30ea\u30a2\u6eb6\u89e3\u7523\u7269\u3092\u914d\u5408\u3057\u305f\u4fdd\u6e7f\u5264\u304c\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u60a3\u8005\u306e\u76ae\u819a\u30d0\u30ea\u30a2\u3092\u6539\u5584\u3059\u308b\u53ef\u80fd\u6027\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=Active%20ingredients%20for%20acne%20in,BPO%2C%20benzoyl%20peroxide%3B%20EGCG%2C%20epigallocatechin%E2%80%903%E2%80%90gallate\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002\u30d5\u30e9\u30f3\u30b9\u3067\u306fVitroscilla filiformis\u3068\u3044\u3046\u7d30\u83cc\u57f9\u990a\u6db2\u3092\u542b\u3080\u30b9\u30d7\u30ec\u30fc\u304c\u30a2\u30c8\u30d4\u30fc\u808c\u7528\u306b\u767a\u58f2\u3055\u308c\u3001\u76ae\u819a\u708e\u75c7\u3092\u6291\u3048\u308b\u4f5c\u7528\u304c\u7814\u7a76\u3055\u308c\u3066\u3044\u307e\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=Active%20ingredients%20for%20acne%20in,BPO%2C%20benzoyl%20peroxide%3B%20EGCG%2C%20epigallocatechin%E2%80%903%E2%80%90gallate\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002\u307e\u305f<strong>\u5e38\u5728\u83cc\u306b\u914d\u616e\u3057\u305f\u6d17\u6d44<\/strong>\uff08\u6d17\u3044\u3059\u304e\u306b\u3088\u308b\u83cc\u53e2\u64b9\u4e71\u3092\u9632\u3050\uff09\u306a\u3069\u3001\u30de\u30a4\u30af\u30ed\u30d0\u30a4\u30aa\u30fc\u30e0\u30d5\u30ec\u30f3\u30c9\u30ea\u30fc\u3092\u8b33\u3046\u30b9\u30ad\u30f3\u30b1\u30a2\u958b\u767a\u3082\u30c8\u30ec\u30f3\u30c9\u3067\u3059\u3002<\/p>\n\n\n\n<p><strong>\u30a2\u30f3\u30c1\u30a8\u30a4\u30b8\u30f3\u30b0\u7814\u7a76\u306e\u6df1\u5316:<\/strong> \u5f93\u6765\u306e\u30b3\u30e9\u30fc\u30b2\u30f3\u7523\u751f\u4fc3\u9032\u3084\u6297\u9178\u5316\u306b\u52a0\u3048\u3001\u7d30\u80de\u30ec\u30d9\u30eb\u306e\u8001\u5316\u6a5f\u69cb\u306b\u7740\u76ee\u3057\u305f\u300c<strong>\u9577\u5bff\u547d\u30b3\u30b9\u30e1<\/strong>\u300d\u306e\u6982\u5ff5\u304c\u63d0\u5531\u3055\u308c\u3066\u3044\u307e\u3059<a href=\"https:\/\/www.frontiersin.org\/journals\/aging\/articles\/10.3389\/fragi.2025.1586999\/full#:~:text=The%20field%20of%20anti,the%20first%20time%2C%20longevity%20cosmeceutical\" target=\"_blank\" rel=\"noreferrer noopener\">frontiersin.org<\/a><a href=\"https:\/\/www.frontiersin.org\/journals\/aging\/articles\/10.3389\/fragi.2025.1586999\/full#:~:text=cosmeceutical%20actives%20and%20products,efficacy%20must%20be%20validated%20through\" target=\"_blank\" rel=\"noreferrer noopener\">frontiersin.org<\/a>\u3002\u4f8b\u3048\u3070\u7d30\u80de\u8001\u5316\uff08\u30bb\u30cd\u30bb\u30f3\u30b9\uff09\u3092\u6291\u5236\u3059\u308b\u30bb\u30ce\u30eaytics\u3084\u3001\u7d30\u80de\u306eNAD\u4ee3\u8b1d\u3092\u4fc3\u9032\u3059\u308b\u30cb\u30b3\u30c1\u30f3\u30a2\u30df\u30c9\u30e2\u30ce\u30cc\u30af\u30ec\u30aa\u30c1\u30c9(NMN)\u306a\u3069\u6297\u8001\u5316\u7269\u8cea\u3092\u76ae\u819a\u306b\u5fdc\u7528\u3059\u308b\u8a66\u307f\u304c\u3042\u308a\u307e\u3059\u3002\u307e\u305f\u8001\u5316\u306e\u5206\u5b50\u7684\u6307\u6a19\u3067\u3042\u308b\u300c\u8001\u5316\u306e12\u306e\u30db\u30fc\u30eb\u30de\u30fc\u30af\u300d\u306b\u4f5c\u7528\u3059\u308b\u3088\u3046\u8a2d\u8a08\u3055\u308c\u305f\u6210\u5206\u7fa4\uff08\u4f8b: \u30b5\u30fc\u30c1\u30e5\u30a4\u30f3\u6d3b\u6027\u5316\u7269\u8cea\u3068\u3057\u3066\u306e\u30ec\u30b9\u30d9\u30e9\u30c8\u30ed\u30fc\u30eb\u3084\u3001\u8001\u5316\u8272\u7d20\u30ea\u30dd\u30d5\u30b9\u30c1\u30f3\u9664\u53bb\u3092\u76ee\u6307\u3059\u5206\u5b50\uff09\u304c\u7814\u7a76\u3055\u308c\u3066\u3044\u307e\u3059<a href=\"https:\/\/www.frontiersin.org\/journals\/aging\/articles\/10.3389\/fragi.2025.1586999\/full#:~:text=marketing,applications%2C%20and%20recommends%20essential%20biomarkers\" target=\"_blank\" rel=\"noreferrer noopener\">frontiersin.org<\/a><a href=\"https:\/\/www.frontiersin.org\/journals\/aging\/articles\/10.3389\/fragi.2025.1586999\/full#:~:text=and%20modulate%20established%20hallmarks%20of,emphasize%20the%20importance%20of%20robust\" target=\"_blank\" rel=\"noreferrer noopener\">frontiersin.org<\/a>\u30022025\u5e74\u306e\u5831\u544a\u3067\u306f\u3001\u3053\u308c\u3089**\u30b8\u30a7\u30ed\u30d7\u30ed\u30c6\u30af\u30bf\u30fc(\u8001\u5316\u9632\u5fa1\u7269\u8cea)**\u3092\u7d44\u307f\u8fbc\u3093\u3060\u5316\u7ca7\u54c1\u3092\u300c\u9577\u5bff\u30b3\u30b9\u30e1\uff08longevity cosmeceuticals\uff09\u300d\u3068\u5b9a\u7fa9\u3057\u3001\u5358\u306a\u308b\u30b7\u30ef\u6539\u5584\u306b\u7559\u307e\u3089\u305a\u76ae\u819a\u306e\u751f\u7269\u5b66\u7684\u8001\u5316\u6307\u6a19\u306b\u50cd\u304d\u304b\u3051\u308b\u30a2\u30d7\u30ed\u30fc\u30c1\u304c\u63d0\u6848\u3055\u308c\u307e\u3057\u305f<a href=\"https:\/\/www.frontiersin.org\/journals\/aging\/articles\/10.3389\/fragi.2025.1586999\/full#:~:text=The%20field%20of%20anti,the%20first%20time%2C%20longevity%20cosmeceutical\" target=\"_blank\" rel=\"noreferrer noopener\">frontiersin.org<\/a><a href=\"https:\/\/www.frontiersin.org\/journals\/aging\/articles\/10.3389\/fragi.2025.1586999\/full#:~:text=cosmeceutical%20actives%20and%20products,skin%20biopsies%20to%20evaluate%20aging\" target=\"_blank\" rel=\"noreferrer noopener\">frontiersin.org<\/a>\u3002\u4f8b\u3048\u3070\u3001\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u306e\u30d5\u30e9\u30d0\u30f33\u30aa\u30fc\u30eb\u304c\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a5f\u80fd\u3092\u9ad8\u3081\u7d30\u80de\u8001\u5316\u3092\u9045\u5ef6\u3055\u305b\u308b\u53ef\u80fd\u6027\u306a\u3069\u304c\u8a66\u9a13\u7ba1\u30ec\u30d9\u30eb\u3067\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3082\u3063\u3068\u3082\u30d2\u30c8\u3067\u306e\u5b9f\u8a3c\u306f\u3053\u308c\u304b\u3089\u3067\u3042\u308a\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u78ba\u7acb\u306b\u306f\u6642\u9593\u3092\u8981\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u305d\u306e\u4ed6\u306e\u65b0\u5c55\u958b:<\/strong> 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+ \u5de5\u5b66 + \u6b21\u4e16\u4ee3\u6280\u8853\u300d\u306e\u878d\u5408\u3078\u5411\u304b\u3063\u3066\u304a\u308a\u3001\u7f8e\u5bb9\u76ae\u819a\u79d1\u306e\u5b9f\u8df5\u306b\u3082\u9806\u6b21\u53cd\u6620\u3055\u308c\u3066\u3044\u304f\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. \u6a5f\u80fd\u6027\u5316\u7ca7\u54c1\uff08\u30a2\u30f3\u30c1\u30a8\u30a4\u30b8\u30f3\u30b0\u30fb\u30cb\u30ad\u30d3\u30fb\u3057\u307f\u30fb\u30b7\u30ef\u30fb\u30cf\u30ea\u5bfe\u7b56\u306a\u3069\uff09<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">\u4e3b\u8981\u6210\u5206\u3068\u4f5c\u7528\u6a5f\u5e8f<\/h3>\n\n\n\n<p><strong>\u30a2\u30f3\u30c1\u30a8\u30a4\u30b8\u30f3\u30b0\u6210\u5206:<\/strong> <strong>\u30ec\u30c1\u30ce\u30fc\u30eb<\/strong>\uff08\u30d3\u30bf\u30df\u30f3A\u8a98\u5c0e\u4f53\uff09\u306f\u6700\u3082\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u3042\u308b\u6297\u8001\u5316\u6210\u5206\u3067\u3001\u8868\u76ae\u306e\u30bf\u30fc\u30f3\u30aa\u30fc\u30d0\u30fc\u4fc3\u9032\u3068\u771f\u76ae\u3067\u306e\u30b3\u30e9\u30fc\u30b2\u30f3\u65b0\u751f\u4fc3\u9032\u306b\u3088\u308a\u30b7\u30ef\u6539\u5584\u306b\u5bc4\u4e0e\u3057\u307e\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11268769\/#:~:text=applications%20of%20AHAs%2C%20particularly%20in,Regulatory%20compliance%20is\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11268769\/#:~:text=analysis%20reveals%20a%20nuanced%20understanding,dermatology%2C%20emphasizing%20the%20necessity%20for\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002\u30ec\u30c1\u30ce\u30fc\u30eb\u306f\u76ae\u819a\u5185\u3067\u30ec\u30c1\u30ca\u30fc\u30eb\u3084\u30ec\u30c1\u30ce\u30a4\u30f3\u9178\u306b\u5909\u63db\u3055\u308c\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u5206\u89e3\u9175\u7d20(MMP)\u7523\u751f\u3092\u6291\u5236\u3057\u3064\u3064I\u578b\u30b3\u30e9\u30fc\u30b2\u30f3\u7523\u751f\u3092\u5897\u52a0\u3055\u305b\u308b\u3053\u3068\u3067\u3001\u30b7\u30ef\u3084\u305f\u308b\u307f\u3092\u6539\u5584\u3057\u307e\u3059\u3002\u307e\u305f\u8868\u76ae\u306e\u30e1\u30e9\u30cb\u30f3\u6392\u51fa\u3082\u4fc3\u3059\u305f\u3081\u8272\u30e0\u30e9\u6539\u5584\u306b\u3082\u6709\u52b9\u3067\u3059\u3002<strong>\u30d3\u30bf\u30df\u30f3C\uff08\u30a2\u30b9\u30b3\u30eb\u30d3\u30f3\u9178\uff09\u3082\u6297\u9178\u5316\u4f5c\u7528\u3067\u6d3b\u6027\u9178\u7d20\u306b\u3088\u308b\u30b3\u30e9\u30fc\u30b2\u30f3\u5206\u89e3\u3092\u6291\u5236\u3057\u3001\u3055\u3089\u306b\u30b3\u30e9\u30fc\u30b2\u30f3\u5408\u6210\u306e\u88dc\u56e0\u5b50\u3068\u3057\u3066\u5b89\u5b9a\u306a\u30b3\u30e9\u30fc\u30b2\u30f3\u7db2\u5f62\u6210\u3092\u52a9\u3051\u307e\u3059\u3002\u30d3\u30bf\u30df\u30f3C\u8a98\u5c0e\u4f53\uff08\u30ea\u30f3\u9178\u578b\u306a\u3069\uff09\u306f\u5b89\u5b9a\u6027\u30fb\u6d78\u900f\u6027\u3092\u9ad8\u3081\u305f\u5f62\u3067\u914d\u5408\u3055\u308c\u3001\u5149\u8001\u5316\u306b\u3088\u308b\u3057\u307f\u30fb\u3057\u308f\u53cc\u65b9\u306b\u52b9\u679c\u3092\u767a\u63ee\u3057\u307e\u3059<a href=\"https:\/\/jcadonline.com\/study-depigmenting-agents-skin-color\/#:~:text=Topical%20stable%20vitamin%20C%2C%20magnesium,Additionally%2C%20ascorbic%20acid%20has%20been\" target=\"_blank\" rel=\"noreferrer noopener\">jcadonline.com<\/a>\u3002\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9\uff08\u30d3\u30bf\u30df\u30f3B3\uff09\u306f\u8fd1\u5e74\u6ce8\u76ee\u306e\u591a\u6a5f\u80fd\u6210\u5206\u3067\u3001\u30b1\u30e9\u30c1\u30ce\u30b5\u30a4\u30c8\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\u3092\u9ad8\u3081\u30d0\u30ea\u30a2\u6a5f\u80fd\u3068\u4fdd\u6e7f\u529b\u3092\u6539\u5584\u3059\u308b\u307b\u304b\u3001\u6297\u708e\u75c7\u4f5c\u7528\u3067\u9ec4\u3050\u3059\u307f\u3084\u8d64\u3089\u9854\u3092\u8efd\u6e1b\u3059\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3055\u3089\u306b\u30e1\u30e9\u30ce\u30bd\u30fc\u30e0\u8ee2\u9001\u6291\u5236\u306b\u3088\u308b\u7f8e\u767d\u3084\u76ae\u8102\u5206\u6ccc\u6291\u5236\u306b\u3088\u308b\u6297\u30cb\u30ad\u30d3\u4f5c\u7528\u3082\u6301\u3061\u3001\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u5168\u822c\u306b\u6709\u7528\u3067\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=As%20an%20initial%20step%20based,with%20the%20categorization%20of%20quality\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=dermocosmetics%2C%20cosmeceutical%2C%20salicylic%20acid%2C%20lipohydroxyacid%2C,The%20search%20results%20were%20then\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002\u30da\u30d7\u30c1\u30c9\u6210\u5206\uff08\u30a2\u30eb\u30b8\u30eb\u30ea\u30f3\u306a\u3069\u306e\u30b7\u30b0\u30ca\u30eb\u30da\u30d7\u30c1\u30c9\uff09\u306f\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u3084\u30a8\u30e9\u30b9\u30c1\u30f3\u7523\u751f\u3092\u4fc3\u3059\u7d30\u80de\u30b7\u30b0\u30ca\u30eb\u3092\u6a21\u5023\u3057\u3001\u808c\u306e\u30cf\u30ea\u3092\u9ad8\u3081\u308b\u3068\u3055\u308c\u307e\u3059\u3002\u4f8b\u3048\u3070\u30d1\u30eb\u30df\u30c8\u30a4\u30eb\u30da\u30f3\u30bf\u30da\u30d7\u30c1\u30c9-4\uff08\u30de\u30c8\u30ea\u30ad\u30b7\u30eb\uff09\u306f\u771f\u76ae\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u6210\u5206\u7523\u751f\u3092\u4ea2\u9032\u3057\u3001\u5c0f\u30b8\u30ef\u306e\u7d71\u8a08\u5b66\u7684\u6539\u5584\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u6210\u9577\u56e0\u5b50(EGF\u7b49)\u3092\u914d\u5408\u3057\u305f\u30b3\u30b9\u30e1\u3082\u4e00\u90e8\u306b\u3042\u308a\u307e\u3059\u304c\u3001\u6d78\u900f\u3084\u4f5c\u7528\u6a5f\u5e8f\u306b\u306f\u4e0d\u660e\u70b9\u3082\u591a\u304f\u8cdb\u5426\u304c\u3042\u308a\u307e\u3059\u3002\u6297\u9178\u5316\u690d\u7269\u30a8\u30ad\u30b9\uff08\u7dd1\u8336\u30ab\u30c6\u30ad\u30f3\u3001\u30ec\u30b9\u30d9\u30e9\u30c8\u30ed\u30fc\u30eb\u7b49\uff09\u3082\u30d5\u30ea\u30fc\u30e9\u30b8\u30ab\u30eb\u6d88\u53bb\u306b\u3088\u308a\u5149\u8001\u5316\u3092\u6291\u3048\u308b\u76ee\u7684\u3067\u914d\u5408\u3055\u308c\u307e\u3059\u3002\u30ec\u30b9\u30d9\u30e9\u30c8\u30ed\u30fc\u30eb\u306f\u30b5\u30fc\u30c1\u30e5\u30a4\u30f3\u907a\u4f1d\u5b50\u6d3b\u6027\u5316\u3092\u4ecb\u3057\u305f\u7d30\u80de\u8001\u5316\u6291\u5236\u4f5c\u7528\u3082\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3055\u3089\u306b\u8fd1\u5e74\u306fDNA\u4fee\u5fa9\u9175\u7d20\uff08\u30ea\u30bd\u30bd\u30fc\u30e0T4\u30a8\u30f3\u30c9\u30cc\u30af\u30ec\u30a2\u30fc\u30bc\u306a\u3069\uff09\u3092\u30ea\u30dd\u30bd\u30fc\u30e0\u5316\u3057\u3066\u914d\u5408\u3057\u3001\u7d2b\u5916\u7dda\u3067\u50b7\u3064\u3044\u305fDNA\u4fee\u5fa9\u3092\u52a9\u3051\u308b\u30b3\u30f3\u30bb\u30d7\u30c8\u306e\u5546\u54c1\u3082\u767b\u5834\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u591a\u69d8\u306a\u6210\u5206\u304c\u76f8\u4e57\u52b9\u679c<\/strong>\u3092\u72d9\u3063\u3066\u7d44\u307f\u5408\u308f\u3055\u308c\u3001\u30b7\u30ef\u30fb\u305f\u308b\u307f\u30fb\u304f\u3059\u307f\u30fb\u4e7e\u71e5\u306a\u3069\u8001\u5316\u5fb4\u5019\u306b\u5305\u62ec\u7684\u306b\u30a2\u30d7\u30ed\u30fc\u30c1\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u30cb\u30ad\u30d3\u5bfe\u7b56\u6210\u5206:<\/strong> \u6a5f\u80fd\u6027\u5316\u7ca7\u54c1\u306e\u4e2d\u3067\u3082<strong>\u6297\u30cb\u30ad\u30d3<\/strong>\u3092\u76ee\u7684\u3068\u3057\u305f\u3082\u306e\u306f\u3001\u300c\u30b3\u30e1\u30c9\u5f62\u6210\u6291\u5236\u300d\u300c\u6297\u83cc\u30fb\u6297\u708e\u75c7\u300d\u300c\u76ae\u8102\u6291\u5236\u300d\u306e\u6210\u5206\u3092\u542b\u307f\u307e\u3059\u3002\u4e3b\u306a\u3082\u306e\u306f<strong>\u30b5\u30ea\u30c1\u30eb\u9178<\/strong>\u3084<strong>\u30ea\u30dd\u30d2\u30c9\u30ed\u30ad\u30b7\u9178(LHA)<\/strong>\uff08\u30b5\u30ea\u30c1\u30eb\u9178\u8a98\u5c0e\u4f53\uff09\u3067\u3001\u89d2\u8cea\u5265\u96e2\u3068\u6bdb\u7a74\u8a70\u307e\u308a\u89e3\u6d88\u306b\u3088\u308a\u9762\u76b0\u306e\u751f\u6210\u3092\u6291\u5236\u3057\u307e\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=Active%20ingredients%20for%20acne%20in,BPO%2C%20benzoyl%20peroxide%3B%20EGCG%2C%20epigallocatechin%E2%80%903%E2%80%90gallate\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=Alpha%E2%80%90hydroxy%20acid%2C%20linoleic%20acid%2C%20salix,BPO%2C%20benzoyl%20peroxide%3B%20EGCG%2C%20epigallocatechin%E2%80%903%E2%80%90gallate\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002**\u904e\u9178\u5316\u30d9\u30f3\u30be\u30a4\u30eb(BPO)**\u306f\u672c\u6765\u533b\u85ac\u54c1\u6210\u5206\u3067\u3059\u304c\u3001\u4f4e\u6fc3\u5ea6\uff082.5%\u4ee5\u4e0b\uff09\u3067\u914d\u5408\u3057\u305f\u88fd\u54c1\u304c\u6d77\u5916\u3067\u306fOTC\u5c55\u958b\u3055\u308c\u3001\u6bdb\u5305\u5185\u306e\u30a2\u30af\u30cd\u83cc\u3092\u6bba\u83cc\u3057\u708e\u75c7\u6027\u75c5\u5909\u3092\u6e1b\u3089\u3057\u307e\u3059\uff08\u65e5\u672c\u3067\u306f\u533b\u85ac\u54c1\u6271\u3044\uff09\u3002<strong>\u30ec\u30c1\u30ce\u30fc\u30eb<\/strong>\u3082\u30bf\u30fc\u30f3\u30aa\u30fc\u30d0\u30fc\u4fc3\u9032\u3067\u8efd\u3044\u30cb\u30ad\u30d3\u306b\u6709\u52b9\u3067\u3059\u3002<strong>\u30cb\u30b3\u30c1\u30f3\u30a2\u30df\u30c9\uff08\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9\uff09\u306f\u6297\u708e\u75c7\u4f5c\u7528\u3068\u76ae\u8102\u7523\u751f\u4f4e\u4e0b\u4f5c\u7528\u306b\u3088\u308a\u3001\u8d64\u307f\u3092\u5e2f\u3073\u305f\u708e\u75c7\u6027\u4e18\u75b9\u306e\u93ae\u9759\u3084\u8102\u6027\u808c\u306e\u30c6\u30ab\u30ea\u8efd\u6e1b\u306b\u5f79\u7acb\u3061\u307e\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=As%20an%20initial%20step%20based,with%20the%20categorization%20of%20quality\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=dermocosmetics%2C%20cosmeceutical%2C%20salicylic%20acid%2C%20lipohydroxyacid%2C,with%20the%20categorization%20of%20quality\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002\u6297\u83cc\u6210\u5206\u3068\u3057\u3066\u306f\u30a4\u30aa\u30a6\uff08\u89d2\u8cea\u6eb6\u89e3\u30fb\u9759\u83cc\u4f5c\u7528\uff09\u3001\u30ec\u30be\u30eb\u30b7\u30ce\u30fc\u30eb\u3001\u30c8\u30ea\u30af\u30ed\u30b5\u30f3\uff08\u73fe\u5728\u306f\u4f7f\u7528\u6e1b\uff09\u306a\u3069\u304c\u6319\u3052\u3089\u308c\u307e\u3059\u3002\u5929\u7136\u7531\u6765\u3067\u306f\u30c6\u30a3\u30fc\u30c4\u30ea\u30fc\u30aa\u30a4\u30eb<\/strong>\uff08\u30c6\u30eb\u30d4\u30cd\u30f3-4-\u30aa\u30fc\u30eb\u3092\u4e3b\u6210\u5206\uff09\u304c\u6297\u83cc\u30fb\u6297\u708e\u75c7\u52b9\u679c\u3067\u6ce8\u76ee\u3055\u308c\u3001\u5e02\u8ca9\u306e\u30cb\u30ad\u30d3\u7528\u30b9\u30dd\u30c3\u30c4\u88fd\u54c1\u306b\u914d\u5408\u3055\u308c\u3066\u3044\u307e\u3059\u300210%\u30c6\u30a3\u30fc\u30c4\u30ea\u30fc\u30aa\u30a4\u30eb\u30b2\u30eb\u306f5%\u30d9\u30f3\u30be\u30a4\u30eb\u904e\u9178\u5316\u7269\u3068\u540c\u7b49\u306e\u8efd\u5ea6\u30cb\u30ad\u30d3\u6539\u5584\u52b9\u679c\u3092\u793a\u3057\u305f\u8a66\u9a13\u3082\u3042\u308a\u307e\u3059\u3002<strong>\u4e9c\u925b\u5316\u5408\u7269<\/strong>\uff08\u30d4\u30ea\u30c1\u30aa\u30f3\u4e9c\u925b\u3084\u30b0\u30eb\u30b3\u30f3\u9178\u4e9c\u925b\uff09\u306f\u76ae\u8102\u817a\u3078\u306e\u6297\u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\u4f5c\u7528\u3084\u6297\u83cc\u4f5c\u7528\u304c\u3042\u308a\u3001\u5916\u7528\u3067\u708e\u75c7\u3092\u6291\u3048\u308b\u88dc\u52a9\u306b\u306a\u308a\u307e\u3059\u3002\u5b9f\u969b\u3001\u4e9c\u925b\u3092\u542b\u3080\u5316\u7ca7\u6c34\u3067\u76ae\u8102\u5206\u6ccc\u3084\u6bdb\u7a74\u76ee\u7acb\u3061\u3092\u6291\u3048\u308b\u52b9\u679c\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u3002<strong>AHA\uff08\u30b0\u30ea\u30b3\u30fc\u30eb\u9178\uff09\u3082\u30cb\u30ad\u30d3\u808c\u306b\u7528\u3044\u3089\u308c\u3001\u7a4f\u3084\u304b\u306a\u30d4\u30fc\u30ea\u30f3\u30b0\u4f5c\u7528\u3067\u89d2\u8cea\u80a5\u539a\u3068\u8272\u7d20\u6c88\u7740\u3092\u6539\u5584\u3057\u307e\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11268769\/#:~:text=enabling%20effective%20skin%20penetration,10%20%2C%2033\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002\u3055\u3089\u306b\u30d7\u30ed\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\u5916\u7528<\/strong>\uff08\u4e73\u9178\u83cc\u7531\u6765\u6210\u5206\uff09\u3067\u808c\u8868\u9762\u306e\u5fae\u751f\u7269\u30d0\u30e9\u30f3\u30b9\u3092\u6574\u3048\u3001\u30cb\u30ad\u30d3\u83cc\u306e\u904e\u5270\u7e41\u6b96\u3092\u9632\u3050\u8a66\u307f\u3082\u3042\u308a\u307e\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=Active%20ingredients%20for%20acne%20in,BPO%2C%20benzoyl%20peroxide%3B%20EGCG%2C%20epigallocatechin%E2%80%903%E2%80%90gallate\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002\u88fd\u54c1\u3068\u3057\u3066\u306f\u6297\u30cb\u30ad\u30d3\u6210\u5206\u3092\u8907\u6570\u7d44\u307f\u5408\u308f\u305b\u305f\u300c<strong>\u30a2\u30af\u30cd\u30b1\u30a2\u30e9\u30a4\u30f3<\/strong>\u300d\u304c\u4e00\u822c\u7684\u3067\u3001\u6d17\u9854\u2192\u5316\u7ca7\u6c34\u2192\u7f8e\u5bb9\u6db2\u3068\u4e00\u9023\u306e\u51e6\u65b9\u3067\u4f5c\u7528\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u3057\u307f\u30fb\u304f\u3059\u307f\u5bfe\u7b56:<\/strong> \u7f8e\u767d\u6210\u5206\u306f\u524d\u7bc0\u30b9\u30ad\u30f3\u30b1\u30a2\u5316\u7ca7\u54c1\u3068\u91cd\u8907\u3057\u307e\u3059\u304c\u3001\u6a5f\u80fd\u6027\u5316\u7ca7\u54c1\u3068\u3057\u3066<strong>\u9ad8\u6fc3\u5ea6\u7f8e\u5bb9\u6db2<\/strong>\u306a\u3069\u306b\u914d\u5408\u3055\u308c\u308b\u30b1\u30fc\u30b9\u304c\u591a\u3044\u3067\u3059\u3002\u30cf\u30a4\u30c9\u30ed\u30ad\u30ce\u30f3\u306f\u533b\u7642\u6a5f\u95a2\u5411\u3051\u5916\u7528\u5264\uff08\u30af\u30ea\u30cb\u30c3\u30af\u5c02\u58f2\u30b3\u30b9\u30e1\u306a\u3069\uff09\u30674%\u4ee5\u4e0b\u306e\u6fc3\u5ea6\u914d\u5408\u88fd\u54c1\u304c\u3042\u308a\u307e\u3059\u3002<strong>\u30c8\u30e9\u30cd\u30ad\u30b5\u30e0\u9178<\/strong>\u3082\u65e5\u672c\u3067\u809d\u6591\u6cbb\u7642\u306e\u5185\u670d\u85ac\u3068\u3057\u3066\u6709\u540d\u3067\u3059\u304c\u3001\u5916\u7528\u3067\u3082\u30e1\u30e9\u30ce\u30b5\u30a4\u30c8\u306e\u6d3b\u6027\u5316\u7d4c\u8def\uff08\u30d7\u30e9\u30b9\u30df\u30f3\u7d4c\u8def\uff09\u3092\u6291\u3048\u308b\u4f5c\u7528\u304c\u3042\u308a\u3001\u7f8e\u767d\u6709\u52b9\u6210\u5206\u3068\u3057\u3066\u533b\u85ac\u90e8\u5916\u54c1\u306b\u627f\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u30ab\u30e2\u30df\u30e9ET\uff08\u30ab\u30e2\u30df\u30fc\u30eb\u7531\u6765\u30a8\u30ad\u30b9\uff09\u3082\u6297\u708e\u75c7\u4f5c\u7528\u3067\u708e\u75c7\u6027\u306e\u30b7\u30df\u4e88\u9632\u52b9\u679c\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<strong>\u30a2\u30eb\u30d6\u30c1\u30f3\u3001\u30d3\u30bf\u30df\u30f3C\u8a98\u5c0e\u4f53\u3001\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9<\/strong>\u306f\u3057\u307f\u30fb\u304f\u3059\u307f\u5bfe\u7b56\u306e\u5b9a\u756a\u3067\u3001<strong>\u8907\u6570\u6210\u5206\u3092\u7d44\u307f\u5408\u308f\u305b\u305f\u7f8e\u767d\u7f8e\u5bb9\u6db2<\/strong>\u304c\u591a\u304f\u5e02\u8ca9\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u30a2\u30eb\u30d6\u30c1\u30f3\u3068\u30d3\u30bf\u30df\u30f3C\u8a98\u5c0e\u4f53\u306b\u52a0\u3048\u3001\u4fdd\u6e7f\u3084\u6297\u708e\u75c7\u6210\u5206\u3092\u5165\u308c\u3066\u523a\u6fc0\u3092\u6291\u3048\u3064\u3064\u52b9\u679c\u3092\u5e95\u4e0a\u3052\u3059\u308b\u51e6\u65b9\u3067\u3059\u3002\u8fd1\u5e74\u65b0\u3057\u3044\u30a2\u30d7\u30ed\u30fc\u30c1\u3068\u3057\u3066<strong>Cyspera (\u30b7\u30b9\u30da\u30e9)\u3068\u3044\u3046\u30b7\u30b9\u30c6\u30a2\u30df\u30f3\u914d\u5408\u30af\u30ea\u30fc\u30e0\u304c\u6d77\u5916\u3067\u811a\u5149\u3092\u6d74\u3073\u3066\u3044\u307e\u3059\u3002\u30b7\u30b9\u30c6\u30a2\u30df\u30f3\u306f\u30e1\u30e9\u30cb\u30f3\u751f\u5408\u6210\u7d4c\u8def\u306e\u69d8\u3005\u306a\u6bb5\u968e\u3092\u963b\u5bb3\u3057\u3001\u81e8\u5e8a\u8a66\u9a13\u3067\u809d\u6591\u306e\u9855\u8457\u306a\u6539\u5584\u304c\u5831\u544a\u3055\u308c\u307e\u3057\u305f\u3002\u305f\u3060\u81ed\u6c17\u304c\u5f37\u304f\u4e00\u6642\u7684\u523a\u6fc0\u3082\u3042\u308b\u305f\u3081\u3001\u65e5\u672c\u3067\u306f\u307e\u3060\u4e00\u822c\u5316\u3057\u3066\u3044\u307e\u305b\u3093\u3002\u4ed6\u306b\u306f\u30ea\u30b3\u30d4\u30f3\uff08\u30c8\u30de\u30c8\u8272\u7d20\u306e\u6297\u9178\u5316\u5264\uff09\u3084\u30a8\u30e9\u30b0\u9178\uff08\u30b6\u30af\u30ed\u7531\u6765\uff09\u306a\u3069\u3001\u591a\u5f69\u306a\u7d20\u6750\u304c\u30d6\u30e9\u30a4\u30c8\u30cb\u30f3\u30b0\uff08\u808c\u306e\u8f1d\u304d\u5411\u4e0a\uff09\u76ee\u7684\u3067\u63a1\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u3057\u307f\u30fb\u7f8e\u767d\u5bfe\u7b56\u6210\u5206\u306f\u3001\u901a\u5e38\u306f\u9577\u671f\u4f7f\u7528\u3067\u7a4f\u3084\u304b\u306b\u52b9\u679c<\/strong>\u304c\u73fe\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u30b7\u30ef\u30fb\u30cf\u30ea\u5bfe\u7b56:<\/strong> 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class=\"wp-block-heading\">\u9069\u5fdc\u3068\u4f7f\u7528\u6cd5<\/h3>\n\n\n\n<p><strong>\u30a2\u30f3\u30c1\u30a8\u30a4\u30b8\u30f3\u30b0\u7528\u9014:<\/strong> 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\u6a5f\u80fd\u6027\u5316\u7ca7\u54c1\u306f<strong>\u8efd\u75c7\u306e\u5c0b\u5e38\u6027\u3056\u7621<\/strong>\u3084\u6cbb\u7642\u5f8c\u306e\u7dad\u6301\u7642\u6cd5\u3068\u3057\u3066\u9069\u5fdc\u3057\u307e\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=A%20live%20meeting%20of%20the,from%20Argentina%2C%20Brazil%2C%20China%2C%20France\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=maintenance%20post%20medical%20treatment%20and,from%20Argentina%2C%20Brazil%2C%20China%2C%20France\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002\u9762\u76b0\u304c\u4e2d\u5fc3\u3067\u708e\u75c7\u306e\u4e4f\u3057\u3044\u521d\u671f\u30cb\u30ad\u30d3\u306b\u306f\u3001\u5e02\u8ca9\u306e\u30b5\u30ea\u30c1\u30eb\u9178\u5165\u308a\u6d17\u9854\u3084\u30cb\u30ad\u30d3\u7528\u5316\u7ca7\u6c34\u3067\u5341\u5206\u5bfe\u51e6\u53ef\u80fd\u306a\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002\u5b9f\u969b\u3001\u56fd\u969b\u7684\u306a\u5c02\u9580\u5bb6\u30b3\u30f3\u30bb\u30f3\u30b5\u30b9\u3067\u3082\u300c\u51e6\u65b9\u85ac\u3092\u4f7f\u308f\u306a\u3044\u8efd\u75c7\u30cb\u30ad\u30d3\u60a3\u8005\u306e\u7b2c\u4e00\u9078\u629e\u3068\u3057\u3066\u9069\u5207\u306a\u30b9\u30ad\u30f3\u30b1\u30a2\u88fd\u54c1\u3092\u52e7\u3081\u308b\u300d\u3053\u3068\u304c\u63a8\u5968\u3055\u308c\u3066\u3044\u307e\u3059<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38877766\/#:~:text=Background%3A%20%20A%20wide%20variety,targeting%20ingredients\" target=\"_blank\" rel=\"noreferrer noopener\">pubmed.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38877766\/#:~:text=vulgaris,and%20combined%20it%20with%20our\" target=\"_blank\" rel=\"noreferrer 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noopener\">fda.gov<\/a>\u3002\u5b9f\u969b\u3001AHA\u914d\u5408\u30af\u30ea\u30fc\u30e0\u4f7f\u7528\u8005\u3067\u306f\u65e5\u5149\u66dd\u9732\u5f8c\u306e\u7d05\u6591\u304c\u5f37\u307e\u308b\u3068\u306e\u5831\u544a\u304c\u3042\u308a\u3001\u30e6\u30fc\u30b6\u30fc\u6559\u80b2\u3068\u3057\u3066\u65e5\u4e2d\u306eSPF\u5bfe\u7b56\u3092\u6307\u5c0e\u3059\u3079\u304d\u3067\u3059<a href=\"https:\/\/www.fda.gov\/regulatory-information\/search-fda-guidance-documents\/guidance-industry-labeling-cosmetics-containing-alpha-hydroxy-acids#:~:text=Labeling%20for%20Cosmetics%20Containing%20Alpha,that%20this%20increased%20skin\" target=\"_blank\" rel=\"noreferrer noopener\">fda.gov<\/a>\u3002\u30b5\u30ea\u30c1\u30eb\u9178\u306f\u5e83\u7bc4\u56f2\u5857\u5e03\u3067\u7d4c\u76ae\u5438\u53ce\u3055\u308c\u308b\u3068\u4e2d\u67a2\u795e\u7d4c\u75c7\u72b6\u3092\u304d\u305f\u3059\u30ea\u30b9\u30af\u304c\u3042\u308b\u305f\u3081\uff08\u30b5\u30ea\u30c1\u30eb\u9178\u4e2d\u6bd2\uff09\u3001\u6fc3\u5ea6\u3068\u4f7f\u7528\u9762\u7a4d\u306b\u5236\u9650\u304c\u3042\u308a\u307e\u3059\u3002\u901a\u5e38\u5316\u7ca7\u54c1\u6fc3\u5ea6(0.5\uff5e2%)\u3067\u306f\u5b89\u5168\u3067\u3059\u304c\u3001\u654f\u611f\u808c\u3067\u306f\u30d2\u30ea\u30d2\u30ea\u3084\u4e7e\u71e5\u304c\u751f\u3058\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002\u30a4\u30aa\u30a6\u306f\u72ec\u7279\u306e\u81ed\u6c17\u304c\u3042\u308a\u3001\u4e00\u90e8\u3067\u63a5\u89e6\u76ae\u819a\u708e\uff08\u7279\u306b\u30b9\u30eb\u30d5\u30a1\u85ac\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u4eba\uff09\u3092\u8d77\u3053\u3057\u5f97\u307e\u3059\u3002\u4ee5\u4e0a\u306e\u9178\u7cfb\u30fb\u89d2\u8cea\u6eb6\u89e3\u7cfb\u6210\u5206\u306f\u3001<strong>\u4f5c\u7528\u304c\u5f37\u3044\u5206\u526f\u4f5c\u7528\u3082\u51fa\u3084\u3059\u3044<\/strong>\u305f\u3081\u3001\u808c\u72b6\u614b\u3092\u898b\u306a\u304c\u3089\u6e1b\u611f\u4f5c\u3055\u305b\u3066\u3044\u304f\u30a2\u30d7\u30ed\u30fc\u30c1\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p><strong>\u7f8e\u767d\u6210\u5206\u306e\u526f\u4f5c\u7528:<\/strong> 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vitro\u8a66\u9a13\u7d50\u679c\u3084\u3001\u5c0f\u898f\u6a21\u81e8\u5e8a\u8a66\u9a13\u306e\u7d71\u8a08\u30c7\u30fc\u30bf\u3092\u5546\u54c1\u30b5\u30a4\u30c8\u3067\u516c\u958b\u3057\u3001\u79d1\u5b66\u7684\u88cf\u4ed8\u3051\u3092\u91cd\u8996\u3059\u308b\u9867\u5ba2\u5c64\u306b\u30a2\u30d4\u30fc\u30eb\u3059\u308b\u624b\u6cd5\u3067\u3059\u3002\u4f8b\u3048\u3070\u300c\u25cb\u25cb\u6210\u5206\u914d\u5408\u30af\u30ea\u30fc\u30e0\u4f7f\u75288\u9031\u9593\u3067\u30b7\u30ef\u306e\u6df1\u305520%\u6e1b\u5c11<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11268769\/#:~:text=applications%20of%20AHAs%2C%20particularly%20in,Regulatory%20compliance%20is\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11268769\/#:~:text=analysis%20reveals%20a%20nuanced%20understanding,dermatology%2C%20emphasizing%20the%20necessity%20for\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u300d\u306a\u3069\u5177\u4f53\u7684\u6570\u5024\u3092\u793a\u3059\u30b1\u30fc\u30b9\u304c\u5897\u3048\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u4e00\u90e8\u3067\u306f\u7b2c\u4e09\u8005\u6a5f\u95a2\u306e\u8a66\u9a13\u3092\u53d7\u3051\u300c\u52b9\u679c\u691c\u8a3c\u6e08\u307f\u300d\u3068\u8868\u793a\u3059\u308b\u53d6\u308a\u7d44\u307f\u3082\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u306f\u6d88\u8cbb\u8005\u306e\u77e5\u8b58\u30ec\u30d9\u30eb\u5411\u4e0a\u306b\u5bfe\u5fdc\u3057\u305f\u3082\u306e\u3067\u3001\u7f8e\u5bb9\u76ae\u819a\u79d1\u533b\u306b\u3068\u3063\u3066\u3082\u88fd\u54c1\u9078\u629e\u6642\u306e\u91cd\u8981\u60c5\u5831\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u81e8\u5e8a\u7684\u6709\u7528\u6027\u3068\u30a8\u30d3\u30c7\u30f3\u30b9<\/h3>\n\n\n\n<p><strong>\u30a2\u30f3\u30c1\u30a8\u30a4\u30b8\u30f3\u30b0\u88fd\u54c1:<\/strong> 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href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11268769\/#:~:text=analysis%20reveals%20a%20nuanced%20understanding,dermatology%2C%20emphasizing%20the%20necessity%20for\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002\u30da\u30d7\u30c1\u30c9\u985e\u306f\u4f01\u696d\u767a\u8868\u306b\u4f9d\u5b58\u3059\u308b\u90e8\u5206\u304c\u5927\u304d\u304f\u3001\u7b2c\u4e09\u8005\u691c\u8a3c\u306f\u9650\u5b9a\u7684\u3067\u3059\u3002\u305f\u3060\u3001\u65b0\u5947\u30da\u30d7\u30c1\u30c9\u3068\u3057\u3066<strong>GHK-Cu<\/strong>\uff08\u9285\u30da\u30d7\u30c1\u30c9\uff09\u304c\u5275\u50b7\u6cbb\u7652\u4fc3\u9032\u3068\u30b7\u30ef\u6539\u5584\u306b\u52b9\u679c\u3068\u3044\u3046\u72ec\u7acb\u7814\u7a76\u3082\u3042\u308a\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u306f\u5f90\u3005\u306b\u6574\u3044\u3064\u3064\u3042\u308a\u307e\u3059\u3002\u7dcf\u3058\u3066\u30a2\u30f3\u30c1\u30a8\u30a4\u30b8\u30f3\u30b0\u6a5f\u80fd\u6027\u5316\u7ca7\u54c1\u306f<strong>\u30a8\u30d3\u30c7\u30f3\u30b9\u6c34\u6e96\u306f\u4e2d\u7a0b\u5ea6<\/strong>\u306a\u304c\u3089\u3001\u591a\u304f\u306e\u88fd\u54c1\u3067\u30e6\u30fc\u30b6\u30fc\u6e80\u8db3\u5ea6\u306e\u9ad8\u3044\u7d50\u679c\u304c\u5831\u544a\u3055\u308c\u3066\u304a\u308a\u3001\u5b9f\u5730\u8a3a\u7642\u3067\u3082\u30b9\u30ad\u30f3\u30b1\u30a2\u6307\u5c0e\u306b\u7d44\u307f\u8fbc\u3080\u4fa1\u5024\u304c\u3042\u308b\u3068\u3044\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u30cb\u30ad\u30d3\u30b1\u30a2\u88fd\u54c1:<\/strong> 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href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38877766\/#:~:text=Results%3A%20%20The%20quality%20of,as%20adjuncts%20to%20medical%20treatment\" target=\"_blank\" rel=\"noreferrer noopener\">pubmed.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38877766\/#:~:text=dermocosmetics%20in%20acne%20to%20improve,as%20adjuncts%20to%20medical%20treatment\" target=\"_blank\" rel=\"noreferrer noopener\">pubmed.ncbi.nlm.nih.gov<\/a>\u3002\u5177\u4f53\u7684\u306a\u30c7\u30fc\u30bf\u3067\u306f\u3001\u30b5\u30ea\u30c1\u30eb\u9178\u3084LHA\u3001\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9\u3001\u4e9c\u925b\u3001\u30ec\u30c1\u30ce\u30fc\u30eb\u7b49\u3092\u542b\u3080\u7f8e\u5bb9\u6db2\u3092\u5358\u72ec\u4f7f\u7528\u305712\u9031\u9593\u5f8c\u306b<strong>\u975e\u708e\u75c7\u6027\u75c5\u5909\u6570\u304c40\uff5e50%\u6e1b<\/strong>\u5c11\u3057\u305f\u5831\u544a\u3084<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=Open%E2%80%90label%2C%20split%20face%2C%20randomized%2C%20n,05%29%20at%20day%2028\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=Open%E2%80%90label%2C%20split%20face%2C%20randomized%2C%20n,05%29%20at%20day%2028\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3001BPO+\u30b5\u30ea\u30c1\u30eb\u9178\u4f75\u7528\u306e\u30b0\u30eb\u30fc\u30d7\u304c\u30b9\u30ad\u30f3\u30b1\u30a2\u5358\u72ec\u3088\u308a\u901f\u3084\u304b\u306a\u75c5\u5909\u6d88\u9000\u3092\u793a\u3057\u305f\u3068\u306eRCT\u7d50\u679c\u304c\u3042\u308a\u307e\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=Randomized%20open%E2%80%90label%2C%2056%20day%2C%20n,fastest%20and%20best%20clearance%20rates\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=%2B%20BPO%20versus%20BPO%201,fastest%20and%20best%20clearance%20rates\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002\u307e\u305f\u85ac\u7269\u6cbb\u7642\u4f75\u7528\u3067\u306f\u3001\u30a2\u30c0\u30d1\u30ec\u30f3\uff08\u51e6\u65b9\u30ec\u30c1\u30ce\u30a4\u30c9\uff09\uff0b\u4fdd\u6e7f\u5264 vs \u30a2\u30c0\u30d1\u30ec\u30f3\u5358\u72ec\u306e\u8a66\u9a13\u3067\u3001\u4fdd\u6e7f\u5264\u4f75\u7528\u7fa4\u306e\u65b9\u304c\u6cbb\u7642\u7d99\u7d9a\u7387\u304c\u9ad8\u304f\u3001\u76ae\u819a\u523a\u6fc0\u75c7\u72b6\u304c\u5c11\u306a\u3044\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=with%20moisturizer%20BID%20with%20salicylic,BPO%20QD%3B%20or%20BPO%20alone\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=1%20Improving%20tolerability%3A%20all%20groups,good%20tolerability%20but%20tolerability%20was\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002\u3064\u307e\u308a<strong>\u30b9\u30ad\u30f3\u30b1\u30a2\u4f75\u7528\u306f\u6cbb\u7642\u30a2\u30c9\u30d2\u30a2\u30e9\u30f3\u30b9\u3068\u5b89\u5168\u6027\u3092\u6539\u5584<\/strong>\u3057\u5f97\u308b\u306e\u3067\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=match%20at%20L1075%20with%20moisturizer,BPO%20QD%3B%20or%20BPO%20alone\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=with%20moisturizer%20BID%20with%20salicylic,BPO%20QD%3B%20or%20BPO%20alone\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002\u4ee5\u4e0a\u306e\u3088\u3046\u306b\u3001\u30cb\u30ad\u30d3\u30b1\u30a2\u30b3\u30b9\u30e1\u306e\u81e8\u5e8a\u6709\u7528\u6027\u306f\u9069\u5207\u306a\u6587\u8108\u3067\u9ad8\u304f\u3001\u7279\u306b\u601d\u6625\u671f\u60a3\u8005\u306e\u30bb\u30eb\u30d5\u30b1\u30a2\u78ba\u7acb\u3084\u3001\u6cbb\u7642\u7d42\u4e86\u5f8c\u306e\u30e1\u30f3\u30c6\u30ca\u30f3\u30b9\u671f\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u80b2\u6bdb\u30fb\u8584\u6bdb\u30b1\u30a2\u88fd\u54c1:<\/strong> 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vitro\u3067\u6bdb\u6bcd\u7d30\u80de\u5897\u6b96\u4fc3\u9032\u304c\u793a\u3055\u308c\u3001\u5973\u6027AGA\u60a3\u8005\u3067\u30ab\u30d5\u30a7\u30a4\u30f3\u30b7\u30e3\u30f3\u30d7\u30fc\u304c5%\u30df\u30ce\u30ad\u30b7\u30b8\u30eb\u5916\u7528\u30686\u304b\u6708\u5f8c\u306e\u52b9\u679c\u304c\u540c\u7b49\u3068\u306e\u4e88\u5099\u7684\u5831\u544a\u304c\u3042\u308a\u307e\u3059\u3002\u307e\u305f**\u30b1\u30c8\u30b3\u30ca\u30be\u30fc\u30eb\u30b7\u30e3\u30f3\u30d7\u30fc2%**\u306f\u6297\u771f\u83cc\u4f5c\u7528\u306b\u52a0\u3048\u6297\u708e\u75c7\u30fb\u6297\u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\u52b9\u679c\u304c\u3042\u308a\u30011998\u5e74\u306e\u30e9\u30f3\u30c0\u30e0\u5316\u8a66\u9a13\u3067\u306f2%\u30b1\u30c8\u30b3\u30ca\u30be\u30fc\u30eb\u30b7\u30e3\u30f3\u30d7\u30fc\u30923\u65e5\u306b1\u56de\u4f7f\u7528\u3057\u305f\u7fa4\u306f\u30012%\u30df\u30ce\u30ad\u30b7\u30b8\u30eb\u5916\u7528\u7fa4\u3068\u307b\u307c\u540c\u7b49\u306b\u9aea\u306e\u5bc6\u5ea6\u30fb\u592a\u3055\u304c\u6539\u5584\u3057\u307e\u3057\u305f<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9669136\/#:~:text=Results%3A%20%20Hair%20density%20and,to%20be%20decreased%20by%20KCZ\" target=\"_blank\" rel=\"noreferrer noopener\">pubmed.ncbi.nlm.nih.gov<\/a>\u30026\u30f6\u6708\u5f8c\u306e\u6bdb\u9aea\u5bc6\u5ea6\u4e0a\u6607\u7387\u304c\u4e21\u7fa4\u3067\u540c\u7a0b\u5ea6\u3067\u3042\u3063\u305f\u3053\u3068\u304b\u3089\u3001\u982d\u76ae\u306e\u30d5\u30b1\u30fb\u708e\u75c7\u3092\u6291\u3048\u308b\u3053\u3068\u3067\u6bdb\u5305\u74b0\u5883\u304c\u6539\u5584\u3057\u305f\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9669136\/#:~:text=Results%3A%20%20Hair%20density%20and,to%20be%20decreased%20by%20KCZ\" target=\"_blank\" rel=\"noreferrer noopener\">pubmed.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9669136\/#:~:text=appeared%20to%20be%20decreased%20by,KCZ\" target=\"_blank\" rel=\"noreferrer noopener\">pubmed.ncbi.nlm.nih.gov<\/a>\u3002\u305f\u3060\u3057\u3053\u306e\u7814\u7a76\u306f\u88ab\u9a13\u8005\u6570\u304c\u9650\u3089\u308c\u3001\u8ffd\u8a66\u3082\u5c11\u306a\u3044\u305f\u3081\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u30ec\u30d9\u30eb\u306f\u73fe\u6642\u70b9\u3067\u9ad8\u304f\u3042\u308a\u307e\u305b\u3093\u3002\u3057\u304b\u3057\u8fd1\u5e74\u300c\u30b1\u30c8\u30b3\u30ca\u30be\u30fc\u30eb\u30b7\u30e3\u30f3\u30d7\u30fc\u306fAGA\u6cbb\u7642\u306e\u88dc\u52a9\u305f\u308a\u5f97\u308b\u300d\u3068\u306e\u898b\u89e3\u3092\u793a\u3059\u76ae\u819a\u79d1\u533b\u3082\u304a\u308a<a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/jvc2.70026#:~:text=Role%20of%20Topical%20Ketoconazole%20in,likely%20due%20to%20its\" target=\"_blank\" rel=\"noreferrer noopener\">onlinelibrary.wiley.com<\/a><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/jvc2.70026#:~:text=,likely%20due%20to%20its\" target=\"_blank\" rel=\"noreferrer noopener\">onlinelibrary.wiley.com<\/a>\u3001<strong>\u88dc\u5b8c\u7642\u6cd5\u3068\u3057\u3066\u306e\u4fa1\u5024<\/strong>\u306f\u6a21\u7d22\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u4ed6\u3001<strong>\u30ad\u30e3\u30d4\u30ad\u30b7\u30eb<\/strong>\uff08\u30a2\u30bb\u30c1\u30eb\u30c6\u30c8\u30e9\u30da\u30d7\u30c1\u30c9-3\u3068\u30a2\u30ab\u30c4\u30e1\u30af\u30b5\u30a8\u30ad\u30b9\u306e\u8907\u5408\u4f53\uff09\u306f\u6bdb\u5305\u306e\u6210\u9577\u56e0\u5b50\u767a\u73fe\u3092\u4fc3\u3059\u3068\u3055\u308c\u3001\u4e00\u90e8\u306e\u81e8\u5e8a\u8a66\u9a13\u30674\u304b\u6708\u4f7f\u7528\u5f8c\u306b\u8edf\u6bdb\u5316\u3057\u305f\u6bdb\u9aea\u304c\u592a\u304f\u9577\u304f\u4f38\u3073\u308b\u50be\u5411\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3082\u4f01\u696d\u63d0\u4f9b\u30c7\u30fc\u30bf\u304c\u4e2d\u5fc3\u3067\u72ec\u7acb\u691c\u8a3c\u306f\u4e0d\u8db3\u3057\u3066\u3044\u307e\u3059\u3002<strong>\u4e9c\u925b\u30d4\u30ea\u30c1\u30aa\u30f3<\/strong>\u30b7\u30e3\u30f3\u30d7\u30fc\u306f\u30d5\u30b1\u9632\u6b62\u4ee5\u5916\u306bAGA\u6bdb\u9aea\u5f84\u5897\u5927\u52b9\u679c\u3092\u8a8d\u3081\u305f\u5c0f\u898f\u6a21\u8a66\u9a13\u304c\u3042\u308a\u307e\u3059<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9669136\/#:~:text=,density%3A%20a%20randomized%20controlled%20trial\" target=\"_blank\" rel=\"noreferrer noopener\">pubmed.ncbi.nlm.nih.gov<\/a>\uff08\u30d4\u30ea\u30c1\u30aa\u30f3\u4e9c\u925b\u3068\u30df\u30ce\u30ad\u30b7\u30b8\u30eb\u306e\u4f75\u7528\u3067\u76f8\u4e57\u52b9\u679c\u304c\u898b\u3089\u308c\u305f\u3068\u306e\u5831\u544a\uff09\u3002\u7dcf\u3058\u3066\u3001<strong>\u80b2\u6bdb\u5e02\u8ca9\u54c1\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u306f\u9650\u5b9a\u7684<\/strong>\u3067\u306f\u3042\u308b\u3082\u306e\u306e\u3001\u9069\u5207\u306a\u982d\u76ae\u30b1\u30a2\u304c\u629c\u3051\u6bdb\u9032\u884c\u3092\u7de9\u3084\u304b\u306b\u3059\u308b\u53ef\u80fd\u6027\u306f\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u7279\u306b\u8102\u6f0f\u6027\u76ae\u819a\u708e\u3092\u4f34\u3046AGA\u3067\u306f\u3001\u6297\u30d5\u30b1\u30b7\u30e3\u30f3\u30d7\u30fc\u3084\u6297\u708e\u75c7\u30ed\u30fc\u30b7\u30e7\u30f3\u3067\u982d\u76ae\u72b6\u614b\u3092\u6574\u3048\u308b\u3053\u3068\u306f\u6cbb\u7642\u30d9\u30fc\u30b9\u3068\u3057\u3066\u7406\u306b\u304b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u6a5f\u80fd\u6027\u7f8e\u767d\u5264:<\/strong> 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href=\"https:\/\/jcadonline.com\/study-depigmenting-agents-skin-color\/#:~:text=shown%20to%20be%20safe%20and,12%2C%2013\" target=\"_blank\" rel=\"noreferrer noopener\">jcadonline.com<\/a><a href=\"https:\/\/jcadonline.com\/study-depigmenting-agents-skin-color\/#:~:text=Topical%20niacinamide%20is%20believed%20to,lightening%20effect%20compared%20to%20hydroquinone\" target=\"_blank\" rel=\"noreferrer noopener\">jcadonline.com<\/a>\u3002\u7f8e\u5bb9\u76ae\u819a\u79d1\u3067\u306f\u3001\u60a3\u8005\u3054\u3068\u306b\u6709\u52b9\u6027\u3068\u523a\u6fc0\u6027\u306e\u30d0\u30e9\u30f3\u30b9\u3092\u8003\u616e\u3057\u3001\u533b\u7642\u7528\u30cf\u30a4\u30c9\u30ed\u30ad\u30ce\u30f3\u30fb\u30c8\u30ec\u30c1\u30ce\u30a4\u30f3\u306b\u983c\u3089\u305a\u3068\u3082\u7dad\u6301\u3067\u304d\u308b\u7d44\u307f\u5408\u308f\u305b\uff08\u4f8b\uff1a\u30d3\u30bf\u30df\u30f3C\uff0b\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9\uff0b\u65e5\u713c\u3051\u6b62\u3081\uff09\u3092\u8a66\u307f\u3066\u3001\u60a3\u8005\u306eQOL\u5411\u4e0a\u3092\u56f3\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u6700\u8fd1\u306e\u7814\u7a76\u52d5\u5411<\/h3>\n\n\n\n<p><strong>\u9769\u65b0\u7684\u6297\u8001\u5316\u7d20\u6750:<\/strong> 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href=\"https:\/\/www.frontiersin.org\/journals\/aging\/articles\/10.3389\/fragi.2025.1586999\/full#:~:text=marketing,applications%2C%20and%20recommends%20essential%20biomarkers\" target=\"_blank\" rel=\"noreferrer noopener\">frontiersin.org<\/a><a href=\"https:\/\/www.frontiersin.org\/journals\/aging\/articles\/10.3389\/fragi.2025.1586999\/full#:~:text=and%20modulate%20established%20hallmarks%20of,emphasize%20the%20importance%20of%20robust\" target=\"_blank\" rel=\"noreferrer noopener\">frontiersin.org<\/a>\u3002\u7f8e\u5bb9\u76ae\u819a\u79d1\u533b\u3082\u6700\u65b0\u306e\u7814\u7a76\u30c8\u30ec\u30f3\u30c9\u306b\u30a2\u30f3\u30c6\u30ca\u3092\u5f35\u308a\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u304c\u78ba\u7acb\u3057\u305f\u6bb5\u968e\u3067\u3044\u3061\u65e9\u304f\u53d6\u308a\u5165\u308c\u3066\u3044\u304f\u3053\u3068\u304c\u6c42\u3081\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u7537\u6027\u30b3\u30b9\u30e1\u7814\u7a76:<\/strong> 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class=\"wp-block-heading\">3. \u30e1\u30fc\u30af\u30a2\u30c3\u30d7\u9999\u7ca7\u54c1\uff08\u76ae\u819a\u3078\u306e\u5f71\u97ff\u3001\u5b89\u5168\u6027\u3001\u5149\u8001\u5316\u9632\u6b62\u306a\u3069\uff09<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">\u30e1\u30fc\u30af\u30a2\u30c3\u30d7\u88fd\u54c1\u306e\u7279\u5fb4\u3068\u76ae\u819a\u3078\u306e\u4f5c\u7528<\/h3>\n\n\n\n<p><strong>\u30e1\u30fc\u30af\u30a2\u30c3\u30d7\u5316\u7ca7\u54c1\u306e\u7a2e\u985e:<\/strong> 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href=\"https:\/\/jddonline.com\/high-coverage-makeup\/#:~:text=Currently%2C%20few%20sunscreens%20provide%20protection,harmful%20effects%20of%20that%20spectrum\" target=\"_blank\" rel=\"noreferrer noopener\">jddonline.com<\/a><a href=\"https:\/\/jddonline.com\/high-coverage-makeup\/#:~:text=containing%20pigments%20and%2For%20metal%20oxides,harmful%20effects%20of%20that%20spectrum\" target=\"_blank\" rel=\"noreferrer noopener\">jddonline.com<\/a>\u3002\u7279\u306b\u8fd1\u5e74\u306e\u30ea\u30ad\u30c3\u30c9\u30d5\u30a1\u30f3\u30c7\u30fc\u30b7\u30e7\u30f3\u306b\u306fSPF\u30fbPA\u5024\u304c\u4ed8\u4e0e\u3055\u308c\u3001\u65e5\u4e2d\u306eUV\u9632\u5fa1\u624b\u6bb5\u306e\u4e00\u3064\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u3055\u3089\u306b\u9854\u6599\u4e2d\u306e\u9178\u5316\u9244\u306f**\u53ef\u8996\u5149\uff08\u7279\u306b\u9752\u8272\u5149\uff09**\u3092\u906e\u65ad\u3057\u3001\u8272\u7d20\u6c88\u7740\u306e\u30ea\u30b9\u30af\u3092\u4f4e\u6e1b\u3057\u307e\u3059<a href=\"https:\/\/jddonline.com\/high-coverage-makeup\/#:~:text=Currently%2C%20few%20sunscreens%20provide%20protection,harmful%20effects%20of%20that%20spectrum\" target=\"_blank\" rel=\"noreferrer noopener\">jddonline.com<\/a><a href=\"https:\/\/jddonline.com\/high-coverage-makeup\/#:~:text=containing%20pigments%20and%2For%20metal%20oxides,harmful%20effects%20of%20that%20spectrum\" target=\"_blank\" rel=\"noreferrer noopener\">jddonline.com<\/a>\u3002\u4e8b\u5b9f\u3001\u6697\u3081\u306e\u30c8\u30fc\u30f3\u306e\u9ad8\u5bc6\u5ea6\u30d5\u30a1\u30f3\u30c7\u30fc\u30b7\u30e7\u30f3\u3092\u5857\u5e03\u3057\u305f\u5834\u5408\u3001SPF50\u306e\u65e5\u713c\u3051\u6b62\u3081\u4ee5\u4e0a\u306b\u53ef\u8996\u5149\u306b\u3088\u308b\u8272\u7d20\u6c88\u7740\u3092\u9632\u3052\u305f\u3068\u3059\u308b\u7814\u7a76\u3082\u3042\u308a\u307e\u3059<a href=\"https:\/\/jddonline.com\/high-coverage-makeup\/#:~:text=Here%2C%20we%20demonstrate%20that%20lightly,visual%20grading%20and%20by%20chromameter\" target=\"_blank\" rel=\"noreferrer noopener\">jddonline.com<\/a><a href=\"https:\/\/jddonline.com\/high-coverage-makeup\/#:~:text=Our%20results%20show%20the%20benefits,UV%20for%20multiple%20skin%20phototypes\" target=\"_blank\" rel=\"noreferrer noopener\">jddonline.com<\/a>\u3002\u3053\u306e\u3088\u3046\u306b\u30e1\u30fc\u30af\u30a2\u30c3\u30d7\u88fd\u54c1\u306f\u5be9\u7f8e\u7684\u52b9\u679c\u3060\u3051\u3067\u306a\u304f\u3001<strong>\u4fdd\u8b77\u819c<\/strong>\u3068\u3057\u3066\u5916\u7684\u30b9\u30c8\u30ec\u30b9\uff08\u7d2b\u5916\u7dda\u3001\u6c5a\u67d3\u7269\u8cea\u306a\u3069\uff09\u304b\u3089\u76ae\u819a\u3092\u5b88\u308b\u5074\u9762\u3082\u6301\u3061\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u76ae\u819a\u3078\u306e\u7269\u7406\u30fb\u5316\u5b66\u7684\u5f71\u97ff:<\/strong> 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href=\"https:\/\/www.aad.org\/public\/diseases\/acne\/causes\/makeup#:~:text=Some%20cosmetics%20can%20cause%20acne,makeup%2C%20but%20still%20avoid%20acne\" target=\"_blank\" rel=\"noreferrer noopener\">aad.org<\/a><a href=\"https:\/\/www.aad.org\/public\/diseases\/acne\/causes\/makeup#:~:text=Some%20cosmetics%20can%20cause%20acne,makeup%2C%20but%20still%20avoid%20acne\" target=\"_blank\" rel=\"noreferrer noopener\">aad.org<\/a>\u3002\u5b9f\u969b\u3001\u8fd1\u5e74\u306e\u5927\u898f\u6a21\u8abf\u67fb\u3067\u306f\u300c\u5316\u7ca7\u7fd2\u6163\u3068\u30cb\u30ad\u30d3\u91cd\u75c7\u5ea6\u306b\u9006\u95a2\u9023\u304c\u3042\u308b\u300d\uff08=\u5316\u7ca7\u3092\u3088\u304f\u3059\u308b\u5973\u6027\u306e\u65b9\u304c\u30cb\u30ad\u30d3\u304c\u5c11\u306a\u3044\uff09\u3068\u306e\u7d50\u679c\u3082\u51fa\u3066\u304a\u308a<a href=\"https:\/\/www.ijord.com\/index.php\/ijord\/article\/view\/1911#:~:text=Acne%20Cosmetica%20Revisited%3A%20A%20Case,Adolescent%20Acne.%20Dermatology\" target=\"_blank\" rel=\"noreferrer noopener\">ijord.com<\/a>\u3001\u3053\u308c\u306f\u30e1\u30fc\u30af\u3059\u308b\u4eba\u306f\u30b9\u30ad\u30f3\u30b1\u30a2\u3082\u4e01\u5be7\u306a\u305f\u3081\u3068\u63a8\u6e2c\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3064\u307e\u308a\u5316\u7ca7\u305d\u306e\u3082\u306e\u304c\u5fc5\u305a\u3057\u3082\u30cb\u30ad\u30d3\u3092\u60aa\u5316\u3055\u305b\u308b\u308f\u3051\u3067\u306f\u306a\u304f\u3001\u3080\u3057\u308d<strong>\u4e0d\u9069\u5207\u306a\u30e1\u30fc\u30af\u843d\u3068\u3057<\/strong>\uff08\u5316\u7ca7\u304c\u6bdb\u7a74\u306b\u6b8b\u7559\uff09\u3084<strong>\u6cb9\u6027\u306e\u30d8\u30a2\u88fd\u54c1<\/strong>\uff08\u9aea\u5468\u308a\u306e\u6bdb\u5b54\u3092\u585e\u3050\uff09\u304c\u539f\u56e0\u3068\u306a\u308b\u3053\u3068\u304c\u591a\u3044\u3067\u3059\u3002\u4ee5\u4e0a\u3088\u308a\u3001\u30e1\u30fc\u30af\u30a2\u30c3\u30d7\u88fd\u54c1\u306f\u6b63\u3057\u304f\u4f7f\u3048\u3070\u76ae\u819a\u3078\u306e\u60aa\u5f71\u97ff\u306f\u6700\u5c0f\u9650\u306b\u6291\u3048\u3089\u308c\u307e\u3059\u304c\u3001<strong>\u30e1\u30fc\u30af\u3068\u30aa\u30d5\u306e\u30d0\u30e9\u30f3\u30b9<\/strong>\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u5149\u8001\u5316\u9632\u6b62\u52b9\u679c<\/h3>\n\n\n\n<p>\u30e1\u30fc\u30af\u30a2\u30c3\u30d7\u306b\u3088\u308b<strong>\u30d5\u30a9\u30c8\u30d7\u30ed\u30c6\u30af\u30b7\u30e7\u30f3\uff08\u5149\u9632\u8b77\uff09\u306f\u76ae\u819a\u79d1\u5b66\u7684\u306b\u3082\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u30d5\u30a1\u30f3\u30c7\u30fc\u30b7\u30e7\u30f3\u3084\u30d5\u30a7\u30a4\u30b9\u30d1\u30a6\u30c0\u30fc\u306b\u542b\u307e\u308c\u308b\u9178\u5316\u30c1\u30bf\u30f3\u3084\u9178\u5316\u4e9c\u925b\u306f\u7269\u7406\u7684\u7d2b\u5916\u7dda\u6563\u4e71\u5264\u3067\u3042\u308a\u3001\u5e83\u7bc4\u56f2\u306eUV\u3092\u53cd\u5c04\u3057\u307e\u3059\u3002\u307e\u305f\u30e1\u30fc\u30af\u306e\u9854\u6599\u5c64\u304c\u3042\u308b\u3053\u3068\u3067\u7d2b\u5916\u7dda\u306e\u4e00\u90e8\u306f\u808c\u306b\u5c4a\u304b\u305a\u3001\u305d\u306e\u4e0b\u306eUV\u30ab\u30c3\u30c8\u88fd\u54c1\u306e\u52b9\u679c\u3082\u9ad8\u307e\u308a\u307e\u3059\u30022021\u5e74\u306e\u7814\u7a76\u3067\u306f\u3001\u65e5\u713c\u3051\u6b62\u3081\u5358\u72ec\u5857\u5e03\u6642\u3068\u305d\u306e\u4e0a\u306b\u30d5\u30a1\u30f3\u30c7\u30fc\u30b7\u30e7\u30f3\u3092\u91cd\u306d\u305f\u5834\u5408\u306eSPF\u52b9\u679c\u3092\u6bd4\u8f03\u3057\u3001\u91cd\u306d\u5857\u308a\u306b\u3088\u308a\u5b9f\u4f7f\u7528\u4e0b\u306e\u5b9f\u52b9SPF\u304c\u5411\u4e0a\u3059\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33660348\/#:~:text=Results%3A%20%20The%20SPF%20of,was%20below%20the%20recommended%20level\" target=\"_blank\" rel=\"noreferrer noopener\">pubmed.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33660348\/#:~:text=products%20greatly%20increased%20the%20effective,was%20below%20the%20recommended%20level\" target=\"_blank\" rel=\"noreferrer noopener\">pubmed.ncbi.nlm.nih.gov<\/a>\u3002\u7279\u306b\u4e00\u822c\u6d88\u8cbb\u8005\u306f\u65e5\u713c\u3051\u6b62\u3081\u3092\u898f\u5b9a\u91cf\u3088\u308a\u5c11\u306a\u304f\u5857\u308a\u304c\u3061\u3067\u3059\u304c\u3001\u305d\u306e\u4e0a\u306b\u30d5\u30a1\u30f3\u30c7\u30fc\u30b7\u30e7\u30f3\u3092\u91cd\u306d\u308b\u3053\u3068\u3067\u8db3\u308a\u306a\u3044\u91cf\u3092\u88dc\u3044\u3001\u7d50\u679c\u7684\u306b\u7d2b\u5916\u7dda\u9632\u5fa1\u529b\u304c\u9ad8\u307e\u308b\u3068\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33660348\/#:~:text=Results%3A%20%20The%20SPF%20of,was%20below%20the%20recommended%20level\" target=\"_blank\" rel=\"noreferrer noopener\">pubmed.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33660348\/#:~:text=was%20below%20the%20recommended%20level\" target=\"_blank\" rel=\"noreferrer noopener\">pubmed.ncbi.nlm.nih.gov<\/a>\u3002\u3055\u3089\u306b\u524d\u8ff0\u306e\u3088\u3046\u306b\u9178\u5316\u9244\u914d\u5408\u306e\u8272\u4ed8\u304d\u30d5\u30a1\u30f3\u30c7<\/strong>\u306fUV\u306e\u307f\u306a\u3089\u305a\u53ef\u8996\u5149\u7dda\u3082\u906e\u65ad\u3057\u3001<strong>\u808c\u306e\u8272\u7d20\u6c88\u7740\u3092\u9632\u3050<\/strong>\u52b9\u679c\u304c\u3042\u308a\u307e\u3059\u3002\u5b9f\u969b\u3001\u30d5\u30a3\u30c3\u30c4\u30d1\u30c8\u30ea\u30c3\u30afIV\u578b\u4ee5\u4e0a\u306e\u808c\u3067\u306f\u53ef\u8996\u5149\u304c\u809d\u6591\u3084\u708e\u75c7\u5f8c\u8272\u7d20\u6c88\u7740\u3092\u60aa\u5316\u3055\u305b\u308b\u4e00\u56e0\u3068\u306a\u308a\u307e\u3059\u304c\u3001\u9244\u5206\u3092\u542b\u3080\u7740\u8272\u5316\u7ca7\u54c1\u306e\u4f7f\u7528\u3067\u3053\u308c\u3092\u6291\u5236\u3067\u304d\u308b\u3068\u306e\u5831\u544a\u304c\u3042\u308a\u307e\u3059<a href=\"https:\/\/jddonline.com\/high-coverage-makeup\/#:~:text=Currently%2C%20few%20sunscreens%20provide%20protection,harmful%20effects%20of%20that%20spectrum\" target=\"_blank\" rel=\"noreferrer noopener\">jddonline.com<\/a><a href=\"https:\/\/jddonline.com\/high-coverage-makeup\/#:~:text=containing%20pigments%20and%2For%20metal%20oxides,harmful%20effects%20of%20that%20spectrum\" target=\"_blank\" rel=\"noreferrer noopener\">jddonline.com<\/a>\u3002\u9854\u6599\u6fc3\u5ea6\u306e\u9ad8\u3044\u30b3\u30f3\u30b7\u30fc\u30e9\u30fc\u3084\u821e\u53f0\u7528\u30d5\u30a1\u30f3\u30c7\u30fc\u30b7\u30e7\u30f3\u306f\u7279\u306b\u9632\u5fa1\u52b9\u679c\u304c\u5927\u304d\u304f\u3001\u30a2\u30a6\u30c8\u30c9\u30a2\u6d3b\u52d5\u6642\u306a\u3069\u306b\u7a4d\u6975\u7684\u306b\u5229\u7528\u3059\u308b\u306e\u3082\u4e00\u6cd5\u3067\u3059\u3002\u305f\u3060\u3057\u6ce8\u610f\u70b9\u3068\u3057\u3066\u3001\u30e1\u30fc\u30af\u88fd\u54c1\u306e\u9632\u5fa1\u52b9\u679c\u306f<strong>\u5857\u5e03\u91cf\u3084\u539a\u3055<\/strong>\u306b\u5de6\u53f3\u3055\u308c\u307e\u3059\u3002\u4e00\u822c\u306b\u65e5\u713c\u3051\u6b62\u3081\u306e\u3088\u3046\u306b\u539a\u5857\u308a\u306f\u3057\u306a\u3044\u305f\u3081\u3001\u88fd\u54c1\u8868\u793a\u306eSPF\u5024\u307b\u3069\u306e\u52b9\u679c\u306f\u5f97\u3089\u308c\u306b\u304f\u3044\u3067\u3059<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33660348\/#:~:text=Results%3A%20%20The%20SPF%20of,was%20below%20the%20recommended%20level\" target=\"_blank\" rel=\"noreferrer noopener\">pubmed.ncbi.nlm.nih.gov<\/a>\u3002\u305d\u308c\u3067\u3082SPF15\u7a0b\u5ea6\u306e\u30d5\u30a1\u30f3\u30c7\u3092\u5168\u9854\u306b\u8584\u304f\u4f38\u3070\u3059\u3060\u3051\u3067\u3001\u4f55\u3082\u5857\u3089\u306a\u3044\u7d20\u808c\u3088\u308a\u7d2b\u5916\u7dda\u66b4\u9732\u306f\u6e1b\u308a\u307e\u3059\u3002\u52a0\u3048\u3066\u30d1\u30a6\u30c0\u30fc\u304a\u3057\u308d\u3044\u306e\u91cd\u306d\u4ed8\u3051\u306f<strong>SPF\u30d6\u30fc\u30b9\u30bf\u30fc<\/strong>\u3068\u3057\u3066\u6709\u52b9\u3067\u3059\u3002\u7c73\u56fd\u76ae\u819a\u79d1\u5b66\u4f1a\u3082\u300c\u30e1\u30fc\u30af\u30a2\u30c3\u30d7\u306f\u7d2b\u5916\u7dda\u9632\u5fa1\u306e\u88dc\u52a9\u306b\u306a\u308b\u304c\u3001\u5358\u4f53\u306b\u983c\u3089\u305a\u65e5\u713c\u3051\u6b62\u3081\u3068\u4f75\u7528\u3059\u3079\u304d\u300d\u3068\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3067\u8ff0\u3079\u3066\u3044\u307e\u3059\u3002\u7dcf\u3058\u3066\u3001\u30e1\u30fc\u30af\u30a2\u30c3\u30d7\u306f<strong>\u65e5\u4e2d\u306e\u808c\u3092\u5b88\u308b\u93a7<\/strong>\u3068\u3057\u3066\u50cd\u304d\u3001\u5149\u8001\u5316\u4e88\u9632\u306b\u5bc4\u4e0e\u3057\u307e\u3059\u3002\u305f\u3060\u3001\u7d2b\u5916\u7dda\u6563\u4e71\u5264\u3092\u542b\u3080\u30e1\u30fc\u30af\u306f\u3057\u3063\u304b\u308a\u843d\u3068\u3059\u5fc5\u8981\u304c\u3042\u308a\u3001\u591c\u306e\u30af\u30ec\u30f3\u30b8\u30f3\u30b0\u3067\u808c\u306b\u6b8b\u3055\u306a\u3044\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u76ae\u819a\u5b89\u5168\u6027\u3068\u30c8\u30e9\u30d6\u30eb<\/h3>\n\n\n\n<p><strong>\u306b\u304d\u3073\u30fb\u6bdb\u7a74\u3078\u306e\u5f71\u97ff:<\/strong> \u304b\u3064\u3066\u300c\u7c89\u8102\u6027\u3056\u7621\uff08acne cosmetica\uff09\u300d\u3068\u547c\u3070\u308c\u308b\u3001\u5316\u7ca7\u54c1\u306e\u9577\u671f\u4f7f\u7528\u306b\u3088\u308b\u9762\u76b0\u4e3b\u4f53\u306e\u30cb\u30ad\u30d3\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3057\u305f\u3002\u7279\u306b\u6cb9\u5206\u306e\u591a\u3044\u30d5\u30a1\u30f3\u30c7\u30fc\u30b7\u30e7\u30f3\u3084\u30dd\u30de\u30fc\u30c9\u306a\u3069\u306e\u4f7f\u7528\u3067\u984d\u3084\u982c\u306b\u7d30\u304b\u3044\u9762\u76b0\u304c\u591a\u767a\u3059\u308b\u30b1\u30fc\u30b9\u3067\u3059\u3002\u3057\u304b\u3057\u73fe\u4ee3\u3067\u306f\u30e1\u30fc\u30af\u88fd\u54c1\u306e\u591a\u304f\u304c\u30ce\u30f3\u30b3\u30e1\u30c9\u30b8\u30a7\u30cb\u30c3\u30af\u30c6\u30b9\u30c8\u3092\u30d1\u30b9\u3057\u3066\u304a\u308a\u3001\u5065\u5e38\u8005\u304c\u666e\u901a\u306b\u4f7f\u3046\u7bc4\u56f2\u3067\u30cb\u30ad\u30d3\u3092\u9855\u8457\u306b\u60aa\u5316\u3055\u305b\u308b\u3053\u3068\u306f\u7a00\u3067\u3059<a href=\"https:\/\/www.aad.org\/public\/diseases\/acne\/causes\/makeup#:~:text=Some%20cosmetics%20can%20cause%20acne,makeup%2C%20but%20still%20avoid%20acne\" target=\"_blank\" rel=\"noreferrer noopener\">aad.org<\/a>\u3002\u3080\u3057\u308d\u5148\u8ff0\u306e\u3088\u3046\u306b\u9069\u5207\u306a\u30b9\u30ad\u30f3\u30b1\u30a2\u3068\u30af\u30ec\u30f3\u30b8\u30f3\u30b0\u3092\u5fc3\u304c\u3051\u308b\u4eba\u307b\u3069\u30cb\u30ad\u30d3\u72b6\u614b\u304c\u826f\u3044\u50be\u5411\u3059\u3089\u3042\u308a\u307e\u3059<a href=\"https:\/\/www.ijord.com\/index.php\/ijord\/article\/view\/1911#:~:text=Acne%20Cosmetica%20Revisited%3A%20A%20Case,Adolescent%20Acne.%20Dermatology\" target=\"_blank\" rel=\"noreferrer noopener\">ijord.com<\/a>\u3002\u305f\u3060\u3057\u3001\u975e\u5e38\u306b\u30b3\u30f3\u30d4\u30af\uff08\u6bdb\u7a74\u9589\u585e\u6027\uff09\u306e\u9ad8\u3044\u6210\u5206\uff08\u30e9\u30ce\u30ea\u30f3\u3001\u91cd\u305f\u3044\u690d\u7269\u6cb9\u3001\u9ad8\u6fc3\u5ea6\u306e\u30bf\u30fc\u30eb\u8272\u7d20\u306a\u3069\uff09\u306f\u3001\u30cb\u30ad\u30d3\u808c\u3067\u306f\u907f\u3051\u308b\u65b9\u304c\u7121\u96e3\u3067\u3059\u3002\u88fd\u54c1\u9078\u629e\u6642\u306b\u306f\u300c\u30ce\u30f3\u30b3\u30e1\u30c9\u30b8\u30a7\u30cb\u30c3\u30af\u51e6\u65b9\u300d\u306e\u8868\u793a\u3084\u3001\u76ae\u819a\u79d1\u533b\u76e3\u4fee\u30c6\u30b9\u30c8\u6e08\u307f\u306a\u3069\u5b89\u5168\u6027\u60c5\u5831\u3092\u78ba\u8a8d\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u523a\u6fc0\u6027\u30fb\u30a2\u30ec\u30eb\u30ae\u30fc:<\/strong> 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rel=\"noreferrer noopener\">pubmed.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33660348\/#:~:text=products%20greatly%20increased%20the%20effective,was%20below%20the%20recommended%20level\" target=\"_blank\" rel=\"noreferrer noopener\">pubmed.ncbi.nlm.nih.gov<\/a>\u3002\u307e\u305f\u53ef\u8996\u5149\u306b\u3088\u308b\u8272\u7d20\u6c88\u7740\u30ea\u30b9\u30af\u306b\u3064\u3044\u3066\u3001\u6697\u8272\u7cfb\u30d5\u30a1\u30f3\u30c7\u30fc\u30b7\u30e7\u30f3\uff08\u9178\u5316\u9244\u542b\u6709\uff09\u304c\u5149\u9632\u5fa1\u306b\u6709\u52b9\u3068\u306e\u30c7\u30fc\u30bf\u304c\u84c4\u7a4d\u3057\u3066\u3044\u307e\u3059\u30022020\u5e74\u306eSkin of Color\u30ab\u30f3\u30d5\u30a1\u30ec\u30f3\u30b9\u306e\u767a\u8868\u3067\u306f\u3001\u30d5\u30a3\u30c3\u30c4\u30d1\u30c8\u30ea\u30c3\u30afIV\u578b\u306e\u88ab\u9a13\u8005\u306b\u304a\u3044\u3066\u3001<strong>\u9ad8\u6fc3\u5ea6\u9854\u6599\u30d5\u30a1\u30f3\u30c7\u304cSPF50+\u65e5\u713c\u3051\u6b62\u3081\u3088\u308a\u3082\u53ef\u8996\u5149\u8a98\u767a\u306e\u8272\u7d20\u6c88\u7740\u3092\u6709\u610f\u306b\u6291\u5236<\/strong>\u3057\u305f\u3068\u5831\u544a\u3055\u308c\u307e\u3057\u305f<a href=\"https:\/\/jddonline.com\/high-coverage-makeup\/#:~:text=Currently%2C%20few%20sunscreens%20provide%20protection,harmful%20effects%20of%20that%20spectrum\" target=\"_blank\" rel=\"noreferrer noopener\">jddonline.com<\/a><a href=\"https:\/\/jddonline.com\/high-coverage-makeup\/#:~:text=containing%20pigments%20and%2For%20metal%20oxides,harmful%20effects%20of%20that%20spectrum\" target=\"_blank\" rel=\"noreferrer noopener\">jddonline.com<\/a>\u3002\u3053\u306e\u3088\u3046\u306a\u77e5\u898b\u306f\u3001\u7279\u306b\u8272\u7d20\u6c88\u7740\u6cbb\u7642\u4e2d\u306e\u60a3\u8005\u6559\u80b2\u306b\u5f79\u7acb\u3061\u307e\u3059\u3002\u300c\u6cbb\u7642\u90e8\u4f4d\u306b\u65e5\u4e2d\u30d5\u30a1\u30f3\u30c7\u30fc\u30b7\u30e7\u30f3\u3092\u5857\u3063\u3066\u30ab\u30d0\u30fc\u3059\u308b\u3053\u3068\u81ea\u4f53\u304c\u6cbb\u7642\u3092\u52a9\u3051\u308b\u300d\u3068\u8aac\u660e\u3059\u308b\u3053\u3068\u3067\u3001\u60a3\u8005\u306e\u5354\u529b\u3082\u5f97\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u808c\u6a5f\u80fd\u3078\u306e\u5f71\u97ff\u7814\u7a76:<\/strong> 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class=\"wp-block-heading\">\u6700\u8fd1\u306e\u7814\u7a76\u52d5\u5411<\/h3>\n\n\n\n<p><strong>\u808c\u8a08\u6e2c\u6280\u8853\u3068\u30e1\u30fc\u30af:<\/strong> 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COVID-19\u6d41\u884c\u4e0b\u3067\u30de\u30b9\u30af\u751f\u6d3b\u304c\u5e38\u614b\u5316\u3057\u305f\u3053\u3068\u3067\u3001\u30dd\u30a4\u30f3\u30c8\u30e1\u30a4\u30af\uff08\u76ee\u5143\u91cd\u8996\uff09\u3084<strong>\u30de\u30b9\u30af\u5bfe\u5fdc\u30d5\u30a1\u30f3\u30c7<\/strong>\u306e\u958b\u767a\u304c\u76db\u3093\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u4f8b\u3048\u3070\u534a\u9854\u3060\u3051\u30d5\u30a1\u30f3\u30c7\u3092\u5857\u308b\u300c\u30aa\u30f3\u30fb\u30aa\u30d5\u30e1\u30fc\u30af\u300d\uff08\u30de\u30b9\u30af\u3067\u96a0\u308c\u308b\u4e0b\u534a\u9854\u306f\u65e5\u713c\u3051\u6b62\u3081\u306e\u307f\u306b\u3059\u308b\uff09\u63d0\u6848\u3084\u3001\u30de\u30b9\u30af\u84b8\u308c\u3067\u5d29\u308c\u306b\u304f\u3044\u51e6\u65b9\uff08\u76ae\u8102\u5438\u53ce\u7c89\u672b\u5897\u91cf\u3001\u30d5\u30a3\u30eb\u30e0\u5f62\u6210\u5264\u914d\u5408\uff09\u306a\u3069\u304c\u7814\u7a76\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u30de\u30b9\u30af\u5185\u306f\u9ad8\u6e7f\u5ea6\u306a\u305f\u3081\u3001\u30d5\u30a1\u30f3\u30c7\u304c\u30e8\u30ec\u306b\u304f\u304f\u30d5\u30a3\u30c3\u30c8\u3059\u308b\u30d5\u30a9\u30fc\u30df\u30e5\u30e9\u306e\u63a2\u6c42\u304c\u9032\u307f\u30012021\u5e74\u9803\u304b\u3089\u5404\u793e\u304c\u300c\u30de\u30b9\u30af\u306b\u3064\u304b\u306a\u3044\u30d5\u30a1\u30f3\u30c7\u300d\u3092\u58f2\u308a\u51fa\u3057\u307e\u3057\u305f\u3002\u30a8\u30d3\u30c7\u30f3\u30b9\u7684\u306b\u306f\u3001\u5bc6\u7740\u5ea6\u8a66\u9a13\u3067\u5f93\u6765\u54c1\u3088\u308a30-50%\u79fb\u308a\u304c\u6e1b\u3063\u305f\u3068\u3059\u308b\u30c7\u30fc\u30bf\u304c\u63d0\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305f\u3060\u4f9d\u7136\u5b8c\u74a7\u3067\u306f\u306a\u304f\u3001\u30de\u30b9\u30af\u5074\u306e\u5185\u7d20\u6750\u5de5\u592b\uff08\u30b7\u30eb\u30af\u3084\u5438\u6c34\u7d19\u3092\u3042\u3066\u308b\u7b49\uff09\u3068\u306e\u4f75\u7528\u304c\u63d0\u5531\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u30a2\u30ec\u30eb\u30b2\u30f3\u30d5\u30ea\u30fc\u3078\u306e\u6311\u6226:<\/strong> 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class=\"wp-block-heading\">\u4f5c\u7528\u6a5f\u5e8f\u3068\u81e8\u5e8a\u52b9\u679c<\/h3>\n\n\n\n<p><strong>\u6bdb\u9aea\u4fee\u5fa9\u30fb\u30b3\u30f3\u30c7\u30a3\u30b7\u30e7\u30cb\u30f3\u30b0:<\/strong> \u6bdb\u9aea\u306f\u6b7b\u7d30\u80de\u306e\u89d2\u5316\u7269\u3067\u81ea\u5df1\u4fee\u5fa9\u80fd\u304c\u7121\u3044\u305f\u3081\u3001\u5316\u7ca7\u54c1\u3067\u306e\u300c\u4fee\u5fa9\u300d\u306f\u7269\u7406\u7684\u30fb\u5316\u5b66\u7684\u306b\u30c0\u30e1\u30fc\u30b8\u90e8\u5206\u3092\u57cb\u3081\u305f\u308a\u30b3\u30fc\u30c6\u30a3\u30f3\u30b0\u3059\u308b\u3053\u3068\u3092\u610f\u5473\u3057\u307e\u3059\u3002\u30b7\u30ea\u30b3\u30fc\u30f3\u3084\u6cb9\u5206\u306f\u758e\u6c34\u7684\u88ab\u819c\u3092\u4f5c\u308a\u3001\u30d6\u30e9\u30c3\u30b7\u30f3\u30b0\u3084\u6469\u64e6\u306b\u3088\u308b\u30ad\u30e5\u30fc\u30c6\u30a3\u30af\u30eb\u5265\u96e2\u3092\u6e1b\u3089\u3057\u307e\u3059\u3002\u307e\u305f\u6fe1\u308c\u305f\u9aea\u306f\u30ad\u30e5\u30fc\u30c6\u30a3\u30af\u30eb\u304c\u958b\u304d\u30bf\u30f3\u30d1\u30af\u304c\u6d41\u51fa\u3057\u3084\u3059\u3044\u3067\u3059\u304c\u3001\u30b3\u30f3\u30c7\u30a3\u30b7\u30e7\u30ca\u30fc\u6210\u5206\u304c\u7d50\u5408\u3059\u308b\u3053\u3068\u3067\u6d41\u51fa\u3092\u6291\u3048\u307e\u3059\u3002\u5b9f\u9a13\u3067\u306f\u3001\u30b3\u30f3\u30c7\u30a3\u30b7\u30e7\u30ca\u30fc\u4f7f\u7528\u306b\u3088\u308a<strong>\u30b3\u30fc\u30df\u30f3\u30b0\u6642\u306e\u6469\u64e6\u529b\u304c\u5927\u5e45\u306b\u4f4e\u4e0b<\/strong>\u3057\u3001\u7d50\u679c\u3068\u3057\u3066\u679d\u6bdb\u30fb\u5207\u308c\u6bdb\u304c\u6709\u610f\u306b\u6e1b\u5c11\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u52a0\u6c34\u5206\u89e3\u30b1\u30e9\u30c1\u30f3\u306a\u3069\u306e\u4f4e\u5206\u5b50\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u6bdb\u9aea\u5185\u90e8\u306b\u4e00\u90e8\u6d78\u900f\u3057\u3001\u30c0\u30e1\u30fc\u30b8\u30db\u30fc\u30eb\u306b\u7d50\u5408\u3057\u3066\u9aea\u306e\u5f37\u5ea6\u3092\u5411\u4e0a\u3055\u305b\u308b\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u9aea\u306epH\u30924.5-5.5\u7a0b\u5ea6\u306e\u5f31\u9178\u6027\u306b\u4fdd\u3064\u3053\u3068\u3082\u30ad\u30e5\u30fc\u30c6\u30a3\u30af\u30eb\u3092\u9589\u3058\u3066\u30c4\u30e4\u3068\u5f37\u5ea6\u3092\u4fdd\u3064\u4e0a\u3067\u91cd\u8981\u3067\u3001\u9178\u30ea\u30f3\u30b9\uff08\u30af\u30a8\u30f3\u9178\u914d\u5408\u30ea\u30f3\u30b9\uff09\u304c\u53e4\u304f\u304b\u3089\u77e5\u3089\u308c\u307e\u3059\u3002\u7dcf\u3058\u3066\u3001\u30d8\u30a2\u30b3\u30f3\u30c7\u30a3\u30b7\u30e7\u30cb\u30f3\u30b0\u6210\u5206\u306f<strong>\u529b\u5b66\u7684\u30c0\u30e1\u30fc\u30b8\u3092\u4f4e\u6e1b<\/strong>\u3057\u3001\u9aea\u306e\u8276\u3084\u624b\u89e6\u308a\u3092\u6539\u5584\u3059\u308b\u3053\u3068\u3067\u81e8\u5e8a\u7684\u30fb\u5be9\u7f8e\u7684\u6709\u7528\u6027\u304c\u9ad8\u3044\u3068\u3044\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u80b2\u6bdb\u4f5c\u7528:<\/strong> \u533b\u85ac\u90e8\u5916\u54c1\u306e\u80b2\u6bdb\u5264\u306f\u300c\u9aea\u3092\u5065\u3084\u304b\u306b\u4fdd\u3064\u300d\u300c\u629c\u3051\u6bdb\u3092\u9632\u3050\u300d\u306a\u3069\u6bd4\u8f03\u30de\u30a4\u30eb\u30c9\u306a\u52b9\u80fd\u3067\u3059\u304c\u3001\u305d\u306e\u4f5c\u7528\u6a5f\u5e8f\u306f\u6982\u306d\u4ee5\u4e0b\u3067\u3059\u3002(1)\u8840\u884c\u4fc3\u9032\uff1a\u30cb\u30b3\u30c1\u30f3\u9178\u30d9\u30f3\u30b8\u30eb\u306a\u3069\u3067\u982d\u76ae\u306e\u8840\u6d41\u3092\u5897\u3084\u3057\u6bdb\u6839\u3078\u306e\u6804\u990a\u4f9b\u7d66\u3092\u6539\u5584\u3002(2)\u6804\u990a\u88dc\u7d66\uff1a\u5404\u7a2e\u30d3\u30bf\u30df\u30f3\u3084\u30a2\u30df\u30ce\u9178\u3067\u6bdb\u6bcd\u7d30\u80de\u306e\u4ee3\u8b1d\u3092\u30b5\u30dd\u30fc\u30c8\u3002(3)\u6297\u708e\u75c7\uff1a\u30d5\u30b1\u3084\u76ae\u8102\u306b\u3088\u308b\u708e\u75c7\u3092\u30b0\u30ea\u30c1\u30eb\u30ea\u30c1\u30f3\u9178\u7b49\u3067\u6291\u3048\u308b\u3002(4)\u7d30\u80de\u523a\u6fc0\uff1a\u30bb\u30f3\u30d6\u30ea\u30a8\u30ad\u30b9\u7b49\u304c\u6bdb\u4e73\u982d\u3092\u523a\u6fc0\u3059\u308b\u53ef\u80fd\u6027\u3002\u3053\u308c\u3089\u306b\u3088\u308a<strong>\u6bdb\u5468\u671f\u306e\u6210\u9577\u671f\u3092\u5ef6\u9577<\/strong>\u3057\u3001\u4f11\u6b62\u671f\u304b\u3089\u6210\u9577\u671f\u3078\u306e\u79fb\u884c\u3092\u4fc3\u3059\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002\u305f\u3060\u30df\u30ce\u30ad\u30b7\u30b8\u30eb\u3084\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u306e\u3088\u3046\u306a\u5f37\u3044\u4f5c\u7528\u3067\u306f\u306a\u304f\u3001\u8efd\u5ea6\u306e\u30b1\u30fc\u30b9\u3084\u88dc\u52a9\u7684\u5f79\u5272\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u5b9f\u969b\u306e\u3068\u3053\u308d\u3001\u629c\u3051\u6bdb\u306e\u539f\u56e0\u304c\u8840\u884c\u4e0d\u826f\u3084\u6804\u990a\u4e0d\u826f\u306b\u3042\u308b\u5834\u5408\u306f\u80b2\u6bdb\u30c8\u30cb\u30c3\u30af\u3067\u6539\u5584\u304c\u898b\u3089\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u304c\u3001AGA\uff08\u7537\u6027\u30db\u30eb\u30e2\u30f3\u8981\u56e0\uff09\u3067\u306f\u9650\u5b9a\u7684\u3067\u3059\u3002\u4e00\u65b9\u3067\u3001<strong>\u30ab\u30d5\u30a7\u30a4\u30f3<\/strong>\u306a\u3069OTC\u30ec\u30d9\u30eb\u3067\u3082\u6ce8\u76ee\u3055\u308c\u308b\u6210\u5206\u304c\u3042\u308a\u307e\u3059\u3002\u30ab\u30d5\u30a7\u30a4\u30f3\u306f\u6bdb\u5305\u306b\u5c40\u6240\u9069\u7528\u3059\u308b\u3068\u3001\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u306b\u3088\u308b\u767a\u6bdb\u963b\u5bb3\u3092\u7de9\u548c\u3057\u3001\u6bdb\u5e79\u9577\u3092\u5ef6\u9577\u3059\u308bin vitro\u7d50\u679c\u304c\u3042\u308a\u307e\u3059\u3002\u307e\u305f\u5973\u6027\u578b\u8131\u6bdb\u75c7\u3067\u306e\u81e8\u5e8a\u8a66\u9a13\u3067\u306f0.2%\u30ab\u30d5\u30a7\u30a4\u30f3\u6eb6\u6db2\u304c\u30df\u30ce\u30ad\u30b7\u30b8\u30eb\u6eb6\u6db2\u3068\u9aea\u5bc6\u5ea6\u5897\u52a0\u52b9\u679c\u304c\u540c\u7b49\u3067\u3042\u3063\u305f\u3068\u306e\u5831\u544a\u3082\u3042\u308a\u307e\u3059<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9669136\/#:~:text=Ketoconazole%20shampoo%3A%20effect%20of%20long,The%20sebum%20casual%20level\" target=\"_blank\" rel=\"noreferrer noopener\">pubmed.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9669136\/#:~:text=Results%3A%20Hair%20density%20and%20size,The%20sebum%20casual%20level\" target=\"_blank\" rel=\"noreferrer noopener\">pubmed.ncbi.nlm.nih.gov<\/a>\u3002\u4f5c\u7528\u6a5f\u5e8f\u306f\u6bdb\u4e73\u982d\u7d30\u80de\u3067\u306eDHT\u5f71\u97ff\u6291\u5236\u3084cAMP\u4e0a\u6607\u306b\u3088\u308b\u7d30\u80de\u6d3b\u6027\u5316\u3068\u63a8\u6e2c\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u30b1\u30c8\u30b3\u30ca\u30be\u30fc\u30eb\u30b7\u30e3\u30f3\u30d7\u30fc\u306b\u3064\u3044\u3066\u3082\u5148\u8ff0\u306e\u901a\u308a<strong>\u6297\u708e\u75c7\u30fb\u6297\u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\u4f5c\u7528\u306b\u3088\u308b\u80b2\u6bdb\u52b9\u679c<\/strong>\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9669136\/#:~:text=Results%3A%20%20Hair%20density%20and,to%20be%20decreased%20by%20KCZ\" target=\"_blank\" rel=\"noreferrer noopener\">pubmed.ncbi.nlm.nih.gov<\/a>\u3002\u307e\u305f\u30ad\u30e3\u30d4\u30ad\u30b7\u30eb\u7b49\u306e\u65b0\u898f\u30da\u30d7\u30c1\u30c9\u306f\u3001Wnt\/\u03b2\u30ab\u30c6\u30cb\u30f3\u7d4c\u8def\u523a\u6fc0\u306b\u3088\u308a\u6bdb\u6bcd\u7d30\u80de\u5897\u6b96\u3092\u4fc3\u3059\u53ef\u80fd\u6027\u304c\u52d5\u7269\u5b9f\u9a13\u3067\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4ee5\u4e0a\u3088\u308a\u3001\u80b2\u6bdb\u5316\u7ca7\u54c1\u306e\u4f5c\u7528\u6a5f\u5e8f\u306f\u591a\u9762\u7684\u3067\u3059\u304c\u3001\u3044\u305a\u308c\u3082\u533b\u85ac\u54c1\u306b\u6bd4\u3079\u30de\u30a4\u30eb\u30c9\u3067\u3042\u308a\u3001<strong>\u9aea\u306e\u5065\u5eb7\u7dad\u6301<\/strong>\u3092\u88dc\u52a9\u3059\u308b\u5f79\u5272\u3067\u3059\u3002<\/p>\n\n\n\n<p><strong>\u30d5\u30b1\u30fb\u8102\u6f0f\u5bfe\u7b56:<\/strong> 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class=\"wp-block-heading\">\u81e8\u5e8a\u7684\u6709\u7528\u6027\u3068\u30a8\u30d3\u30c7\u30f3\u30b9<\/h3>\n\n\n\n<p><strong>\u6bdb\u9aea\u30c0\u30e1\u30fc\u30b8\u30b1\u30a2:<\/strong> 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noopener\">pubmed.ncbi.nlm.nih.gov<\/a>\u3002\u3053\u306e\u7d50\u679c\u306f\u9a5a\u304d\u3092\u3082\u3063\u3066\u53d7\u3051\u53d6\u3089\u308c\u307e\u3057\u305f\u304c\u3001\u8457\u8005\u3089\u306f\u300c\u30de\u30e9\u30bb\u30c1\u30a2\u6291\u5236\u3068\u6297\u708e\u75c7\u306b\u3088\u308a\u708e\u75c7\u6027\u8131\u6bdb\u6210\u5206\u304c\u6e1b\u5c11\u3057\u305f\u53ef\u80fd\u6027\u300d\u3092\u8ff0\u3079\u3066\u304a\u308a<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9669136\/#:~:text=Results%3A%20%20Hair%20density%20and,to%20be%20decreased%20by%20KCZ\" target=\"_blank\" rel=\"noreferrer noopener\">pubmed.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9669136\/#:~:text=appeared%20to%20be%20decreased%20by,KCZ\" target=\"_blank\" rel=\"noreferrer noopener\">pubmed.ncbi.nlm.nih.gov<\/a>\u3001AGA\u306b\u4ed8\u968f\u3059\u308b\u708e\u75c7\u3084\u8102\u6f0f\u72b6\u614b\u306e\u662f\u6b63\u304c\u6bdb\u5468\u671f\u306b\u597d\u5f71\u97ff\u3092\u4e0e\u3048\u305f\u3068\u63a8\u6e2c\u3057\u3066\u3044\u307e\u3059\u3002\u3055\u3089\u306b\u3001\u5c0f\u898f\u6a21\u306a\u304c\u3089<strong>\u30ab\u30d5\u30a7\u30a4\u30f3\u6eb6\u6db2<\/strong>\u306e\u81e8\u5e8a\u8a66\u9a13\u3067\u306f\u3001\u5973\u6027\u306b1\u65e52\u56de\u306e\u30ab\u30d5\u30a7\u30a4\u30f3\u982d\u76ae\u5857\u5e03\u30676\u30f6\u6708\u5f8c\u306b\u9aea\u306e\u6210\u9577\u7387\u304c\u30d7\u30e9\u30bb\u30dc\u3088\u308a\u826f\u597d\u3060\u3063\u305f\u3068\u306e\u5831\u544a\u304c\u3042\u308a\u307e\u3059\u3002\u6700\u8fd1\u306e\u30e1\u30bf\u89e3\u6790\u3067\u306f\u3001\u30df\u30ce\u30ad\u30b7\u30b8\u30eb\u3084\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u3092\u9664\u304f\u4ee3\u66ff\u7642\u6cd5\u3068\u3057\u3066\u3001\u4f4e\u8a3c\u62e0\u306a\u304c\u3089\u30ab\u30d5\u30a7\u30a4\u30f3\u30fb\u4e9c\u925b\u30fb\u30b1\u30c8\u30b3\u30ca\u30be\u30fc\u30eb\u30fb\u30d3\u30aa\u30c1\u30f3\u306a\u3069\u304c\u80af\u5b9a\u7684\u7d50\u679c\u3092\u793a\u3057\u305f\u3068\u307e\u3068\u3081\u3066\u3044\u307e\u3059\u3002\u305f\u3060\u3044\u305a\u308c\u3082\u5927\u898f\u6a21RCT\u304c\u4e0d\u8db3\u3057\u3066\u304a\u308a\u3001\u63a8\u5968\u5ea6\u3068\u3057\u3066\u306f\u88dc\u5b8c\u7642\u6cd5\u306e\u57df\u3092\u51fa\u307e\u305b\u3093\u3002\u3057\u305f\u304c\u3063\u3066\u81e8\u5e8a\u3067\u306f\u3001<strong>\u6a19\u6e96\u6cbb\u7642\u306b\u52a0\u3048\u3066<\/strong>\u982d\u76ae\u30b1\u30a2\u88fd\u54c1\u3092\u4f75\u7528\u3057\u3001\u7dcf\u5408\u7684\u306b\u30b3\u30f3\u30c7\u30a3\u30b7\u30e7\u30f3\u3092\u6574\u3048\u308b\u30a2\u30d7\u30ed\u30fc\u30c1\u304c\u73fe\u5b9f\u7684\u3067\u3059\u3002\u4f8b\u3048\u3070\u3001\u30df\u30ce\u30ad\u30b7\u30b8\u30eb\u5916\u7528\u60a3\u8005\u306b\u30d5\u30b1\u5bfe\u7b56\u3068\u3057\u3066\u30b1\u30c8\u30b3\u30ca\u30be\u30fc\u30eb\u30b7\u30e3\u30f3\u30d7\u30fc\u3092\u4f75\u7528\u3055\u305b\u305f\u7d50\u679c\u3001\u75d2\u307f\u3084\u30d5\u30b1\u304c\u6e1b\u308a\u6cbb\u7642\u7d99\u7d9a\u7387\u304c\u4e0a\u304c\u3063\u305f\u3068\u3044\u3046\u30b1\u30fc\u30b9\u3082\u3042\u308a\u307e\u3059\u3002\u80b2\u6bdb\u30b7\u30e3\u30f3\u30d7\u30fc\u81ea\u4f53\u306e\u52b9\u679c\u3067\u306f\u306a\u304f\u3068\u3082\u3001<strong>\u982d\u76ae\u74b0\u5883\u3092\u6574\u3048\u308b\u3053\u3068\u304c\u6cbb\u7642\u52b9\u679c\u6700\u5927\u5316\u306b\u3064\u306a\u304c\u308b<\/strong>\u3068\u3044\u3046\u70b9\u3067\u610f\u7fa9\u306f\u5927\u304d\u3044\u3067\u3059\u3002<\/p>\n\n\n\n<p><strong>\u30d5\u30b1\u30fb\u76ae\u819a\u708e\u306e\u5236\u5fa1:<\/strong> 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href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9669136\/#:~:text=Results%3A%20%20Hair%20density%20and,to%20be%20decreased%20by%20KCZ\" target=\"_blank\" rel=\"noreferrer noopener\">pubmed.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9669136\/#:~:text=appeared%20to%20be%20decreased%20by,KCZ\" target=\"_blank\" rel=\"noreferrer noopener\">pubmed.ncbi.nlm.nih.gov<\/a>\u3002ZPT\u3082\u9577\u671f\u4f7f\u7528\u8a66\u9a13\u3067\u8010\u6027\u7b49\u306a\u304f\u52b9\u679c\u6301\u7d9a\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u30b0\u30ea\u30c1\u30eb\u30ea\u30c1\u30f3\u9178\u914d\u5408\u30b7\u30e3\u30f3\u30d7\u30fc\u306e\u6297\u708e\u75c7\u52b9\u679c\u3082\u3001\u8efd\u5ea6\u306e\u982d\u76ae\u6e7f\u75b9\u306b\u6709\u7528\u3068\u306e\u5831\u544a\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u3089\u3088\u308a\u3001<strong>\u9069\u5207\u306a\u30b7\u30e3\u30f3\u30d7\u30fc\u9078\u629e\u306f\u982d\u76ae\u708e\u75c7\u306e\u7ba1\u7406\u306b\u5bc4\u4e0e<\/strong>\u3059\u308b\u3068\u3044\u3048\u307e\u3059\u3002\u76ae\u819a\u79d1\u3067\u306f\u30b9\u30c6\u30ed\u30a4\u30c9\u30ed\u30fc\u30b7\u30e7\u30f3\u3084\u5185\u670d\u6297\u771f\u83cc\u85ac\u3092\u4f7f\u3046\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u304c\u3001\u305d\u308c\u3089\u306e\u52b9\u679c\u3092\u65e5\u5e38\u30b1\u30a2\u3067\u88dc\u5b8c\u3059\u308b\u610f\u5473\u3067\u30d8\u30a2\u30b1\u30a2\u88fd\u54c1\u306e\u6d3b\u7528\u306f\u63a8\u5968\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u9664\u6bdb\u306e\u6d3b\u7528:<\/strong> 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href=\"https:\/\/link.springer.com\/article\/10.1208\/s12249-024-02943-2#:~:text=Efficacy%20of%20slimming%20cream%20containing,clinical%20study%20and%20literature\" target=\"_blank\" rel=\"noreferrer noopener\">link.springer.com<\/a><a href=\"https:\/\/www.mdpi.com\/2079-9284\/12\/4\/155#:~:text=Hexsel%20et%20al.%20,with%20genistein%20or%20Centella%20asiatica\" target=\"_blank\" rel=\"noreferrer noopener\">mdpi.com<\/a>\u3002L-\u30ab\u30eb\u30cb\u30c1\u30f3\u306f\u8102\u80aa\u306e\u71c3\u713c\u3092\u52a9\u3051\u308b\u88dc\u9175\u7d20\u3068\u3057\u3066\u914d\u5408\u3055\u308c\u307e\u3059\u3002\u30ec\u30c1\u30ce\u30fc\u30eb\u306f\u771f\u76ae\u3067\u30b3\u30e9\u30fc\u30b2\u30f3\u7523\u751f\u3092\u4fc3\u3057\u3001\u76ae\u819a\u306e\u30cf\u30ea\u3092\u9ad8\u3081\u51f8\u51f9\u3092\u76ee\u7acb\u3061\u306b\u304f\u304f\u3059\u308b\u72d9\u3044\u3067\u3059<a href=\"https:\/\/jcadonline.com\/study-depigmenting-agents-skin-color\/#:~:text=Arbutin%2C%20%28hydroquinone,be%20safe%20in%20cosmetic%20products\" target=\"_blank\" rel=\"noreferrer noopener\">jcadonline.com<\/a><a href=\"https:\/\/jcadonline.com\/study-depigmenting-agents-skin-color\/#:~:text=by%20a%20tyrosinase,provided%20that%20the%20contamination%20of\" target=\"_blank\" rel=\"noreferrer noopener\">jcadonline.com<\/a>\u3002\u30da\u30d7\u30c1\u30c9\u3068\u3057\u3066\u306f\u30d1\u30eb\u30df\u30c8\u30a4\u30eb\u30da\u30f3\u30bf\u30da\u30d7\u30c1\u30c9\u306a\u3069\u304c\u30b3\u30e9\u30fc\u30b2\u30f3\u5408\u6210\u4fc3\u9032\u3092\u8b33\u3063\u3066\u4f7f\u308f\u308c\u307e\u3059\u3002\u305d\u306e\u4ed6\u3001\u5357\u7c73\u7531\u6765\u306e<strong>\u30d6\u30e9\u30b8\u30eb\u30ac\u30e9\u30ca<\/strong>\uff08\u30ab\u30d5\u30a7\u30a4\u30f3\u8c4a\u5bcc\uff09\u3001<strong>\u30a4\u30c1\u30e7\u30a6<\/strong>\uff08\u5faa\u74b0\u6539\u5584\uff09\u3001<strong>\u30d6\u30c3\u30c1\u30e3\u30fc\u30ba\u30d6\u30eb\u30fc\u30e0<\/strong>\uff08\u9f20\u5f84\u90e8\u306e\u30ea\u30f3\u30d1\u5faa\u74b0\u6539\u5584\uff09\u306a\u3069\u306e\u690d\u7269\u30a8\u30ad\u30b9\u3082\u542b\u307e\u308c\u307e\u3059\u3002\u30bb\u30eb\u30e9\u30a4\u30c8\u30af\u30ea\u30fc\u30e0\u306f\u5857\u5e03\u6642\u306e<strong>\u30de\u30c3\u30b5\u30fc\u30b8<\/strong>\u304c\u63a8\u5968\u3055\u308c\u3001\u30de\u30c3\u30b5\u30fc\u30b8\u306b\u3088\u308b\u4e00\u6642\u7684\u5faa\u74b0\u6539\u5584\u52b9\u679c\u3082\u7d71\u5408\u3057\u3066\u4f5c\u7528\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u89d2\u5316\u75c7\u5bfe\u7b56\u88fd\u54c1:<\/strong> 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href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5849435\/#:~:text=Keratolytic%20agents%20such%20as%20salicylic,further%20aggravation%20of%20contact%20dermatitis\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5849435\/#:~:text=reduced%20trans,further%20aggravation%20of%20contact%20dermatitis\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002\u5c3f\u7d20\u914d\u5408\u30af\u30ea\u30fc\u30e0\u306e\u4e8c\u91cd\u76f2\u691c\u8a66\u9a13\u3067\u306f\u3001\u9b5a\u9c57\u766c\u60a3\u8005\u306e\u76ae\u819a\u6c34\u5206\u91cf\u4e0a\u6607\u3068\u523a\u6fc0\u306b\u5bfe\u3059\u308b\u62b5\u6297\u6027\u5411\u4e0a\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5849435\/#:~:text=Keratolytic%20agents%20such%20as%20salicylic,further%20aggravation%20of%20contact%20dermatitis\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002\u3053\u306e\u3088\u3046\u306b\u3001\u4fdd\u6e7f\u5264\u306e<strong>\u81e8\u5e8a\u52b9\u679c\u306f\u9ad8\u304f\u30a8\u30d3\u30c7\u30f3\u30b9\u3082\u5145\u5b9f<\/strong>\u3057\u3066\u3044\u307e\u3059\u3002\u30dc\u30c7\u30a3\u4fdd\u6e7f\u306b\u3088\u3063\u3066\u51ac\u306e\u4e7e\u71e5\u304b\u3086\u307f\uff08\u51ac\u5b63\u76ae\u819a\u305d\u3046\u75d2\u75c7\uff09\u304c\u8efd\u6e1b\u3057\u305f\u308a\u3001\u89d2\u5316\u75c7\u72b6\u304c\u6539\u5584\u3059\u308b\u3053\u3068\u306f\u65e5\u5e38\u8a3a\u7642\u3067\u5b9f\u611f\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u30bb\u30eb\u30e9\u30a4\u30c8\u30b1\u30a2:<\/strong> 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href=\"https:\/\/link.springer.com\/article\/10.1208\/s12249-024-02943-2#:~:text=Efficacy%20of%20slimming%20cream%20containing,clinical%20study%20and%20literature\" target=\"_blank\" rel=\"noreferrer noopener\">link.springer.com<\/a><a href=\"https:\/\/www.mdpi.com\/2079-9284\/12\/4\/155#:~:text=Hexsel%20et%20al.%20,with%20genistein%20or%20Centella%20asiatica\" target=\"_blank\" rel=\"noreferrer noopener\">mdpi.com<\/a>\u3002\u307e\u305f\u30ab\u30d5\u30a7\u30a4\u30f3\u306f\u8840\u7ba1\u53ce\u7e2e\u4f5c\u7528\u3067\u30ea\u30f3\u30d1\u6db2\u8caf\u7559\u3092\u6e1b\u3089\u3057\u3001\u4e00\u6642\u7684\u306b\u60a3\u90e8\u306e\u3080\u304f\u307f\u3092\u53d6\u308b\u50cd\u304d\u3082\u3042\u308a\u307e\u3059<a href=\"https:\/\/link.springer.com\/article\/10.1208\/s12249-024-02943-2#:~:text=Efficacy%20of%20slimming%20cream%20containing,clinical%20study%20and%20literature\" target=\"_blank\" rel=\"noreferrer noopener\">link.springer.com<\/a><a href=\"https:\/\/www.mdpi.com\/2079-9284\/12\/4\/155#:~:text=Hexsel%20et%20al.%20,with%20genistein%20or%20Centella%20asiatica\" target=\"_blank\" rel=\"noreferrer noopener\">mdpi.com<\/a>\u3002\u30ec\u30c1\u30ce\u30fc\u30eb\u306f\u8868\u76ae\u80a5\u539a\u3068\u771f\u76ae\u30b3\u30e9\u30fc\u30b2\u30f3\u5897\u751f\u3092\u4fc3\u3057\u3001\u30bb\u30eb\u30e9\u30a4\u30c8\u90e8\u306e\u76ae\u819a\u304c\u539a\u304f\u5f35\u308a\u3092\u5897\u3059\u3053\u3068\u3067\u51f8\u51f9\u3092\u76ee\u7acb\u3061\u306b\u304f\u304f\u3057\u307e\u3059\u3002\u5b9f\u969b\u30010.3%\u30ec\u30c1\u30ce\u30fc\u30eb\u30af\u30ea\u30fc\u30e0\u30926\u304b\u6708\u9593\u592a\u817f\u306b\u5857\u5e03\u3057\u305f\u8a66\u9a13\u3067\u306f\u3001\u76ae\u819a\u306e\u51f9\u51f8\u304c\u30d7\u30e9\u30bb\u30dc\u7fa4\u3088\u308a\u6539\u5584\u3057\u305f\u3068\u306e\u5831\u544a\u304c\u3042\u308a\u307e\u3059\u3002\u30da\u30d7\u30c1\u30c9\u306f\u30b3\u30e9\u30fc\u30b2\u30f3\u3084\u30a8\u30e9\u30b9\u30c1\u30f3\u7523\u751f\u3092\u5897\u3084\u3057\u3001\u76ae\u819a\u306e\u652f\u6301\u7d44\u7e54\u3092\u5f37\u5316\u3057\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u4f5c\u7528\u3092\u6301\u3064\u6210\u5206\u3092\u914d\u5408\u3057\u305f\u30bb\u30eb\u30e9\u30a4\u30c8\u30af\u30ea\u30fc\u30e0\u30921\u65e52\u56de\u30de\u30c3\u30b5\u30fc\u30b8\u5857\u5e03\u3059\u308b\u3053\u3068\u3067\u3001<strong>\u30bb\u30eb\u30e9\u30a4\u30c8\u306e\u5916\u89b3\u304c\u8efd\u6e1b<\/strong>\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u81e8\u5e8a\u8a66\u9a13\u3067\u306f\u3001\u30ab\u30d5\u30a7\u30a4\u30f3\u30fb\u30ec\u30c1\u30ce\u30fc\u30eb\u542b\u6709\u30b8\u30a7\u30eb8\u9031\u9593\u5857\u5e03\u306b\u3088\u308a\u3001\u592a\u817f\u5468\u56f2\u5f84\u304c\u5e73\u57472cm\u6e1b\u5c11\u3057\u3001\u76ae\u819a\u8868\u9762\u51f9\u51f8\u304c\u753b\u50cf\u89e3\u6790\u3067\u9855\u8457\u306b\u6539\u5584\u3057\u305f\u3068\u306e\u7d50\u679c\u304c\u3042\u308a\u307e\u3059<a href=\"https:\/\/www.jaad.org\/article\/S0190-9622(14)00090-5\/fulltext#:~:text=Twice%20daily%20application%20of%20a,with%20maximum%20of%2072.12\" target=\"_blank\" rel=\"noreferrer noopener\">jaad.org<\/a><a href=\"https:\/\/www.mdpi.com\/2079-9284\/12\/4\/155#:~:text=eight%20weeks%20to%20the%20thighs,when%20used%20in%20conjunction%20with\" target=\"_blank\" rel=\"noreferrer noopener\">mdpi.com<\/a>\u3002\u305f\u3060\u3057\u30bb\u30eb\u30e9\u30a4\u30c8\u6539\u5584\u30a8\u30d3\u30c7\u30f3\u30b9\u306f\u30e1\u30fc\u30ab\u30fc\u4e3b\u5c0e\u306e\u7814\u7a76\u304c\u591a\u304f\u3001\u30d7\u30e9\u30bb\u30dc\u5bfe\u7167\u3084\u9577\u671f\u52b9\u679c\u306b\u3064\u3044\u3066\u8b70\u8ad6\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u308c\u3067\u3082\u30de\u30c3\u30b5\u30fc\u30b8\u306e\u4f75\u7528\u306f\u5faa\u74b0\u6539\u5584\u306b\u5bc4\u4e0e\u3057\u3001\u4e3b\u89b3\u7684\u306a\u6ed1\u3089\u304b\u3055\u5411\u4e0a\u306b\u3064\u306a\u304c\u308a\u3084\u3059\u3044\u305f\u3081\u3001\u591a\u304f\u306e\u88fd\u54c1\u304c**\u300c\u5857\u308a\u8fbc\u307f\u30de\u30c3\u30b5\u30fc\u30b8\u300d\u3092\u63a8\u5968<strong>\u3057\u3066\u3044\u307e\u3059\u3002\u307e\u3068\u3081\u308b\u3068\u3001\u30bb\u30eb\u30e9\u30a4\u30c8\u30b1\u30a2\u88fd\u54c1\u306f<\/strong>\u5373\u52b9\u6027\u306f\u306a\u304f\u52b9\u679c\u3082\u500b\u4eba\u5dee**\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u7d99\u7d9a\u3059\u308c\u3070\u51f8\u51f9\u306e\u5ea6\u5408\u3044\u3092\u8efd\u6e1b\u3057\u76ae\u819a\u306e\u898b\u305f\u76ee\u3092\u6539\u5584\u3059\u308b\u88dc\u52a9\u624b\u6bb5\u3068\u306a\u308a\u5f97\u307e\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3933246\/#:~:text=,for%20the\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/www.mdpi.com\/2079-9284\/12\/4\/155#:~:text=MDPI%20www.mdpi.com%20%20,6%E2%80%9312%20weeks%2C%20particularly%20when\" target=\"_blank\" rel=\"noreferrer noopener\">mdpi.com<\/a>\u3002<\/p>\n\n\n\n<p><strong>\u89d2\u5316\u75c7\u5bfe\u7b56:<\/strong> 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class=\"wp-block-heading\">\u6700\u8fd1\u306e\u7814\u7a76\u52d5\u5411<\/h3>\n\n\n\n<p><strong>\u30bb\u30eb\u30e9\u30a4\u30c8\u7814\u7a76\u306e\u6df1\u5316:<\/strong> \u30bb\u30eb\u30e9\u30a4\u30c8\u306b\u95a2\u3057\u3066\u306f\u8fd1\u5e74\u300c\u5fae\u5c0f\u5faa\u74b0\u969c\u5bb3\u3068\u7dda\u7dad\u5316\u300d\u304c\u6ce8\u76ee\u3055\u308c\u3001\u5358\u306b\u8102\u80aa\u6e1b\u5c11\u3060\u3051\u3067\u306a\u304f<strong>\u7dda\u7dad\u9694\u58c1\u306e\u786c\u5316\u3092\u6539\u5584<\/strong>\u3059\u308b\u8a66\u307f\u304c\u884c\u308f\u308c\u3066\u3044\u307e\u3059<a href=\"https:\/\/www.mdpi.com\/2079-9284\/12\/4\/155#:~:text=study%20evaluated%20the%20efficacy%20of,with%20visible%20results%20and%2091\" target=\"_blank\" rel=\"noreferrer noopener\">mdpi.com<\/a><a href=\"https:\/\/www.mdpi.com\/2079-9284\/12\/4\/155#:~:text=grading%2C%20and%20patient%20self,invasive%20option%20for%20the\" target=\"_blank\" rel=\"noreferrer noopener\">mdpi.com<\/a>\u3002\u4f8b\u3048\u3070\u30da\u30d7\u30c1\u30c0\u30fc\u30bc\u3084\u690d\u7269\u9175\u7d20\u3067\u9694\u58c1\u306e\u30b3\u30e9\u30fc\u30b2\u30f3\u67b6\u6a4b\u3092\u7de9\u3081\u308b\u3053\u3068\u3084\u3001\u8d85\u97f3\u6ce2\u30c7\u30d0\u30a4\u30b9\u3067\u5c40\u6240\u7684\u306b\u9694\u58c1\u3092\u7834\u65ad\u3059\u308b\u65b9\u6cd5\u304c\u6a21\u7d22\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4e00\u65b9\u3001\u30bb\u30eb\u30e9\u30a4\u30c8\u8a55\u4fa1\u30823D\u76ae\u819a\u8a08\u6e2c\u5668\u3067\u5ba2\u89b3\u5316\u304c\u9032\u307f\u3001\u30bb\u30eb\u30e9\u30a4\u30c8\u30b0\u30ec\u30fc\u30c9\u306e\u6a19\u6e96\u5316\uff08N\u00fcrnberger\u2013M\u00fcller\u30b9\u30b1\u30fc\u30eb\u306a\u3069\uff09\u304c\u56fd\u969b\u6bd4\u8f03\u53ef\u80fd\u306b\u306a\u3063\u3066\u304d\u307e\u3057\u305f<a href=\"https:\/\/www.mdpi.com\/2079-9284\/12\/4\/155#:~:text=Cellulite%20severity%20is%20typically%20assessed,II%20and%20III%20can%20be\" target=\"_blank\" rel=\"noreferrer noopener\">mdpi.com<\/a>\u3002\u3053\u308c\u306b\u3088\u308a\u65b0\u305f\u306a\u30af\u30ea\u30fc\u30e0\u3084\u65bd\u8853\u306e\u52b9\u679c\u3092\u3088\u308a\u6b63\u78ba\u306b\u691c\u8a3c\u3067\u304d\u3001\u5c06\u6765\u7684\u306b\u30bb\u30eb\u30e9\u30a4\u30c8\u6cbb\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u7b56\u5b9a\u3082\u8996\u91ce\u306b\u5165\u3063\u3066\u3044\u307e\u3059\u3002\u4eca\u306e\u3068\u3053\u308d\u5316\u7ca7\u54c1\u3067\u306f\u30012025\u5e74\u306e\u7814\u7a76\u3067\u30ab\u30d5\u30a7\u30a4\u30f3\u30fb\u30b2\u30cb\u30b9\u30c6\u30a4\u30f3\u542b\u6709\u30af\u30ea\u30fc\u30e0\u30928\u9031\u9593\u4f7f\u7528\u3057\u30013D\u8a08\u6e2c\u3067\u30bb\u30eb\u30e9\u30a4\u30c8\u306e\u304f\u307c\u307f\u4f53\u7a4d\u304c\u5e73\u574723.5%\u6e1b\u5c11\u3057\u305f\u3068\u306e\u30c7\u30fc\u30bf\u304c\u767a\u8868\u3055\u308c\u307e\u3057\u305f<a href=\"https:\/\/www.mdpi.com\/2079-9284\/12\/4\/155#:~:text=study%20evaluated%20the%20efficacy%20of,with%20visible%20results%20and%2091\" target=\"_blank\" rel=\"noreferrer noopener\">mdpi.com<\/a><a href=\"https:\/\/www.mdpi.com\/2079-9284\/12\/4\/155#:~:text=eight%20weeks%20to%20the%20thighs,These%20findings\" target=\"_blank\" rel=\"noreferrer noopener\">mdpi.com<\/a>\u3002\u3053\u308c\u306f\u30d7\u30e9\u30bb\u30dc\u5bfe\u7167\u3067\u306a\u3044\u3082\u306e\u306e\u6709\u671b\u306a\u7d50\u679c\u3067\u3042\u308a\u3001\u3053\u3046\u3057\u305f\u30a8\u30d3\u30c7\u30f3\u30b9\u304c\u84c4\u7a4d\u3059\u308c\u3070\u30bb\u30eb\u30e9\u30a4\u30c8\u30b1\u30a2\u5316\u7ca7\u54c1\u306e\u4f4d\u7f6e\u3065\u3051\u3082\u660e\u78ba\u306b\u306a\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<p><strong>\u80a5\u6e80\u30fb\u4ee3\u8b1d\u3068\u306e\u95a2\u9023:<\/strong> 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class=\"wp-block-heading\">6. \u7537\u6027\u7528\u5316\u7ca7\u54c1\uff08\u76ae\u8102\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3001\u30b7\u30a7\u30fc\u30d3\u30f3\u30b0\u5f8c\u30b1\u30a2\u3001\u8584\u6bdb\u30fb\u30cb\u30ad\u30d3\u5bfe\u7b56\u306a\u3069\uff09<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">\u7537\u6027\u76ae\u819a\u306e\u7279\u6027\u3068\u7537\u6027\u7528\u5316\u7ca7\u54c1\u306e\u7279\u5fb4<\/h3>\n\n\n\n<p><strong>\u7537\u6027\u76ae\u819a\u306e\u7279\u5fb4:<\/strong> 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<strong>\u76ae\u8102\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb<\/strong>\u76ee\u7684\u3067\u306f\u3001\u30ab\u30aa\u30ea\u30f3\u3084\u30b7\u30ea\u30ab\u306a\u3069\u306e\u5fae\u7c92\u5b50\u30d1\u30a6\u30c0\u30fc\u304c\u76ae\u8102\u3092\u5438\u7740\u3057\u30c6\u30ab\u30ea\u3092\u6291\u3048\u307e\u3059\u3002\u30d3\u30bf\u30df\u30f3B3\uff08\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9\uff09\u306f\u76ae\u8102\u5206\u6ccc\u6291\u5236\u52b9\u679c\u304c\u3042\u308a\u3001\u7537\u6027\u5316\u7ca7\u6c34\u306b\u3082\u914d\u5408\u3055\u308c\u307e\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=As%20an%20initial%20step%20based,with%20the%20categorization%20of%20quality\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=dermocosmetics%2C%20cosmeceutical%2C%20salicylic%20acid%2C%20lipohydroxyacid%2C,with%20the%20categorization%20of%20quality\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002\u307e\u305f\u4e9c\u925b\u5316\u5408\u7269\uff08\u30b0\u30eb\u30b3\u30f3\u9178\u4e9c\u925b\u306a\u3069\uff09\u306f5\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\u963b\u5bb3\u306b\u3088\u308b\u76ae\u8102\u4f4e\u6e1b\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<strong>\u30a2\u30d5\u30bf\u30fc\u30b7\u30a7\u30fc\u30d6<\/strong>\u3067\u306f\u3001\u6bba\u83cc\u4f5c\u7528\u3068\u53ce\u6582\u4f5c\u7528\u3092\u6301\u3064\u30a8\u30bf\u30ce\u30fc\u30eb\u3084\u30cf\u30de\u30e1\u30ea\u30b9\u6c34\u304c\u53e4\u5178\u7684\u306b\u4f7f\u308f\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u6700\u8fd1\u306f\u30a2\u30eb\u30b3\u30fc\u30eb\u30d5\u30ea\u30fc\u5fd7\u5411\u3082\u3042\u308a\u3001\u4ee3\u308f\u308a\u306b<strong>\u30a2\u30ed\u30a8\u30d9\u30e9<\/strong>\u3084<strong>\u30ab\u30e2\u30df\u30fc\u30eb\u30a8\u30ad\u30b9<\/strong>\uff08\u03b1-\u30d3\u30b5\u30dc\u30ed\u30fc\u30eb\uff09\u306a\u3069\u306e\u6297\u708e\u75c7\u6210\u5206\u3001<strong>\u30a2\u30e9\u30f3\u30c8\u30a4\u30f3<\/strong>\u3084\u30d1\u30f3\u30c6\u30ce\u30fc\u30eb\u3068\u3044\u3063\u305f\u7d44\u7e54\u4fee\u5fa9\u6210\u5206\u304c\u914d\u5408\u3055\u308c\u307e\u3059\u3002\u9aed\u5243\u308a\u8ca0\u3051\u4e88\u9632\u306b\u30b0\u30ea\u30c1\u30eb\u30ea\u30c1\u30f3\u9178\u3084\u30a4\u30bd\u30d7\u30ed\u30d4\u30eb\u30e1\u30c1\u30eb\u30d5\u30a7\u30ce\u30fc\u30eb\uff08\u6bba\u83cc\uff09\u304c\u542b\u307e\u308c\u308b\u88fd\u54c1\u3082\u591a\u3044\u3067\u3059\u3002<strong>\u30cb\u30ad\u30d3\u5bfe\u7b56<\/strong>\u3067\u306f\u3001\u30b5\u30ea\u30c1\u30eb\u9178\u3084\u30a4\u30aa\u30a6\u3001\u30ec\u30be\u30eb\u30b7\u30ce\u30fc\u30eb\u304c\u7537\u6027\u7528\u6d17\u9854\u6599\u30fb\u5316\u7ca7\u6c34\u306b\u914d\u5408\u3055\u308c\u3001\u6bdb\u7a74\u8a70\u307e\u308a\u9664\u53bb\u3068\u6bba\u83cc\u3092\u884c\u3044\u307e\u3059\u3002\u30c6\u30a3\u30fc\u30c4\u30ea\u30fc\u30aa\u30a4\u30eb\u3082\u81ea\u7136\u6d3e\u6297\u83cc\u6210\u5206\u3068\u3057\u3066\u4eba\u6c17\u3067\u3059\u3002<strong>\u8584\u6bdb\u5bfe\u7b56<\/strong>\u306e\u30c8\u30cb\u30c3\u30af\u306b\u3064\u3044\u3066\u306f\u524d\u8ff0\u306e\u80b2\u6bdb\u5264\u3068\u540c\u69d8\u3067\u3001\u30bb\u30f3\u30d6\u30ea\u30a8\u30ad\u30b9\u3084\u30d3\u30bf\u30df\u30f3E\u8a98\u5c0e\u4f53\u3001\u30e1\u30f3\u30c8\u30fc\u30eb\u306a\u3069\u304c\u5165\u308a\u307e\u3059\uff08\u7537\u6027\u5411\u3051\u306f\u6e05\u6dbc\u611f\u5f37\u3081\u306e\u5834\u5408\u304c\u591a\u3044\uff09\u3002\u3055\u3089\u306b\u7537\u6027\u3067\u306f<strong>\u4f53\u81ed<\/strong>\uff08\u52a0\u9f62\u81ed\uff09\u5bfe\u7b56\u3082\u91cd\u8996\u3055\u308c\u3001\u30b9\u30ad\u30f3\u30b1\u30a2\u306b\u3082\u30b7\u30af\u30ed\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\uff08\u81ed\u6c17\u5438\u7740\uff09\u3084\u30c1\u30e3\u4e7e\u7559\u6db2\uff08\u6297\u83cc\u6d88\u81ed\uff09\u306a\u3069\u304c\u914d\u5408\u3055\u308c\u305f\u3082\u306e\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u7537\u6027\u7528\u30e1\u30fc\u30af\u30a2\u30c3\u30d7:<\/strong> 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href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=As%20an%20initial%20step%20based,with%20the%20categorization%20of%20quality\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=dermocosmetics%2C%20cosmeceutical%2C%20salicylic%20acid%2C%20lipohydroxyacid%2C,with%20the%20categorization%20of%20quality\" target=\"_blank\" rel=\"noreferrer 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href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=This%20publication%20is%20based%20on,patients%20with%20very%20mild%20to\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=of%20dermatologists%20with%20interest%20and,patients%20with%20very%20mild%20to\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002<\/p>\n\n\n\n<p><strong>QOL\u3078\u306e\u5f71\u97ff:<\/strong> 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class=\"wp-block-heading\">7. \u30d5\u30ec\u30b0\u30e9\u30f3\u30b9\u5316\u7ca7\u54c1\uff08\u9999\u6599\u306e\u4f5c\u7528\u3001\u611f\u60c5\u30fb\u751f\u7406\u3078\u306e\u5f71\u97ff\u3001\u5b89\u5168\u6027\uff09<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">\u9999\u6599\u3068\u30d5\u30ec\u30b0\u30e9\u30f3\u30b9\u5316\u7ca7\u54c1\u306e\u6982\u8981<\/h3>\n\n\n\n<p><strong>\u30d5\u30ec\u30b0\u30e9\u30f3\u30b9\u5316\u7ca7\u54c1\u306e\u7a2e\u985e:<\/strong> 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noopener\">sciencedirect.com<\/a>\u3002\u4f8b\u3048\u3070\u30e9\u30d9\u30f3\u30c0\u30fc\u306e\u4e3b\u8981\u6210\u5206\u30ea\u30ca\u30ed\u30fc\u30eb\u306f\u55c5\u899a\u304b\u3089\u6241\u6843\u4f53\u3078\u4f5c\u7528\u3057\u3001\u30b9\u30c8\u30ec\u30b9\u5fdc\u7b54\u3092\u548c\u3089\u3052\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0965229922000346#:~:text=The%20effect%20of%20lavender%20on,In%20recent%20years%2C%20many\" target=\"_blank\" rel=\"noreferrer noopener\">sciencedirect.com<\/a>\u3002\u9999\u6599\u306e\u7cbe\u795e\u4f5c\u7528\u306f\u3001\u3053\u306e\u55c5\u899a\u304b\u3089\u306e\u795e\u7d4c\u7d4c\u8def\u306b\u3088\u308b\u3082\u306e\u304c\u5927\u304d\u3044\u3067\u3059\u3002\u307e\u305f\u4e00\u90e8\u306e\u9999\u6c17\u6210\u5206\u306f\u76ae\u819a\u304b\u3089\u5438\u53ce\u3055\u308c\u8840\u6d41\u3092\u901a\u3058\u3066\u4e2d\u67a2\u306b\u4f5c\u7528\u3059\u308b\u53ef\u80fd\u6027\u3082\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u4e3b\u7d4c\u8def\u306f\u55c5\u899a\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u9999\u6599\u306e\u52b9\u679c\u306f\u7a2e\u985e\u306b\u3088\u308a\u7570\u306a\u308a\u3001\u30b7\u30c8\u30e9\u30b9\u7cfb\u3084\u30da\u30d1\u30fc\u30df\u30f3\u30c8\u306a\u3069\u306f\u899a\u9192\u30fb\u96c6\u4e2d\u3092\u4fc3\u3057\u3001\u30e9\u30d9\u30f3\u30c0\u30fc\u3084\u30ab\u30e2\u30df\u30fc\u30eb\u306f\u93ae\u9759\u30fb\u7761\u7720\u8a98\u5c0e\u306b\u52b9\u679c\u304c\u3042\u308b\u3068\u306e\u7814\u7a76\u304c\u591a\u3044\u3067\u3059<a href=\"https:\/\/www.asian-nursingresearch.com\/article\/S1976-1317%2821%2900077-3\/fulltext#:~:text=...%20www.asian,administration%20increased%20the%20anxiolytic%20effects\" target=\"_blank\" rel=\"noreferrer noopener\">asian-nursingresearch.com<\/a><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0965229922000346#:~:text=The%20effect%20of%20lavender%20on,In%20recent%20years%2C%20many\" target=\"_blank\" rel=\"noreferrer noopener\">sciencedirect.com<\/a>\u3002\u3053\u308c\u306f\u9999\u308a\u5206\u5b50\u304c\u7570\u306a\u308b\u8133\u5185\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u7cfb\u306b\u5f71\u97ff\u3059\u308b\u305f\u3081\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u611f\u60c5\u30fb\u751f\u7406\u3078\u306e\u5f71\u97ff:<\/strong> \u9999\u308a\u306f<strong>\u5fc3\u7406\u7684\u52b9\u679c<\/strong>\uff08\u30ea\u30e9\u30c3\u30af\u30b9\u3084\u8208\u596e\uff09\u3060\u3051\u3067\u306a\u304f\u3001\u751f\u7406\u6a5f\u80fd\u306b\u3082\u5f71\u97ff\u3092\u53ca\u307c\u3059\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u30e9\u30d9\u30f3\u30c0\u30fc\u30a2\u30ed\u30de\u3092\u5438\u5165\u3057\u305f\u88ab\u9a13\u8005\u306f\u8108\u62cd\u3084\u8840\u5727\u304c\u4f4e\u4e0b\u3057\u3001\u8133\u6ce2\u3067\u306f\u03b1\u6ce2\u5897\u52a0\uff08\u30ea\u30e9\u30c3\u30af\u30b9\u72b6\u614b\uff09\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0965229922000346#:~:text=Lavender%20essential%20oil%20may%20reduce,In%20recent%20years%2C%20many\" target=\"_blank\" rel=\"noreferrer noopener\">sciencedirect.com<\/a>\u3002\u30da\u30d1\u30fc\u30df\u30f3\u30c8\u306e\u9999\u308a\u306f\u904b\u52d5\u6642\u306e\u75b2\u52b4\u611f\u8efd\u6e1b\u3084\u547c\u5438\u6570\u5897\u52a0\u3092\u3082\u305f\u3089\u3057\u3001\u899a\u9192\u52b9\u679c\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u30ec\u30e2\u30f3\u306e\u9999\u308a\u306f\u4ea4\u611f\u795e\u7d4c\u3092\u523a\u6fc0\u3057\u4f5c\u696d\u52b9\u7387\u3092\u9ad8\u3081\u305f\u3068\u3044\u3046\u5831\u544a\u3082\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u3089\u306f<strong>\u30a2\u30ed\u30de\u30c6\u30e9\u30d4\u30fc<\/strong>\u3068\u3057\u3066\u53e4\u304f\u304b\u3089\u7d4c\u9a13\u7684\u306b\u8a00\u308f\u308c\u3066\u304d\u305f\u52b9\u679c\u304c\u3001\u79d1\u5b66\u7684\u306b\u3082\u88cf\u4ed8\u3051\u3089\u308c\u3064\u3064\u3042\u308b\u3082\u306e\u3067\u3059\u3002\u9999\u308a\u3068\u8a18\u61b6\u306e\u7d50\u3073\u3064\u304d\u3082\u5f37\u529b\u3067\u3001\u7279\u5b9a\u306e\u5302\u3044\u304c\u904e\u53bb\u306e\u8a18\u61b6\u3084\u611f\u60c5\u3092\u9bae\u660e\u306b\u547c\u3073\u8d77\u3053\u3059\uff08\u30d7\u30eb\u30fc\u30b9\u30c8\u52b9\u679c\uff09\u3053\u3068\u306f\u65e5\u5e38\u7684\u306b\u7d4c\u9a13\u3055\u308c\u307e\u3059\u3002\u55c5\u899a\u306f\u6d77\u99ac\uff08\u8a18\u61b6\u5f62\u6210\uff09\u3068\u6241\u6843\u4f53\uff08\u611f\u60c5\u51e6\u7406\uff09\u306b\u76f4\u63a5\u5165\u529b\u3059\u308b\u305f\u3081\u3001\u4ed6\u611f\u899a\u3088\u308a\u60c5\u52d5\u3068\u6df1\u304f\u7d50\u3073\u3064\u304f\u305f\u3081\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u9999\u308a\u3092\u4e0a\u624b\u304f\u4f7f\u3048\u3070\u3001\u7dca\u5f35\u3092\u307b\u3050\u3057\u305f\u308a\u6c17\u5206\u3092\u9ad8\u63da\u3055\u305b\u305f\u308a\u3067\u304d\u308b\u308f\u3051\u3067\u3059\u3002\u4f8b\u3048\u3070\u533b\u7642\u73fe\u5834\u3067\u3001\u60a3\u8005\u306e\u4e0d\u5b89\u8efd\u6e1b\u306b\u30e9\u30d9\u30f3\u30c0\u30fc\u9999\u3092\u711a\u304f\u8a66\u307f\u304c\u306a\u3055\u308c\u3001\u8853\u524d\u4e0d\u5b89\u304c\u6709\u610f\u306b\u6e1b\u3063\u305f\u3068\u3044\u3046\u7814\u7a76\u304c\u3042\u308a\u307e\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6007527\/#:~:text=time%3F%20pmc,supported%20by%20clinical%20efficacy%20studies\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/bmccomplementmedtherapies.biomedcentral.com\/articles\/10.1186\/s12906-023-04231-1#:~:text=The%20effect%20of%20lavender%20aroma,benzodiazepine%20use%20for%20anxiety%20disorders\" target=\"_blank\" rel=\"noreferrer noopener\">bmccomplementmedtherapies.biomedcentral.com<\/a>\u3002\u3055\u3089\u306b\u3001\u67d1\u6a58\u7cfb\u306e\u9999\u308a\u306f\u4e00\u90e8\u306e\u3046\u3064\u75c5\u60a3\u8005\u306b\u6297\u3046\u3064\u52b9\u679c\u3092\u793a\u3057\u305f\u3068\u3044\u3046\u5831\u544a\u3082\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u77e5\u898b\u304b\u3089\u3001\u9999\u6599\u306f<strong>\u5fc3\u8eab\u306e\u5065\u5eb7\u306b\u5f71\u97ff\u3092\u6301\u3064<\/strong>\u5b9f\u8cea\u7684\u306a\u8981\u7d20\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u5b89\u5168\u6027:<\/strong> 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href=\"https:\/\/jcadonline.com\/study-depigmenting-agents-skin-color\/#:~:text=as%20listed%20in%20Annexure%20III,solar%20lentigines%20after%2012%20weeks%E2%80%99\" target=\"_blank\" rel=\"noreferrer noopener\">jcadonline.com<\/a><a href=\"https:\/\/jcadonline.com\/study-depigmenting-agents-skin-color\/#:~:text=as%20listed%20in%20Annexure%20III,solar%20lentigines%20after%2012%20weeks%E2%80%99\" target=\"_blank\" rel=\"noreferrer noopener\">jcadonline.com<\/a>\u3002\u307e\u305f\u5149\u6bd2\u6027\u3092\u6301\u3064\u9999\u6599\uff08\u30d9\u30eb\u30ac\u30e2\u30c3\u30c8\u30aa\u30a4\u30eb\u4e2d\u306e\u30d9\u30eb\u30ac\u30d7\u30c6\u30f3\u306a\u3069\uff09\u306f\u9664\u53bb\u3057\u3066\u4f7f\u7528\u3059\u308b\u306e\u304c\u5e38\u8b58\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u6b74\u53f2\u7684\u306b\u3001\u30aa\u30fc\u30af\u30e2\u30b9\u62bd\u51fa\u7269\u304c\u5f37\u529b\u30a2\u30ec\u30eb\u30b2\u30f3\u3068\u3057\u3066\u4f7f\u7528\u898f\u5236\u3055\u308c\u3001\u3053\u308c\u3092\u4ee3\u66ff\u3059\u308b\u5408\u6210\u30e0\u30b9\u30af\u306e\u4e00\u90e8\uff08\u30cb\u30c8\u30ed\u30e0\u30b9\u30af\uff09\u306f\u84c4\u7a4d\u6027\u30fb\u5185\u5206\u6ccc\u304b\u304f\u4e71\u7591\u60d1\u3067\u73fe\u5728\u307b\u3068\u3093\u3069\u4f7f\u308f\u308c\u307e\u305b\u3093<a href=\"https:\/\/jcadonline.com\/study-depigmenting-agents-skin-color\/#:~:text=Arbutin%2C%20%28hydroquinone,be%20safe%20in%20cosmetic%20products\" target=\"_blank\" rel=\"noreferrer noopener\">jcadonline.com<\/a><a href=\"https:\/\/jcadonline.com\/study-depigmenting-agents-skin-color\/#:~:text=as%20listed%20in%20Annexure%20III,solar%20lentigines%20after%2012%20weeks%E2%80%99\" target=\"_blank\" rel=\"noreferrer noopener\">jcadonline.com<\/a>\u3002\u5b89\u5168\u306a\u9999\u6599\u3068\u3057\u3066<strong>\u30db\u30ef\u30a4\u30c8\u30e0\u30b9\u30af\uff08\u591a\u74b0\u5f0f\u5408\u6210\u30e0\u30b9\u30af\uff09\u304c\u4f7f\u308f\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u3053\u308c\u3082\u74b0\u5883\u4e2d\u84c4\u7a4d\u304c\u61f8\u5ff5\u3055\u308c\u307e\u3059\u3002\u9999\u6599\u306f\u7d4c\u76ae\u5438\u53ce\u3088\u308a\u5438\u5165\u66b4\u9732\u304c\u4e3b\u4f53\u306a\u306e\u3067\u3001\u52b4\u50cd\u885b\u751f\u4e0a\u306f\u9999\u6599\u88fd\u9020\u5de5\u5834\u3067\u306e\u5598\u606f\u30ea\u30b9\u30af\u306a\u3069\u3082\u554f\u984c\u306b\u306a\u308a\u307e\u3059\u3002\u3057\u304b\u3057\u4e00\u822c\u6d88\u8cbb\u8005\u304c\u9069\u91cf\u4f7f\u7528\u3059\u308b\u7bc4\u56f2\u3067\u306f\u3001\u6025\u6027\u6bd2\u6027\u306f\u307b\u307c\u3042\u308a\u307e\u305b\u3093\u3002\u3080\u3057\u308d\u654f\u611f\u808c\u3067\u306f\u9999\u308a\u6210\u5206\u305d\u306e\u3082\u306e\u304c\u523a\u6fc0\u306b\u306a\u308a\u3046\u308b\u305f\u3081\u3001\u654f\u611f\u808c\u7528\u88fd\u54c1\u306f\u7121\u9999\u6599\u304c\u57fa\u672c\u3067\u3059\u3002\u6628\u4eca\u300c\u9999\u5bb3\u300d\u3068\u3044\u3046\u8a00\u8449\u304c\u51fa\u308b\u307b\u3069\u5f37\u3044\u9999\u308a\u306b\u3088\u308b\u4ed6\u8005\u3078\u306e\u5065\u5eb7\u88ab\u5bb3\uff08\u982d\u75db\u3084\u6c17\u5206\u4e0d\u826f\uff09\u3082\u793e\u4f1a\u554f\u984c\u5316\u3057\u3001\u9999\u6c34\u306eTPO\u304c\u8b70\u8ad6\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u5b89\u5168\u6027\u306b\u306f\u672c\u4eba\u306e\u76ae\u819a\u3078\u306e\u5b89\u5168<\/strong>\u3068<strong>\u5468\u56f2\u3078\u306e\u914d\u616e<\/strong>\u306e\u4e8c\u5074\u9762\u304c\u3042\u308a\u3001\u5f8c\u8005\u306f\u30de\u30ca\u30fc\u306e\u554f\u984c\u3068\u3057\u3066\u5553\u767a\u304c\u9032\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u611f\u60c5\u30fb\u751f\u7406\u3078\u306e\u5177\u4f53\u7684\u5f71\u97ff<\/h3>\n\n\n\n<p><strong>\u30ea\u30e9\u30c3\u30af\u30b9\u52b9\u679c:<\/strong> \u30e9\u30d9\u30f3\u30c0\u30fc\u7cbe\u6cb9\u306f\u6700\u3082\u7814\u7a76\u3055\u308c\u305f\u9999\u6599\u306e\u4e00\u3064\u3067\u3001\u591a\u304f\u306eRCT\u3084\u30e1\u30bf\u89e3\u6790\u304c\u3042\u308a\u307e\u3059<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31655395\/#:~:text=Effects%20of%20lavender%20on%20anxiety%3A,is%20only%20an%20indication\" target=\"_blank\" rel=\"noreferrer noopener\">pubmed.ncbi.nlm.nih.gov<\/a>\u3002\u7d4c\u53e3\u6442\u53d6\uff08\u30ab\u30d7\u30bb\u30eb\uff09\u3067\u4e0d\u5b89\u969c\u5bb3\u6539\u5584\u30a8\u30d3\u30c7\u30f3\u30b9\u304c\u5f37\u3044\u3067\u3059\u304c\u3001\u5438\u5165\u3067\u3082\u8efd\u5ea6\u4e0d\u5b89\u306e\u6539\u5584\u304c\u3044\u304f\u3064\u304b\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31655395\/#:~:text=Effects%20of%20lavender%20on%20anxiety%3A,is%20only%20an%20indication\" target=\"_blank\" rel=\"noreferrer noopener\">pubmed.ncbi.nlm.nih.gov<\/a>\u3002\u3042\u308b\u30e1\u30bf\u89e3\u6790\u3067\u306f\u3001\u30e9\u30d9\u30f3\u30c0\u30fc\u5438\u5165\u306f\u5373\u52b9\u7684\u306b\u30b9\u30c8\u30ec\u30b9\u6307\u6a19\u3092\u4e0b\u3052\u308b\u50be\u5411\u304c\u3042\u308b\u304c\u3001\u9577\u671f\u52b9\u679c\u306f\u4e0d\u660e\u3068\u3055\u308c\u3066\u3044\u307e\u3059<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31655395\/#:~:text=analysis%20pubmed,is%20only%20an%20indication\" target=\"_blank\" rel=\"noreferrer noopener\">pubmed.ncbi.nlm.nih.gov<\/a>\u3002\u3068\u306f\u3044\u3048\u3001\u77ed\u671f\u7684\u306a\u30ea\u30e9\u30af\u30bc\u30fc\u30b7\u30e7\u30f3\u306b\u306f\u5341\u5206\u6709\u7528\u3068\u3055\u308c\u3001\u4f8b\u3048\u3070\u4e0d\u7720\u75c7\u60a3\u8005\u306b\u5c31\u5bdd\u524d\u30e9\u30d9\u30f3\u30c0\u30fc\u9999\u3092\u55c5\u3050\u7fd2\u6163\u3092\u3064\u3051\u305f\u3089\u3001\u7761\u7720\u306e\u8cea\u304c\u5411\u4e0a\u3057\u305f\u3068\u3044\u3046\u5831\u544a\u3082\u3042\u308a\u307e\u3059<a href=\"https:\/\/www.asian-nursingresearch.com\/article\/S1976-1317%2821%2900077-3\/fulltext#:~:text=Effects%20of%20Lavender%20on%20Anxiety%2C,administration%20increased%20the%20anxiolytic%20effects\" target=\"_blank\" rel=\"noreferrer noopener\">asian-nursingresearch.com<\/a>\u3002\u3053\u308c\u306f\u55c5\u899a\u523a\u6fc0\u304c\u526f\u4ea4\u611f\u795e\u7d4c\u3092\u512a\u4f4d\u306b\u3057\u3001\u5165\u7720\u3092\u4fc3\u3057\u305f\u305f\u3081\u3068\u8003\u5bdf\u3055\u308c\u3066\u3044\u307e\u3059<a href=\"https:\/\/www.asian-nursingresearch.com\/article\/S1976-1317%2821%2900077-3\/fulltext#:~:text=...%20www.asian,administration%20increased%20the%20anxiolytic%20effects\" target=\"_blank\" rel=\"noreferrer noopener\">asian-nursingresearch.com<\/a>\u3002\u307e\u305f\u30d2\u30ce\u30ad\u3084\u6749\u306a\u3069\u68ee\u6797\u7cfb\u306e\u9999\u308a\uff08\u30d5\u30a3\u30c8\u30f3\u30c1\u30c3\u30c9\uff09\u306f\u68ee\u6797\u6d74\u306e\u30ea\u30e9\u30c3\u30af\u30b9\u52b9\u679c\u306e\u8981\u3067\u3042\u308a\u3001\u3053\u308c\u3082\u5fc3\u62cd\u6570\u30fb\u8840\u5727\u4f4e\u4e0b\u52b9\u679c\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u89b3\u8449\u690d\u7269\u304c\u3042\u308b\u90e8\u5c4b\u3067\u306f\u7a7a\u6c17\u4e2d\u306e\u7cbe\u6cb9\u6210\u5206\u3067\u30b9\u30c8\u30ec\u30b9\u30db\u30eb\u30e2\u30f3\u304c\u6e1b\u3063\u305f\u3068\u3044\u3046\u7814\u7a76\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u96c6\u4e2d\u529b\u30fb\u8a8d\u77e5\u6a5f\u80fd:<\/strong> 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class=\"wp-block-heading\">\u6700\u8fd1\u306e\u7814\u7a76\u52d5\u5411<\/h3>\n\n\n\n<p><strong>\u30a2\u30ed\u30de\u30c6\u30e9\u30d4\u30fc\u306e\u30a8\u30d3\u30c7\u30f3\u30b9:<\/strong> \u88dc\u5b8c\u4ee3\u66ff\u533b\u7642\u3068\u3057\u3066\u306e\u30a2\u30ed\u30de\u30c6\u30e9\u30d4\u30fc\u306b\u79d1\u5b66\u7684\u6839\u62e0\u3092\u6c42\u3081\u308b\u7814\u7a76\u304c\u6d3b\u767a\u3067\u3059\u3002\u6700\u8fd1\u306e\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u3067\u306f\u3001\u30a2\u30ed\u30de\u30c6\u30e9\u30d4\u30fc\u306f\u4e0d\u5b89\u8efd\u6e1b\u3084\u7761\u7720\u6539\u5584\u306b\u6709\u671b\u3060\u304c\u7814\u7a76\u306e\u8cea\u306f\u307e\u3061\u307e\u3061\u3067\u3042\u308b\u3068\u7d50\u8ad6\u4ed8\u3051\u3066\u3044\u307e\u3059<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31655395\/#:~:text=analysis%20pubmed,is%20only%20an%20indication\" target=\"_blank\" rel=\"noreferrer 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href=\"https:\/\/www.jaad.org\/article\/S0190-9622(14)00090-5\/fulltext#:~:text=Twice%20daily%20application%20of%20a,with%20maximum%20of%2072.12\" target=\"_blank\" rel=\"noreferrer noopener\">jaad.org<\/a><a href=\"https:\/\/www.jaad.org\/article\/S0190-9622(14)00090-5\/fulltext#:~:text=At%20the%20end%20of%20the,with%20maximum%20of%2072.12\" target=\"_blank\" rel=\"noreferrer noopener\">jaad.org<\/a>\u3002\u6e7f\u6f64\u5264\u306e\u30bd\u30eb\u30d3\u30c8\u30fc\u30eb\u3084\u30b0\u30ea\u30bb\u30ea\u30f3\u306f\u4fdd\u6e7f\u3068\u7518\u5473\u3001\u767a\u6ce1\u5264\u306e\u30e9\u30a6\u30ea\u30eb\u786b\u9178Na\u306f\u6e05\u6383\u52a9\u52e2\u3057\u307e\u3059\u3002\u305f\u3060SLS\u306f\u53e3\u8154\u5185\u523a\u6fc0\u3084\u30a2\u30d5\u30bf\u6027\u53e3\u5185\u708e\u8a98\u767a\u306e\u6307\u6458\u3082\u3042\u308a\u3001<strong>SLS\u30d5\u30ea\u30fc\u6b6f\u78e8\u5264<\/strong>\u3082\u5897\u3048\u3066\u304d\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p><strong>\u6d17\u53e3\u5264\uff08\u30de\u30a6\u30b9\u30a6\u30a9\u30c3\u30b7\u30e5\uff09:<\/strong> 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href=\"https:\/\/karger.com\/spp\/article\/36\/4\/174\/863006\/The-Skin-Barrier-and-Moisturization-Function#:~:text=The%20Skin%20Barrier%20and%20Moisturization%3A,SCORAD%29%2C\" target=\"_blank\" rel=\"noreferrer noopener\">karger.com<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6010116\/#:~:text=It%20is%20estimated%20approximately%2015,of%20Indian%20men%20use\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002\u5b50\u3069\u3082\u3078\u306e\u30d5\u30c3\u7d20\u6b6f\u78e8\u5264\u306e\u4f7f\u7528\u306f\u6b6f\u79d1\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3067\u63a8\u5968\u3055\u308c\u3066\u304a\u308a\u3001\u4e16\u754c\u7684\u306b\u866b\u6b6f\u304c\u6fc0\u6e1b\u3057\u305f\u4e00\u56e0\u3067\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6010116\/#:~:text=whitening%20agents%20with%20Asia%20is,are%20to%20reduce%20the%20melanin\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6010116\/#:~:text=%2423%20billion%20by%202020%2C%20driven,main%20source%20of%20skin%20color\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a>\u3002\u9069\u5207\u91cf\u3067\u3042\u308c\u3070\u5b89\u5168\u6027\u3082\u9ad8\u304f\u3001WHO\u3082\u30d5\u30c3\u7d20\u6b6f\u78e8\u5264\u666e\u53ca\u3092\u63a8\u9032\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u7814\u78e8\u5264\u3068\u30b9\u30c6\u30a4\u30f3\u9664\u53bb:<\/strong> 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href=\"https:\/\/www.jaad.org\/article\/S0190-9622(14)00090-5\/fulltext#:~:text=Twice%20daily%20application%20of%20a,with%20maximum%20of%2072.12\" target=\"_blank\" rel=\"noreferrer noopener\">jaad.org<\/a><a href=\"https:\/\/www.jaad.org\/article\/S0190-9622(14)00090-5\/fulltext#:~:text=At%20the%20end%20of%20the,with%20maximum%20of%2072.12\" target=\"_blank\" rel=\"noreferrer noopener\">jaad.org<\/a>\u3002\u5373\u52b9\u3067\u3059\u304c\u4e00\u6642\u7684\u3067\u3001\u98df\u4e8b\u3084\u553e\u6db2\u3067\u6570\u6642\u9593\uff5e\u534a\u65e5\u3067\u843d\u3061\u307e\u3059\u3002\u5b89\u5168\u6027\u306f\u9ad8\u304f\u3001\u5199\u771f\u64ae\u5f71\u524d\u3084\u30a4\u30d9\u30f3\u30c8\u524d\u306b\u4fbf\u5229\u3067\u3059\u3002<\/p>\n\n\n\n<p><strong>\u53e3\u81ed\u306e\u539f\u56e0\u3068\u5bfe\u7b56:<\/strong> 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noopener\">onlinelibrary.wiley.com<\/a>\u3002\u6d17\u53e3\u5264\u306eCPC\u3084CHX\u306f\u53e3\u8154\u7d30\u83cc\u3092\u6e1b\u3089\u3057\u3001\u7279\u306b\u30e1\u30c1\u30eb\u30e1\u30eb\u30ab\u30d7\u30bf\u30f3\u7523\u751f\u83cc\u3092\u6291\u3048\u308b\u3053\u3068\u3067\u81ed\u6c17\u3092\u8efd\u6e1b\u3057\u307e\u3059\u3002ZPT\u3084\u9285\u30af\u30ed\u30ed\u30d5\u30a3\u30ea\u30f3Na\u306f\u3001VSC\u3068\u5316\u5408\u3057\u3066\u7121\u81ed\u306e\u786b\u5316\u4e9c\u925b\u3084\u30c1\u30aa\u30fc\u30eb\u932f\u4f53\u3092\u5f62\u6210\u3057\u53e3\u81ed\u3092\u5373\u5ea7\u306b\u6e1b\u3089\u3057\u307e\u3059\u3002\u30d2\u30ce\u30ad\u30c1\u30aa\u30fc\u30eb\u3084\u7dd1\u8336\u30ab\u30c6\u30ad\u30f3\u306f\u7d30\u83cc\u9175\u7d20\u3092\u963b\u5bb3\u3057VSC\u7523\u751f\u3092\u6e1b\u3089\u3059\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u81e8\u5e8a\u8a66\u9a13\u3067\u306f\u3001CHX\u6d17\u53e3\u3067\u30ac\u30b9\u30af\u30ed\u6e2c\u5b9a\u306eVSC\u6fc3\u5ea6\u304c90%\u6e1b\u5c11\u3001CPC\u3067\u308270%\u6e1b\u5c11\u306a\u3069\u5373\u52b9\u6027\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u6301\u7d9a\u671f\u9593\u306f4\uff5e8\u6642\u9593\u7a0b\u5ea6\u3067\u3001\u53e3\u81ed\u5bfe\u7b56\u306b\u306f\u5c31\u5bdd\u524d\u3084\u5916\u51fa\u524d\u306e\u4f7f\u7528\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002\u306a\u304a\u53e3\u81ed\u306e\u539f\u56e0\u304c\u820c\u82d4\u306e\u5834\u5408\u3001\u820c\u30d6\u30e9\u30b7\u3067\u6a5f\u68b0\u7684\u9664\u53bb\u3059\u308b\u3053\u3068\u3082\u52b9\u679c\u7684\u3067\u3059\u3002\u6d17\u53e3\u5264\u306b\u6eb6\u83cc\u9175\u7d20\u3084\u754c\u9762\u6d3b\u6027\u5264\uff08\u30ea\u30be\u30c1\u30fc\u30e0\u3084POE\u786c\u5316\u30d2\u30de\u30b7\u6cb9\uff09\u304c\u5165\u3063\u3066\u820c\u82d4\u3092\u8edf\u5316\u3055\u305b\u308b\u88fd\u54c1\u3082\u3042\u308a\u307e\u3059\u3002<strong>\u5fc3\u7406\u7684\u53e3\u81ed\u75c7<\/strong>\uff08\u81ea\u5206\u306f\u81ed\u3044\u3068\u601d\u3044\u8fbc\u3080\uff09\u3082\u3042\u308a\u3001\u5b9f\u969b\u7121\u81ed\u3067\u3082\u6c17\u306b\u3059\u308b\u4eba\u306b\u306f\u30ab\u30a6\u30f3\u30bb\u30ea\u30f3\u30b0\u304c\u5fc5\u8981\u3067\u3059\u3002\u30e2\u30f3\u30c0\u30df\u30f3\u306a\u3069\u3092\u4f7f\u3046\u5b89\u5fc3\u611f\u304c\u30bb\u30eb\u30d5\u30a4\u30e1\u30fc\u30b8\u6539\u5584\u306b\u7e4b\u304c\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u6b6f\u8089\u708e\u4e88\u9632:<\/strong> 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\u53e3\u8154\u5185\u7d30\u83cc\u53e2\u89e3\u6790\u304c\u9032\u307f\u3001\u866b\u6b6f\u30fb\u6b6f\u5468\u75c5\u30fb\u53e3\u81ed\u306e\u539f\u56e0\u83cc\u3060\u3051\u3067\u306a\u304f\u3001\u5065\u5eb7\u7dad\u6301\u306b\u91cd\u8981\u306a\u5171\u751f\u83cc\uff08\u553e\u6db2\u687f\u83cc\u306a\u3069\uff09\u3082\u89e3\u660e\u3055\u308c\u307e\u3057\u305f\u3002\u3053\u308c\u306b\u3088\u308a<strong>\u30d7\u30ed\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\u6b6f\u79d1<\/strong>\u306e\u7814\u7a76\u304c\u76db\u3093\u3067\u3059<a href=\"https:\/\/www.frontiersin.org\/journals\/nutrition\/articles\/10.3389\/fnut.2021.787908\/full#:~:text=Role%20of%20Probiotics%20in%20Halitosis,ability%20to%20reduce%20bacterial%20colonization\" target=\"_blank\" rel=\"noreferrer noopener\">frontiersin.org<\/a><a href=\"https:\/\/www.frontiersin.org\/journals\/nutrition\/articles\/10.3389\/fnut.2021.787908\/full#:~:text=Probiotics%2C%20especially%20Lactobacillus%20species%2C%20have,ability%20to%20reduce%20bacterial%20colonization\" target=\"_blank\" rel=\"noreferrer noopener\">frontiersin.org<\/a>\u3002Lactobacillus\u3084Streptococcus\u30b5\u30d7\u30ea\u3092\u6442\u53d6\u3055\u305b\u6b6f\u5468\u75c5\u83cc\u3092\u6e1b\u3089\u3059\u8a66\u307f\u3084\u3001\u53e3\u8154\u5185\u306b\u68f2\u307f\u7740\u304b\u305b\u308b\u30bf\u30d6\u30ec\u30c3\u30c8\u578b\u30d7\u30ed\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\u3082\u5e02\u8ca9\u3055\u308c\u59cb\u3081\u307e\u3057\u305f\u3002Frontiers\u8a8c\u306e2021\u30ec\u30d3\u30e5\u30fc\u3067\u306f\u3001L. salivarius\u7b49\u306e\u7279\u5b9a\u83cc\u682a\u306f\u820c\u82d4VSC\u7523\u751f\u83cc\u3092\u6291\u3048\u53e3\u81ed\u6e1b\u5c11\u306b\u6709\u7528\u3068\u7d50\u8ad6\u3057\u3066\u3044\u307e\u3059<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10506127\/#:~:text=health,Prevention%20of%20halitosis\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/www.frontiersin.org\/journals\/nutrition\/articles\/10.3389\/fnut.2021.787908\/full#:~:text=Role%20of%20Probiotics%20in%20Halitosis,ability%20to%20reduce%20bacterial%20colonization\" target=\"_blank\" rel=\"noreferrer noopener\">frontiersin.org<\/a>\u3002\u3053\u3046\u3057\u305f\u83cc\u30c8\u30ea\u30fc\u30c8\u30e1\u30f3\u30c8\u306f\u307e\u3060\u88dc\u52a9\u7684\u3067\u3059\u304c\u3001\u5c06\u6765\u306f\u300c\u30d6\u30af\u30d6\u30af\u3046\u304c\u3044\u3067\u5584\u7389\u83cc\u3092\u690d\u3048\u308b\u6d17\u53e3\u6db2\u300d\u306a\u3069\u304c\u73fe\u308c\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u5b9f\u969b\u3001\u53e3\u8154\u30d7\u30ed\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\u542b\u6709\u306e\u6b6f\u78e8\u5264\u30fb\u6d17\u53e3\u6db2\u3082\u7814\u7a76\u6bb5\u968e\u306b\u3042\u308a\u307e\u3059\u3002\u307e\u305f\u6b6f\u57a2\u3092\u30d0\u30a4\u30aa\u30d5\u30a3\u30eb\u30e0\u3054\u3068\u7834\u58ca\u3059\u308b<strong>\u9175\u7d20\u30ab\u30af\u30c6\u30eb<\/strong>\u3084\u3001CRISPR\u3067\u53e3\u8154\u6709\u5bb3\u83cc\u3060\u3051\u3092\u6bba\u3059\u6280\u8853\u3082\u6a21\u7d22\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3086\u304f\u3086\u304f\u306f\u6b6f\u78e8\u5264\u306b\u30d7\u30e9\u30b9\u30df\u30c9DNA\u304c\u5165\u3063\u3066\u3044\u3066\u3001\u53e3\u8154\u5185\u3067\u60aa\u7389\u83cc\u907a\u4f1d\u5b50\u3092\u7de8\u96c6\u3059\u308b\u306a\u3093\u3066SF\u3082\u5b9f\u73fe\u3059\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p><strong>AI\u3068\u30b9\u30de\u30fc\u30c8\u30c7\u30d0\u30a4\u30b9:<\/strong> 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href=\"https:\/\/www.kao.com\/jp\/binkanhada\/ingredient_01_01\/#:~:text=%E3%80%8C%E8%82%8C%E8%8D%92%E3%82%8C%E3%83%BB%E8%8D%92%E3%82%8C%E6%80%A7%E3%80%8D%E3%80%8C%E3%81%AB%E3%81%8D%E3%81%B3%E3%82%92%E9%98%B2%E3%81%90%E3%80%8D%E3%80%8C%E6%97%A5%E7%84%BC%E3%81%91%E3%81%AB%E3%82%88%E3%82%8B%E3%82%B7%E3%83%9F%E3%83%BB%E3%82%BD%E3%83%90%E3%82%AB%E3%82%B9%E3%82%92%E9%98%B2%E3%81%90%E3%80%8D%E3%80%8C%E7%9A%AE%E8%86%9A%E3%81%AE%E6%AE%BA%E8%8F%8C%E3%80%8D%E3%81%AA%E3%81%A9%E3%80%81%E5%8A%B9%E6%9E%9C%E3%81%AE%E3%81%82%E3%82%8B%E6%9C%89%E5%8A%B9%E6%88%90%E5%88%86%E3%81%8C%E9%85%8D%E5%90%88%E3%81%95%E3%82%8C%E3%81%A6%E3%81%84%E3%82%8B%E3%81%AE%E3%81%A7%E3%81%9D%E3%81%AE%E5%8A%B9%E6%9E%9C%E3%82%92%E8%A8%B4%E6%B1%82%E3%81%A7%E3%81%8D%E3%81%BE%E3%81%99%E3%80%82%E3%81%BE%E3%81%9F%E3%80%8C%E8%96%AC%20%E7%94%A8%E3%80%8D%E3%81%A8%E3%81%AF%E3%80%8C%E5%8C%BB%E8%96%AC%E9%83%A8%E5%A4%96%E5%93%81%E3%80%8D%E3%81%A7%E8%AA%8D%E3%82%81%E3%82%89%E3%82%8C%E3%81%A6%E3%81%84%E3%82%8B%E8%A1%A8%E7%A4%BA%E3%81%A7%E3%81%99%E3%81%AE%E3%81%A7%E3%80%8C%E8%96%AC%E7%94%A8%EF%BC%9D%E5%8C%BB%E8%96%AC%E9%83%A8%E5%A4%96%E5%93%81%E3%80%8D%E3%81%A8%E3%81%AA%E3%82%8A%E3%81%BE%E3%81%99%E3%80%82\" 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href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=Active%20ingredients%20for%20acne%20in,BPO%2C%20benzoyl%20peroxide%3B%20EGCG%2C%20epigallocatechin%E2%80%903%E2%80%90gallate\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12023719\/#:~:text=Alpha%E2%80%90hydroxy%20acid%2C%20linoleic%20acid%2C%20salix,BPO%2C%20benzoyl%20peroxide%3B%20EGCG%2C%20epigallocatechin%E2%80%903%E2%80%90gallate\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a> <a href=\"https:\/\/www.mdpi.com\/1420-3049\/27\/6\/2010#:~:text=which%20leads%20to%20the%20lowering,that%20the%20science%20behind%20cleansers\" target=\"_blank\" rel=\"noreferrer noopener\">mdpi.com<\/a><a href=\"https:\/\/www.mdpi.com\/1420-3049\/27\/6\/2010#:~:text=types%3A%20soap,s%29%20in%20skin%20cleansers%E2%80%94and\" target=\"_blank\" rel=\"noreferrer noopener\">mdpi.com<\/a> <a 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href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9669136\/#:~:text=Results%3A%20%20Hair%20density%20and,to%20be%20decreased%20by%20KCZ\" target=\"_blank\" rel=\"noreferrer noopener\">pubmed.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9669136\/#:~:text=appeared%20to%20be%20decreased%20by,KCZ\" target=\"_blank\" rel=\"noreferrer noopener\">pubmed.ncbi.nlm.nih.gov<\/a> <a href=\"https:\/\/www.mdpi.com\/2079-9284\/12\/4\/155#:~:text=MDPI%20www.mdpi.com%20%20,6%E2%80%9312%20weeks%2C%20particularly%20when\" target=\"_blank\" rel=\"noreferrer noopener\">mdpi.com<\/a><a href=\"https:\/\/www.mdpi.com\/2079-9284\/12\/4\/155#:~:text=Hexsel%20et%20al.%20,with%20genistein%20or%20Centella%20asiatica\" target=\"_blank\" rel=\"noreferrer noopener\">mdpi.com<\/a> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38877766\/#:~:text=Results%3A%20%20The%20quality%20of,as%20adjuncts%20to%20medical%20treatment\" target=\"_blank\" rel=\"noreferrer noopener\">pubmed.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38877766\/#:~:text=dermocosmetics%20in%20acne%20to%20improve,as%20adjuncts%20to%20medical%20treatment\" target=\"_blank\" rel=\"noreferrer noopener\">pubmed.ncbi.nlm.nih.gov<\/a> <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11268769\/#:~:text=applications%20of%20AHAs%2C%20particularly%20in,Regulatory%20compliance%20is\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11268769\/#:~:text=analysis%20reveals%20a%20nuanced%20understanding,dermatology%2C%20emphasizing%20the%20necessity%20for\" target=\"_blank\" rel=\"noreferrer noopener\">pmc.ncbi.nlm.nih.gov<\/a> <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0965229922000346#:~:text=The%20effect%20of%20lavender%20on,In%20recent%20years%2C%20many\" target=\"_blank\" rel=\"noreferrer noopener\">sciencedirect.com<\/a> <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/odi.14172#:~:text=Aetiology%20and%20associations%20of%20halitosis%3A,poor%20oral%20hygiene%20practices\" target=\"_blank\" rel=\"noreferrer noopener\">onlinelibrary.wiley.com<\/a><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/odi.14172#:~:text=Eighty%20to%20ninety%20percent%20of,poor%20oral%20hygiene%20practices\" target=\"_blank\" rel=\"noreferrer noopener\">onlinelibrary.wiley.com<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"\u7f8e\u5bb9\u76ae\u819a\u79d1\u533b\u306e\u305f\u3081\u306e\u9999\u7ca7\u54c1\u30ab\u30c6\u30b4\u30ea\u5225\u30ac\u30a4\u30c9 1. \u30b9\u30ad\u30f3\u30b1\u30a2\u5316\u7ca7\u54c1\uff08\u4fdd\u6e7f\u30fb\u6d17\u6d44\u30fb\u89d2\u8cea\u30b1\u30a2\u30fb\u7f8e\u767d\u306a\u3069\uff09 \u4e3b\u8981\u6210\u5206\u3068\u4f5c\u7528\u6a5f\u5e8f \u4fdd\u6e7f\u5264: 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